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Ahmet Tekin

Publications and source records attributed to Ahmet Tekin.

6 recordsLinked to original sources
PubMed2005

Determination of operation time in colorectal diseases: preoperative chemotherapy application.

BACKGROUND: Our aim was to determine the time it takes for wound healing to return to normal in cases where patients have undergone preoperative chemotherapy. MATERIALS AND METHODS: Eighty-four Wistar-albino rats were included in the study. Twelve of them were placed in the control group (Group I), with no further drug administration. Another 12 rats were placed in a sham group (Group II) and were peritoneally injected with 1 cc of isotonic saline solution 5 days a month, for a period of 6 months. The remaining 60 rats were placed in five chemotherapy groups (Groups III-VII) and were administered 20 mg/kg 5-fluorouracil through peritoneal injection, 5 days a month for a period of 6 months. At the end of the sixth cure, 12 rats from the control (Group I), sham (Group II), and chemotherapy groups (Group III) were operated on, and an intestinal transsection was applied to the rectosigmoid junction, followed by one-by-one anastomosis using 5/0 vicryl. Other groups (Groups IV-VI) with chemotherapy treatment were operated on at 1-week intervals and subjected to the same procedure. The subjects were reoperated on on the eleventh day. A full-layer 4 x 4 cm piece was removed from the abdominal wall containing the previous incision line at the middle, for tensile strength pressure measurements. In addition, a 4 cm colon segment was removed for bursting pressure measurements. Plasma albumin and tissue hydroxyproline levels were measured, and fibroblast numbers were counted in the sections prepared from the abdominal wall. RESULTS: The control and sham groups were found to be similar to each other with respect to all parameters measured (P > 0.05). Significant reductions were observed in all parameters in the early chemotherapy groups compared with the control and sham groups (P <0.05). All parameters measured in Groups V, VI, and VII were found to be similar to those in the control and sham groups (P <0.05). CONCLUSION: Wound healing is impaired in rats with chemotherapy, but following the second week after the chemotherapy, disrupted parameters return to their normal levels.

Abdominal Wall↗
PubMed2003

[Diaphragmatic rupture in abdominal trauma].

BACKGROUND: The aim of the study is to evaluate the patients with diaphragmatic rupture due to penetrating or blunt abdominal trauma. METHODS: Thirty-eight patients with diaphragmatic rupture due to penetrating or blunt abdominal trauma were investigated retrospectively. RESULTS: The average age was 41,72 and there were 31 male and seven female patients. The injury forms were penetrating trauma in 22 (58%) and blunt trauma in 16 (42%) cases. Associated abdominal organ injuries were found in 27 (71%) cases. Among 47 diaphragmatic ruptures, 27 (57%) were on the left and 20 (43%) were on the right side. The average diameter of the rupture was 5,45 (1-20) cm. Management of the diaphragmatic rupture and other associated organ injuries were accomplished through laparotomy. Morbidity was developed in 18 cases and mortality in four cases with associated abdominal organ injuries. CONCLUSION: Diaphragmatic rupture results in high morbidity and mortality due to associated organ injuries.

Adolescent↗
PubMed2003

Nodular regenerative hyperplasia of the liver: a case report.

Nodular regenerative hyperplasia of the liver is characterized by hepatocellular nodules distributed throughout the liver in the absence of fibrous septa between the nodules. In the literature, most reports have been single cases so that the prevalence and clinical significance of the disease is not exactly known. The critical lesion is obliterative portal venopathy which is obstruction to terminal radicals of hepatic arterioles and portal venules, possibly secondary to endothelial cell damage. Resultant hepatic ischemia may be responsible for induction of the nodular regenerative change. Portal hypertension which is secondary to nodular regenerative hyperplasia and is often complicated by bleeding esophageal varices. We report a rare case of nodular regarative hyperplasia of the liver, with onset of symptom in childhood.

Adolescent↗
PubMed2002

Video-assisted extracorporeal appendectomy.

BACKGROUND: Despite many randomized controlled trials, there are still several important doubts about laparoscopic appendectomy. Longer operative time and greater cost are the two major disadvantages of the laparoscopic technique. PATIENTS AND METHODS: In current techniques of laparoscopic appendectomy, the appendix is ligated and divided within the abdominal cavity. We have performed 423 laparoscopic appendectomies using an extracorporeal technique during the last 8 years. In this technique, the appendix is delivered to the surface through the cannula, and appendectomy is carried out extracorporally. RESULTS AND CONCLUSION: The extracorporeal technique of appendix removal can be performed as safely and efficiently as the open technique. We report our data on the series of 423 operations, in which we had the encouraging experience that the video-assisted extracorporeal technique is a practical and reasonable alternative to the traditional laparoscopic technique.

Adolescent↗
PubMed2002

Biliary stones and stenoses: diagnostic value of magnetic resonance cholangiography.

BACKGROUND/AIMS: To evaluate the accuracy of magnetic resonance cholangiography for detection of bile duct calculi and stenosis. METHODS: Half-Fourier single-shot rapid acquisition with relaxation enhancement sequence magnetic resonance cholangiography was performed prospectively in 68 patients who were suspected of having choledocholithiasis or biliary tree stenosis. On the basis of findings at ultrasound, computed tomography, endoscopic retrograde or percutaneous cholangiography, intraoperative cholangiography or choledocoscopy and exploration, final diagnoses were normal bile ducts (n=8), choledocholithiasis (n=28), benign or malignant stenosis (n=32). RESULTS: Choledocholithiasis was diagnosed with a sensitivity of 96% and a specificity of 98%. False negative readings occurred due to stones less than two mm at in size at the distal common bile duct. A false diagnosis of choledocholithiasis (single impacted stone) by magnetic resonance cholangiography occurred in only one case for whom the final diagnosis was main bile duct adenocarcinoma, suspected on endoscopic retrograde cholangiography and confirmed at surgery. Bile duct stenosis was diagnosed with a sensitivity of 97% and a specificity of 94%. CONCLUSIONS: With magnetic resonance cholangiography, bile duct calculi and stenosis can be diagnosed with high accuracy. It is a fast, accurate and noninvasive alternative to endoscopic retrograde cholangiography in the evaluation of biliary tract disease.

Journal Article↗