Biomedical subjects

Albert V van den Berg

Publications and source records attributed to Albert V van den Berg.

5 recordsLinked to original sources

PubMed2006

The time course of binocular rivalry reveals a fundamental role of noise.

When our two eyes view incongruent images, we experience binocular rivalry: An ongoing cycle of dominance periods of either image and transition periods when both are visible. Two key forces underlying this process are adaptation of and inhibition between the images' neural representations. Models based on these factors meet the constraints posed by data on dominance periods, but these are not very stringent. We extensively studied contrast dependence of dominance and transition durations and that of the occurrence of return transitions: Occasions when an eye loses and regains dominance without intervening dominance of the other eye. We found that dominance durations and the incidence of return transitions depend similarly on contrast; transition durations show a different dependence. Regarding dominance durations, we show that the widely accepted rule known as Levelt's second proposition is only valid in a limited contrast range; outside this range, the opposite of the proposition is true. Our data refute current models, based solely on adaptation and inhibition, as these cannot explain the long and reversible transitions that we find. These features indicate that noise is a crucial force in rivalry, frequently dominating the deterministic forces.

Adaptation, Physiological↗

PubMed2006

Representation of head-centric flow in the human motion complex.

Recent neuroimaging studies have identified putative homologs of macaque middle temporal area (area MT) and medial superior temporal area (area MST) in humans. Little is known about the integration of visual and nonvisual signals in human motion areas compared with monkeys. Through extra-retinal signals, the brain can factor out the components of visual flow on the retina that are induced by eye-in-head and head-in-space rotations and achieve a representation of flow relative to the head (head-centric flow) or body (body-centric flow). Here, we used functional magnetic resonance imaging to test whether extra-retinal eye-movement signals modulate responses to visual flow in the human MT+ complex. We distinguished between MT and MST and tested whether subdivisions of these areas may transform the retinal flow into head-centric flow. We report that interactions between eye-movement signals and visual flow are not evenly distributed across MT+. Pursuit hardly influenced the response of MT to flow, whereas the responses in MST to the same retinal stimuli were stronger during pursuit than during fixation. We also identified two subregions in which the flow-related responses were boosted significantly by pursuit, one overlapping part of MST. In addition, we found evidence of a metric relation between rotational flow relative to the head and fMRI signals in a subregion of MST. The latter findings provide an important advance over published single-cell recordings in monkey MST. A visual representation of the rotation of the head in the world derived from head-centric flow may supplement semicircular canals signals and is appropriate for cross-calibrating vestibular and visual signals.

Adult↗

PubMed2005

An illusory transformation of optic flow fields without local motion interactions.

The focus of expansion (FOE) of a radially expanding optic flow pattern that is overlapped by unidirectional laminar flow is perceptually displaced in the direction of that laminar flow. There is continuing debate on whether this effect is due to local or global motion interactions. Here, we show psychophysically that under conditions without local motion transparency the illusion becomes weaker but can still be observed. In our experiments, the radial and laminar-flow fields were not presented with overlap but separately to the left and right halves of the visual field with a blank vertical strip of 15 degrees horizontal width in between. The illusory shift observed in this condition cannot be explained by local motion interactions because (a) no transparent motion was present in the stimulus, and (b) the receptive fields of cortical cells involved in the analysis of local motion cross the vertical midline of the visual field to a limited extent. We conclude that global motion detectors that integrate motion from both halves of the visual field play a role in shifting the perceived position of the FOE and that local motion interactions may be sufficient, but are not necessary for the optic flow illusion to occur.

Adult↗

PubMed2005

Distributions of alternation rates in various forms of bistable perception.

Studying the temporal dynamics of bistable perception can be useful for understanding neural mechanisms underlying the phenomenon. We take a closer look at those temporal dynamics, using data from four different ambiguous stimuli. We focus our analyses on two recurrent themes in bistable perception literature. First, we address the question whether percept durations follow a gamma distribution, as is commonly assumed. We conclude that this assumption is not justified by the gamma distribution's approximate resemblance to distributions of percept durations. We instead present two straightforward distributions of reciprocal percept durations (i.e., rates) that both easily surpass the classic gamma distribution in terms of resemblance to empirical data. Second, we compare the distributions arising from binocular rivalry with those from other forms of bistable perception. Parallels in temporal dynamics between those classes of stimuli are often mentioned as an indication of a similar neural basis, but have never been studied in detail. Our results demonstrate that the distributions arising from binocular rivalry and other forms of bistable perception are indeed similar up to a high level of detail.

Attention↗

PubMed2005

Manipulating saccadic decision-rate distributions in visual search.

The Gaussian shape of reciprocal latency distributions typically found in single saccade tasks supports the idea of a race-to-threshold process underlying the decision when to saccade (R. H. Carpenter & M. L. Williams, 1995). However, second and later saccades in a visual search task revealed decision-rate (=reciprocal latency) distributions that were skewed Gamma-like (E. M. Van Loon, I. T. Hooge, & A. V. Van den Berg, 2002). Here we consider a related family of Beta-prime distributions that follows from strong competition with a signal to stop the sequence, and is described by two parameters: a fixate and saccade threshold. In three saccadic search experiments, we tried to manipulate the two thresholds independently, thereby expecting change in shape and mean of the reciprocal latency distribution. Interestingly, rate distributions for later saccades were significantly better fit by Beta-prime than by Gamma functions. Increases in the distribution's skew were found with higher display density, but only for second and later saccades. First saccade rate distributions were not altered by the expected target location or by visual information presented prior to the search, but making pre-search saccades did influence both thresholds. The mean rate remained a stereotyped function of ordinal position in the saccade sequence. Our results support strong competition between two decision signals underlying the timing of saccades.

Decision Support Techniques↗