PubMed Health⌕ Search

Biomedical subjects

Adrian Bruce

Publications and source records attributed to Adrian Bruce.

2 recordsLinked to original sources

Circinate corneal scarring.

A 56-year-old man presented with symptoms of monocular diplopia and reduced vision in his left eye. Visual acuities were R6/6, L6/12. At his previous visit left visual acuity was 6/6. An irregular area of anterior corneal stromal scarring was evident, encroaching on the visual axis of the left eye. Rigid lens fitting improved left visual acuity to 6/6, however, lens wear caused a corneal abrasion over the lesion after one to two hours of wear. Several other contact lens and surgical strategies were employed to successfully address the visual requirements of the patient.

Cicatrix↗

Local oxygen transmissibility of disposable contact lenses.

AIM: Despite global standardisation in measurement of oxygen transmissibility (Dk/t), in our clinic we continue to see limbal vasculature changes in patients wearing some disposable lenses. The use of central Dk/t as a simple designator of a contact lens oxygen performance has clearly failed, it being acknowledged as often unrelated to the oxygen performance of the lens periphery. This study investigates a new criterion for contact lens oxygen transmissibility, the local Dk/t. METHOD: The study measured 20 spherical disposable lens brands (power range: -15.00 to +8.00 D) and 8 toric lens brands (power range: -8.00 to +4.00 D sphere, with a -1.00 D/-1.25 D x 180). An electro-mechanical gauge (Heidenhain, Germany) was used to measure lens thickness (t) at different positions on the lens. Oxygen permeability (Dk) of each lens material was calculated from the equation Dk =1.67 e (0.0397 x water content) of Morgan and Efron [Contact Lens Anterior Eye 21 (1998) 3] who used ISO/ANSI standard methodologies. The local Dk/t value was calculated from the point of maximum thickness on the lens and compared to the criterion of 12 Fatt units set by Benjamin [Int. Contact Lens Clin. 23 (1996) 188], to provide corneal oxygenation greater than or comparable to that available in the normal closed eye. RESULTS: All lens types with a water content over 65% had a local Dk/t of 12 Fatt units or more for most or all lens powers: CIBAVision FocusDailies, Bausch & Lomb Soflens66, CooperVision Actifresh400, and CIBAVision PrecisionUV. In addition, some lenses in the 55-62% water content range had some lens powers with a local Dk/t in excess of 12: CooperVision Proclear, Johnson & Johnson Acuvue 1 and CIBAVision Focus 2 week. None of the disposable toric lenses had a minimum Dk/t of 12 or more. The silicone-hydrogels, Bausch & Lomb PureVision and CIBAVision Focus Night&Day, comfortably exceeded Dk/t of 50 for all lens powers. CONCLUSION: Some current disposable soft lenses have local Dk/t values below physiological requirements. Contact lens manufacturers and international standards organisations should consider introducing the labelling of local Dk/t values on lens packaging so that clinicians can make informed prescribing decisions.

Journal Article↗