Biomedical subjects

Alberto Baldasseroni

Publications and source records attributed to Alberto Baldasseroni.

4 recordsLinked to original sources

PubMed2002

Occupational risk factors for renal cell cancer: a case--control study in northern Italy.

Relatively little is known about occupational and other risk factors for renal-cell carcinoma (RCC). Associations between RCC and occupations, exposures and other factors were investigated in a hospital-based case-control study in Bologna (central-northern Italy). Between 1986 and 1994, 324 histologically confirmed RCC cases were diagnosed at Policlinico S. Orsola-Malpighi in patients from the Province of Bologna. Corresponding control subjects admitted to the same hospital with any diagnosis except RCC were matched for sex, age, and residency. We studied the 249 cases and 238 controls for whom detailed information on occupational history, diet, smoking habits, alcohol and drug intake was obtained. At conditional logistic regression, among males (167 matched pairs), significant matched odds ratios (OR) were found, after adjusting for cigarette smoking and alcohol intake, for high body-mass index BMI (third quartile: OR, 4.91; confidence interval [95% CI], 1.56-15.5; last quartile: OR, 4.42; 95% CI, 1.48-13.18), railway workers (OR, 10.14; 95% CI, 1.46-70.17) and asbestos exposure (OR, 7.11; 95% CI, 1.46-34.51); nearly significant OR were found for managers (OR, 3.59; 95% CI, 0.82-15.59) and metal workers (OR, 2.21; 95% CI, 0.99-5.37). Among females (52 pairs), significant OR were found for BMI > 25.4 (OR, 8.46; 95% CI, 1.02-68.0). Railway workers (on or near to trains) may have increased risk of developing RCC, possibly due to asbestos exposure. Studies are required on possible risks encountered by railway (and metal) workers and by managers.

Adult↗

PubMedDate not supplied

[A survey on fatal work accidents based on Mortality Registry data: results of the Tuscany study on INAIL and RMR cases in the period 1992-2996].

Work-related deaths are important "sentinel events" of unsuccessful prevention. In Italy the most exhaustive source of such events is the National Fund for Occupational Diseases (INAIL), but the amount of cases from this source seems to be underestimated due to the fact that it refers only to cases occurred to subjects insured by the Fund. A previous survey estimated the real amount of work-related deaths 10-20% higher than that quantified by INAIL. This study evaluated the contribute of the two most important sources (INAIL and the Regional Mortality Registry of Tuscany-RMR) in estimating the number of these cases in Tuscany in the period 1992-96. Cases were identified from each source, and then it was applied a capture-recapture method to size the cases from work-related accident different from road accidents. RMR appeared to be the most exhaustive source with 72.3% completeness versus 56.4% completeness of INAIL source. Nevertheless the last one must be considered the primary source, more specific and accurate, and since few years also timely, than any other one. Work-related deaths from road accident represent 35.9% of INAIL cases but they are difficult to be identified from RMR and were not considered in this study. In conclusion the mortality data should be used for an epidemiologic surveillance system on work-related deaths not due to road accident in order to identify cases occurred to subjects not insured by INAIL (and therefore not defined by the Fund). These deaths are also important in terms of public health. Cases identified only from RMR, occurred in Tuscany in 1992-96, were 155: the vast majority occurred to farmers (mainly pensioners, and due to caterpillar upsetting), to bricklayers, to railway workers, to soldiers and to entrepreneurs.

Accidents, Occupational↗

PubMedDate not supplied

[Mussolini's fight against occupational diseases (1922-1943): Italian leadership in the production of artificial silk].

After the end of the World War I Italy's economy was predominantly rural; industrialization had taken place only in the North-Western "Milan-Genoa-Turin triangle". Technological know-how and experience in developing the production cycles were scarce. The early experience in occupational medicine had been abruptly interrupted by the war. The attitudes of the Fascist regime with regard to work protection were ambiguous: work was claimed to be a sacred source of the national wealth worth being safeguarded by the regime, but the workers' potential to antagonize the regime was seen as a constant danger to public order. This scenery is well exemplified by a case study: Viscose-Ray-on Industry developed in synchrony with Mussolini's seizing power, in the early 20s. Thanks to the initiative of some manufacturers, Italy acquired a predominant role in this sector and became the second producer after the United States. Huge factories were created and complex equipment was imported from abroad. No attention was paid to health and safety at work. The major source of risk was carbon disulphide, used as a solvent in the production of xanthogenate starting from cellulose, the raw material; which produces progressive conditions following prolonged exposure. The slowness and the substantial inertia of the Fascist regime in the protection of workers' health contrasted with the reality in the Unit States, Italy's main competitor of Italy in the production of rayon. In order to exploit masses of workers, Fascism, unlike Nazism, needed no inferior "race": social discrimination was equally effective. Modern industrial development in Italy relied on masses of semiliterate farmers originating first from the Venetian region and later (after World War II) from Southern Italy. Shortly after 1945, during the so-called "Reconstruction-period", health protection developed slowly and circumspectly. National agencies supposed to have a proactive role in prevention, such as ENPI, confirmed their role as consultant of the employers for hygiene and prevention matters. Only the workers' fight around 1970 overcame the concept of the Corporative state introduced by the Fascism.

Cellulose↗

PubMedDate not supplied

[Future prospects].

Explore the source record for details and available documents.

Epidemiology↗