Biomedical subjects

Albertas Skurvydas

Publications and source records attributed to Albertas Skurvydas.

4 recordsLinked to original sources

PubMed2006

Dynamics of indirect symptoms of skeletal muscle damage after stretch-shortening exercise.

Healthy untrained men (age 20.4+/-1.7 years, n=20) volunteered to participate in an experiment in order to establish dynamics of indirect symptoms of skeletal muscle damage (ISMD) (decrease in maximal isometric voluntary contraction torque (MVCT) and torque evoked by electrostimulation at different frequencies and at different quadriceps muscle length, height (H) of drop jump (DJ), muscle soreness and creatine kinase (CK) activity in the blood) after 100 DJs from 0.75 m height performed with maximal intensity with an interval of 20s between the jumps (stretch-shortening exercise, SSE). All ISMDs remained even 72 h after SSE (P<0.01-0.001). The muscle experienced greater decrease (P<0.01) in torque evoked by electrostimulation (at low stimulation frequencies and at short muscle length in particular) after SSE than neuromuscular performance (MVCT and H of DJ) which demonstrated secondary decrease (P<0.01) in neuromuscular performance during the first 48 h after SSE. Within 24-72 h after the SSE the subjects felt an acute muscle pain (5-7 points approximately) and the CK activity in the blood was significantly increased up to 1200 IU/L (P<0.001). A significant correlation between decrease in MVCT and H of DJ 24-48 h after SSE on the one hand and muscle soreness registered within 24-48 h after SSE on the other was observed, whereas correlation between the other indirect symptoms of skeletal muscle damage was not significant.

Acute Disease↗

PubMed2005

New methodology in biomedical science: methodological errors in classical science.

The following methodological errors are observed in biomedical sciences: paradigmatic ones; those of exaggerated search for certainty; science dehumanisation; deterministic and linearity; those of making conclusions; errors of reductionism or quality decomposition as well as exaggerated enlargement; errors connected with discarding odd; unexpected or awkward facts; those of exaggerated mathematization; isolation of science; the error of "common sense"; Ceteris Paribus law's ("other things being equal" laws) error; "youth" and common sense; inflexibility of criteria of the truth; errors of restricting the sources of truth and ways of searching for truth; the error connected with wisdom gained post factum; the errors of wrong interpretation of research mission; "laziness" to repeat the experiment as well as the errors of coordination of errors. One of the basic aims for the present-day scholars of biomedicine is, therefore, mastering the new non-linear, holistic, complex way of thinking that will, undoubtedly, enable one to make less errors doing research. The aim of "scientific travelling" will be achieved with greater probability if the "travelling" itself is performed with great probability.

Biological Science Disciplines↗

PubMed2003

Low frequency fatigue of quadriceps muscle after sustained maximum voluntary contractions.

Immediately after sustained maximum voluntary contractions for 60 s, greater quadriceps muscle fatigue and, especially, low frequency fatigue is observed. The results of our study have shown that immediately after the exercise there was a significant (P<0.05) decrease in muscle force induced by low (20 Hz) and high (50 Hz) stimulation frequencies and maximum voluntary contractions (it is not muscle length-dependent) and it did not recover to its initial (pre-exercise) level 15 min after the end of exercise. These observations suggest the observed low frequency fatigue may consist of 2 phases: an early, rapid recovery phase (to 3 min), likely related to muscle potentiation and metabolite build-up, and a slow recovery phase, which is not dependent on metabolite levels, but is especially dependent on muscle mechanical damage. There is an increase in low frequency fatigue during a slow recovery phase and it is more pronounced when low frequency fatigue is registered at short muscle length.

Adult↗

PubMed2002

[Influence of temperature on the recovery of muscle function after performing maximal intensity exercise].

The purpose of this study was to establish the influence of temperature on quadriceps femoris muscle force, contraction and relaxation time, low frequency fatigue and muscle recovery after performing high-intensity exercise. Healthy untrained men (age 21-30 years, n = 9) gave their informed consent to take part in all experiments within the study. A high voltage stimulator (MG 440, Medicor, Hungary) was used for electrical stimulation; quadriceps muscle was stimulated through surface electrodes (9 x 18 cm) padded with cotton cloth and soaked in saline solution. The following data were measured: the force of quadriceps muscle, aroused by electrical stimulation under 1 Hz (Pt), 20 Hz (P20) and 50 Hz (P50) frequencies (the duration of each electrical stimulation series was 1 second) and maximal voluntary contraction force (MVCF). Hot water (44-45 degrees C) bath was used for muscle heating. Blood lactate concentration was measured before exercise and after 5 min. and 1 hour after performing high-intensity exercise. Two experiments with two months recreation time were carried out. The following conclusions were received: even though muscle heating increases the speed of dominating lactate in blood and increases the muscle force caused by low and high stimulation frequency, it does not influence the recovery properties of muscle contraction and relaxation during 24 hours after performing high-intensity exercise.

Adult↗