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Biomedical subjects

Adrienne Keller

Publications and source records attributed to Adrienne Keller.

7 recordsLinked to original sources

Burden of phase-specific sexual dysfunction with SSRIs.

OBJECTIVE: This study examines phase-specific sexual dysfunction among patients who are being treated for major depression and who do not meet criteria for global sexual dysfunction. METHODS: 6297 adult outpatients receiving antidepressant monotherapy completed the Changes in Sexual Functioning Questionnaire (CSFQ). The sub-sample for this study (n = 3114) comprises participants who were receiving treatment with a SSRI or SNRI and did not meet the gender-specific criterion for global sexual dysfunction on the CSFQ. RESULTS: Among this sub-sample, 95.6% of women and 97.9% of men exhibited impairment in at least one phase of sexual functioning. Men were significantly more likely than women to experience dysfunction in the desire phase (91.2% vs. 79.0%; OR = 2.76; 95% C.I. = 2.14 to 3.5) and the orgasmic phase (85.1% vs. 45.4%; OR = 6.9; 95% C.I. = 5.6 to 8.4) but were significantly less likely than women to experience dysfunction in the arousal phase (71.9% vs. 83.3%; OR = .51; 95% C.I. = .43 to .62). The prevalence of phase-specific dysfunction did not vary significantly by SSRI/SNRI for males or females. CONCLUSION: Among patients who do not experience clinically significant global sexual dysfunction on SSRI/SNRI monotherapy, dysfunction in at least one phase of the sexual response cycle is very common and may reduce sexual health-related quality of life.

Adrenergic Uptake Inhibitors↗

Decreased physical activity among Head Start children with a history of wheezing: use of an accelerometer to measure activity.

Asthma is a severe problem among inner city children, and recent evidence suggests that both allergen exposure and lifestyle can impact the disease early in childhood. This study was designed to investigate the association between physical activity and wheezing among a population of inner city children enrolling in Head Start. The parents of children aged 3-5 years responded to a questionnaire (N = 144) to determine the presence and severity of wheezing and asthma. Information was also gathered regarding home environment, food frequency, and presence of other allergic diseases. Serum was obtained to measure total IgE and specific IgE levels to common allergens. Height and weight for body mass index were recorded. Lastly, motion sensor wristwatches (Actiwatch) were worn continuously by a subset of these children (n = 54) for 6 or 7 days. Physical activity measured with the motion sensor was decreased among children with a history of wheezing. The significant differences involved those measures of activity relating to prolonged or sustained physical activity. The correlates of asthma associated with decreased levels of physical activity included: 1) a history of wheezing in the last 12 months, 2) the diagnosis of asthma, and 3) presentation to the emergency room in the last 12 months for wheezing or asthma. In a preschool-age population, decreased physical activity was observed among children with a history of asthma or wheezing. Decreased physical activity could contribute to persistence of asthma or put children at higher risk for obesity and other chronic diseases.

Antibodies, Anti-Idiotypic↗

Juvenile sex offender re-arrest rates for sexual, violent nonsexual and property crimes: a 10-year follow-up.

We report the results of a 10-year follow-up recidivism study of two sex offender treatment programs for incarcerated juvenile sex offenders (JSOs) in Virginia. The programs vary in environment and intensity. The more intense JSO program ("self-contained") operates in specialized living units that are separate from those of the general juvenile incarcerated population. In the less intense program ("prescriptive"), JSOs remain housed with the general population of juvenile offenders. Arrest and incarceration data through January 2003 were obtained for 261 male JSOs released between 1992 and 2001. The inclusion of adult incarceration data allowed for a more accurate assessment of the actual time at risk for sexual re-offending. Outcomes are re-arrest rates, length of time to re-arrest and type of offense (property, nonsexual assault, sexual) on re-arrest, with analyses using survival curve functions. For both groups, actual re-arrest is most likely to be for a nonsexual person offense (31 and 47%, respectively) and least likely to be for a sexual offense (<5% for both groups). Comparing the nonequivalent groups, the self-contained treatment group has a lower predicted re-arrest rate and a longer mean time to re-arrest, for all types of offenses, than the prescriptive treatment group. In addition, juveniles who indicate high levels of impulsive/antisocial behaviors are significantly more likely to recidivate compared to juveniles with low-levels of impulsive/antisocial behaviors, regardless of treatment type. This is the first 10-year follow-up study of treatment outcomes for a relatively large sample of males who were incarcerated for sexual offenses as juveniles.

Adolescent↗

Feasibility and benefits of a parent-focused preschool child obesity intervention.

OBJECTIVES: This field study tested the feasibility and benefits of a program to promote 6 targeted parental behaviors to prevent obesity in children served by the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). METHODS: Two WIC sites participated in a nonrandomized, controlled 1-year prospective study to assess parents' self-reported behavior changes. RESULTS: Statistical analyses of preintervention and postintervention assessments of parental behavior demonstrated significant changes in 2 behaviors: frequency of offering the child water and frequency of engaging in active play with the child. In both cases, the intervention proved effective in increasing the desired behavior. CONCLUSIONS: The findings demonstrate the feasibility of changing parental behaviors through multidimensional education in a WIC clinic setting.

Adult↗

Fit WIC: attitudes, perceptions and practices of WIC staff toward addressing childhood overweight.

OBJECTIVE: To assess the attitudes, perceptions, and practices of staff of the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) in providing nutrition education on childhood overweight topics with WIC participants. DESIGN: Descriptive and correlational study. SETTING: WIC clinics in Virginia. PARTICIPANTS: 106 employees working in direct contact with WIC participants. MEAN OUTCOME MEASURE(S): Demographic information; comfort level and frequency of discussing childhood overweight-related topics with participants; perception of WIC's ability to prevent and help address overweight among children and adults; body mass index (BMI); and attitudes toward personal weight. ANALYSIS: Descriptive statistics, regression, and analysis of variance. RESULTS: WIC staff in this study reported a lack of comfort, practice, and confidence in addressing and/or preventing childhood overweight with WIC participants, with differences existing based on job title (P < .05). Barriers to implementing programs included perceived attitudes of participants, transportation, time, cultural issues, and childcare. Staff BMIs were significantly correlated to ethnicity, age, feeling overweight, unhappiness with current weight, and comfort level discussing fruit and vegetable intake and physical activity (P < .05). CONCLUSIONS AND IMPLICATIONS: Staff training, health promotion programs, and culturally relevant educational materials are warranted for WIC staff to build a strong knowledge base and promote self-efficacy about childhood overweight-related topics.

Adult↗

Reliability and construct validity of the Changes in Sexual Functioning Questionnaire short-form (CSFQ-14).

The Changes in Sexual Functioning Questionnaire (CSFQ) is a 36-item clinical and research instrument identifying five scales of sexual functioning. This study documents the internal consistency and factor structure of a 14-item version of the CSFQ (CSFQ-14), which yields scores for three scales corresponding to the phases of the sexual response cycle (i.e., desire, arousal, and orgasm) as well as the five scales of the original CSFQ. Factor analysis confirms the construct validity of the CSFQ-14 as a global measure of sexual dysfunction. The CSFQ-14 and the individual scales exhibit strong internal reliability.

Adult↗