Biomedical subjects

Agnieszka Wasik-Kuprianowicz

Publications and source records attributed to Agnieszka Wasik-Kuprianowicz.

3 recordsLinked to original sources

PubMed2005

Is breast reduction in puberty indicated? Retrospective observations of patients with a local hypersensitivity of estrogen and progesterone receptors.

The authors described two women in whom at the age of 14 and 15 diagnosed was gigantomasty and a hypersensitivity of the estrogen receptor. In both the patients at that time a significant increase of the estrogen and progesterone receptors in the breast glandular tissue was ascertained. The immunohistochemical investigation shows a significant higher sensitivity of the progesterone and estrogen receptors. In both the girls observed was gigantomasty with hyperlordosis, deformities of the chest and back, skin changes, orthopnoe. In both the patients a total mastectomy was performed. Both the girls had after surgery a normal menstruation, were married with normal sexual activity. One of the patients had a normal delivery two years ago.

Adolescent↗

PubMed2004

[Darier disease type 1].

Darier disease (follicular dyskeratosis) is a rare genodermatosis determined by an autosomal dominant gene with variable penetration, characterized by a symmetrical eruption of hyperkeratotic papules with predilection to the seborrheic areas of the body. Unilateral, focal form is the one of the rare type of the Darier disease. Two clinical and genetical phenotypes of the segmental Darier disease have been recently reported: type 1--in which the skin outside of the localized manifestation is normal and type 2--showing a segmental affection in combination with diffuse skin involvement. The patient with type 1 segmental Darier disease is presented because of rare occurrence, diagnostic and therapeutic difficulties as well. The first keratotic papules on the left side of his trunk appeared at the age 14. The correct diagnosis based on clinical and histological picture has been established 38 years latter.

Darier Disease↗

PubMed2002

[Skin changes during the course of selected endocrinologic diseases in children and adolescents].

The authors presented skin lesions which may be observed in selected endocrinopathies in children and adolescents. Functional disturbances of endocrine glands in which skin lesions may develop are dysfunction of the adrenals, gonads in case of children, thyroid diseases and diabetes type 1. The authors presented also a detailed description of skin symptoms observed in hyperthyrosis and hypothyrosis. They emphasised that the most common form of hyperthyrosis in children and adolescents is Graves disease. Also broadly dermatological lesions which may develop in diabetes type 1 they described.

Adolescent↗