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Biomedical subjects

Alejandro Aris

Publications and source records attributed to Alejandro Aris.

7 recordsLinked to original sources

Tricuspid valve replacement in the presence of an endocardial pacemaker electrode.

A technique is described to implant a mechanical tricuspid prosthesis in a patient with a previously implanted endocardial pacemaker lead. The lead was allowed to pass between two pledgeted sutures placed in the area of the septal leaflet. The patient remains asymptomatic, with a functioning pacemaker system at one year following the procedure.

Aged↗

Anabasis of PTCA.

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Angioplasty, Balloon, Coronary↗

Hemostatic herbs.

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Greece, Ancient↗

Intraaortic administration of protamine: Method for heparin neutralization after cardiopulmonary bypass.

In neutralizing heparin with intravenous protamine sulfate, hypotension may be prevented by administering the drug intraarterially. Forty patients underwent cardiac surgery with extracorporeal circulation in our hospital; each received a rapid injection of nondiluted protamine sulfate in the aortic root to reverse the effects of heparin. To maintain the blood volume at a constant level, volume expanders and inotropic drugs were avoided. The intraaortic injections ranged in duration from 0.2 min to 2.8 min, with a mean of 1.1 min. The mean systolic pressure only dropped from 92 mm Hg (SD +/- 21) before protamine injection to 85 mm Hg (SD +/- 23) after injection (p < 0.0001). In seven patients (18%), no hypotension was evident; in the remaining patients, the systolic pressure returned to preinjection values within a mean of 2.2 min. Coagulation was observed within 3 to 4 min (mean = 2.2 min) after the initiation of injection. This study indicates that intraaortic administration of protamine is a rapid and safe technique for heparin reversal after cardiopulmonary bypass.

Journal Article↗