[RIKEN structural genomics/proteomics initiative (RSGI)].
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Biomedical subjects
Publications and source records attributed to Akiko Tanaka.
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PURPOSE: Esotropia with high myopia is due to elongation of the eyeball, which becomes too large to fit within the muscle cone. To demonstrate the elongation, we measured the size of the eyeballs. SUBJECTS AND METHODS: Five patients with esotropia with high myopia(myopic esotropia group), 8 patients with high myopia without esotropia(high myopia group), and 10 controls(control group) were examined. Using magnetic resonance imaging, we measured the outer axial length and the maximum transverse size of the eyeballs. RESULTS: The outer axial length(mean +/- standard deviation) was greater in the order of the myopic esotropia group(31.6 +/- 1.59 mm), the high myopia group(27.9 +/- 2.22 mm), and the control group(23.7 +/- 1.59 mm) (p < 0.01). The maximum transverse size was also greater in the order of the myopic esotropia group(25.0 +/- 0.99 mm), the high myopia group (24.9 +/- 1.27 mm), and the control group(23.1 +/- 1.38 mm). The outer axial length of the eyeballs in the myopic esotropia group was significantly longer than in the high myopia group and the control group, and the maximum transverse size was significantly longer than in the control group. CONCLUSIONS: The elongation of the eyeballs of the myopic esotropia group was demonstrated. A high incidence of esotropia may occur when the outer axial length of high myopia is longer than 30 mm.
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In a middle-class sample of mothers of 2-year-olds, adult attachment classifications measured in the Adult Attachment Interview (AAI) were related to maternal self-reported emotional well-being and observed parenting behavior, and the potential mediating and moderating roles of maternal emotion were tested. Mothers classified as dismissing on the AAI reported significantly lower levels of positive affectivity. Mothers classified as preoccupied reported significantly higher levels of negative affectivity and anxiety. Preoccupied mothers were observed to be significantly higher on angry/intrusive parenting, but this association was not mediated by attachment-related differences in maternal emotion. Maternal emotional well-being did, however, moderate the associations between adult attachment and parenting behavior: Dismissing attachment was significantly associated with lower warmth/responsiveness only among mothers with higher levels of depressive symptoms.