Biomedical subjects

Agata Kot-Wasik

Publications and source records attributed to Agata Kot-Wasik.

4 recordsLinked to original sources

PubMed2005

Determination of nonsteroidal antiinflammatory drugs in water samples using liquid chromatography coupled with diode-array detector and mass spectrometry.

An analytical method for the determination of trace levels of six different nonsteroidal antiinflammatory drugs (NSAIDs) in water samples has been developed and validated. Environmentally relevant pharmaceuticals were chosen according to human consumption in Poland. Final analysis of the target compounds was performed by RP LC-diode-array detection-MS, whereas sample preparation included an SPE step. For this SPE step, a number of packing materials, such as LiChrolut RP-18, calixarene, Strata-X, BAKERBOND Narc-2, BAKERBOND Polar Plus, BAKERBOND styrene divinylbenzene-1, and Discovery DSC-18, were used, and their respective advantages and disadvantages in this study were discussed. The RP-18 phase was found to be the most retentive for all analytes. The detection limits for compounds in surface waters were varied from 0.005 for diflunisal to 0.095 microg/L for ibuprofen. The average recoveries of NSAIDs from the surface water samples ranged from 80 up to 103%. RSD value is relatively low (from 4% for fenoprofen up to 8% for ibuprofen). The performance of the method was tested with several environmental water samples.

Anti-Inflammatory Agents, Non-Steroidal↗

PubMed2004

Passive sampling and/or extraction techniques in environmental analysis: a review.

The current state-of-the-art of passive sampling and/or extraction methods for long-term monitoring of pollutants in different environmental compartments is discussed in this review. Passive dosimeters that have been successfully used to monitor organic and inorganic contaminants in air, water, sediments, and soil are presented. The application of new approaches to the determination of pollutants at the sampling stage is discussed. The main milestones in the development of passive techniques for sampling and/or extraction of analytes, and in biomonitors used in environmental analysis, are summarized in this review. Passive samplers and biomonitors are compared.

Journal Article↗

PubMed2004

Monitoring of organic pollutants in coastal waters of the Gulf of Gdańsk, Southern Baltic.

This paper presents an overview of changes in organic pollution of coastal waters of the Gulf of Gdańsk (Baltic Sea). Toxic pollutants including volatile organic compounds (VOC), volatile organohalogen compounds (VOX), chlorophenols, phenoxyacids, polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs) were determined in seawater from the Gulf of Gdańsk coastal waters in the period 1996-2001. In the case of the Gulf of Gdańsk, non-conservative behaviour of VOC was observed due to random temporal and spatial of inputs along the Vistula estuary and to the dilution of VOC-enriched river water with seawater. The concentrations of VOX in seawater decreased throughout the period and the concentrations of VOX were in the range of few ng dm(-3) up to 250 ng dm(-3), similar to estuaries elsewhere. The average concentrations of chlorophenols and phenoxyacids were between 0.1 and 6.0 and 0.05 and 2.2 microg dm(-3), respectively. However, remarkably high concentrations of 2,4-dichlorophenol (6 microg dm(-3)) were obtained in samples collected from the Vistula River. Generally concentrations of PCBs did not exceed few ng dm(-3) with the exception of 1999, when all samples exhibited elevated concentrations of PCBs. In addition, higher concentrations of PCBs in the open sea compared to river waters suggested localised inputs. Due to the ability of most organic pollutants to bioaccumulate and biomagnify, especially the persistent organic pollutants, continued monitoring is of crucial importance for the health of marine life in the Gulf of Gdańsk.

Animals↗

PubMed2003

Physical, chemical, and biological changes in the Gulf of Gdańsk ecosystem (southern Baltic sea).

This review presents the present state of knowledge of the physical, chemical, and biological changes in waters of the Gulf of Gdańsk (Baltic Sea). The general characteristics of the Baltic Sea and the Gulf of Gdańsk with brief description of changes in the ecosystem are included. Among meteorological parameters describing climate in the coastal zone, water temperature changes together with considerations of precipitation and sea level are presented. It has been confirmed that the sea level rise over the past 40 yr was very distinct. Throughout the past 30 yr an evident increase in eutrophication has been observed. Therefore, changes in salinity, oxygen content, and nutrient fluctuations with special attention paid to variability in silicate, nitrate, and phosphate concentrations in the water layer are presented. Also, discussion on the presence of toxic pollutants, such as heavy metals, PCBs, PAHs, and some pesticides, in the water body of the Gulf of Gdańsk has been included. Because of their ability to bioaccumulate and biomagnify in living organisms, these substances are of crucial importance for future marine life in the Gulf of Gdańsk. Finally, biological conditions of the coastal waters of the Gulf of Gdańsk were discussed. Data show that the ecosystem structure of the Gulf of Gdańsk has undergone tremendous changes. The species pattern has changed significantly--many species have disappeared and others have become dominant.

Animals↗