Biomedical subjects

Aleksandras Antusevas

Publications and source records attributed to Aleksandras Antusevas.

4 recordsLinked to original sources

PubMed2006

[Resistance of Staphylococcus aureus isolated from burn wounds to antibiotics].

OBJECTIVE: To determine the colonization rate of Staphylococcus aureus in burn wounds and to assess the variation in the resistance of Staphylococcus aureus strains to antibiotics. MATERIAL AND METHODS: A retrospective study of 72 patients with burn wounds was carried out during 1997 and 2003. Specimens taken from burn wounds at first, fifth, and later every seventh day of hospitalization were placed in transport medium. Isolates were grown on mannitol salt agar. Cultures of Staphylococcus aureus were determined using plasmacoagulase and DNA-ase tests. The resistance of Staphylococcus aureus strains to penicillin, oxacillin, ceftazidime, vancomycin, gentamicin, kanamycin, tobramycin, doxycycline, ciprofloxacin, cefepime, fusidic acid, and clindamycin was determined. The isolated strains of Staphylococcus aureus were tested for resistance to methicillin by performing a disc diffusion method using commercial discs (Oxoid) (5 microg methicillin per disk and 1 microg oxacillin per disk). RESULTS: During 1997-2003, a total of 221 Staphylococcus aureus cultures were isolated from burn wounds. More than one-fourth of all isolated Staphylococcus aureus strains (25.3%) were resistant to methicillin; 64% of methicillin-sensitive Staphylococcus aureus strains were resistant to clindamycin and 28-30% - to gentamicin and kanamycin. The resistance rate of methicillin-resistant Staphylococcus aureus strains to doxycycline, clindamycin, oxacillin, tobramycin, gentamicin, and kanamycin was 78.5-98%. Majority of Staphylococcus aureus strains were non-susceptible to ceftazidime (91-100%); the rate of resistance to clindamycin decreased from 99% to 36%, (p<0.05) and to ciprofloxacin - increased from 55-65% to 81% (p<0.05). CONCLUSIONS: Staphylococcus aureus was the most prevalent pathogen isolated from burn wounds. On the first day of hospitalization Staphylococcus aureus isolates were obtained from 25.3% of patients; 12.5% of patients with burn wounds had methicillin-resistant Staphylococcus aureus at the end of the first week of hospitalization and 66% of patients--after two weeks and later. The resistance of methicillin-susceptible Staphylococcus aureus to gentamicin, tobramycin, and clindamycin decreased. The resistance of methicillin-resistant Staphylococcus aureus to clindamycin decreased and to ciprofloxacin--increased.

Anti-Bacterial Agents↗

PubMed2005

[Prevention of intestinal ischemia after abdominal aortic reconstructive surgery].

UNLABELLED: The aim of this study was to estimate rate of intestinal ischemic complications after abdominal aortic reconstructive surgery, to evaluate risk factors and to provide means of prevention of complication. MATERIAL AND METHODS: Study group consisted of 172 patients who underwent aortic reconstruction in 2000-2003 in the Department of Vascular Surgery of Kaunas University of Medicine Hospital. Six patients underwent intestinal ischemia in the postoperative period, i. e. 3.5%; four of them died. This indicated that 13% of patients died after abdominal aortic surgery. Ninety-four patients underwent operation for aortoiliac occlusive disease, colon ischemia occurred in 1 case (1.1%). Seventy-eight patients underwent abdominal aortic aneurysm; 33 patients -- ruptured aneurysm, and 45 -- aneurysm without rupture. In ruptured abdominal aortic aneurysm group with III degree colon ischemia there were 3 cases (9.1%); 2 of them died, which formed 11% of all deaths in this group. In the group of non-ruptured abdominal aortic aneurysm with III degree colon ischemia there were 2 cases (4.4%). Both patients died, which formed 50% of all deaths in this group. For all patients operated for abdominal aortic aneurysm, a. mesenterica inferior stump pressure was evaluated. In case of stump pressure 50 mmHg and more a. mesenterica inferior was ligated. If pressure was lower than 50 mmHg a. mesenterica inferior was reimplanted into vascular graft. Forty-nine reconstructions of a. mesenterica inferior were made in abdominal aortic aneurysm group: 25 in ruptured cases, and 24 in non-ruptured cases. Despite the fact that a. mesenterica inferior was reconstructed, 2 patients had colon ischemia after this reconstruction in the group of ruptured aneurysm. In the group of non-ruptured aneurysm, colon ischemia developed only after ligation of a. mesenterica inferior. We conclude that a. mesenterica inferior is very important for normal circulation of left colon. Correct evaluation of preoperative aortography, correct operative strategy, and reimplanted a. mesenterica inferior if it is necessary -- are the main means of colon ischemia prevention after abdominal aortic surgery.

Aged↗

PubMed2003

[The surgical treatment of acute ischemia of the lower limb].

OBJECTIVE: To analyze the surgical treatment strategy of lower limb acute ischemia and its results in the Department of Vascular Surgery of Kaunas University of Medicine Hospital in the period from 1999 to 2001. MATERIAL AND METHODS: While collecting the data retrospectively there has been determined, that due to the acute ischemia of the limbs there have been operated 244 patients (12.2% of all treated arterial patients). Because of the lower limb acute ischemia there have been operated 142 (7.1%) patients. All embolism and thrombosis have been approved with the operation findings. The comparison of quantitative values was done according to the Student parameter. RESULTS: The acute ischemia in the leg has been caused by: embolism - for 76 (53.5%) patients, acute thrombosis - for 66 (46.5%). Heart diseases have been ascertained in embolism group for 22.4% of patients, in acute thrombosis group - for 6.1%. The localities of embolism - the popliteal artery for 44.7% and femoral artery for 32.9%, acute thrombosis - in the femoral artery for 37.9% and iliac artery for 22.7%. Men experience the acute thrombosis more often (3.5:1), p<0.0001, and women - embolism (2.5:1), p<0.0001. Embolism has been treated with embolectomy, and acute thrombosis with thrombectomy, thrombendarterectomy and the bypass operations. There have been made 4.9% of great amputations, rescued 96.1% of lower limbs with the features of acute ischemia. Total death rate - 4.2%. CONCLUSIONS: The acute ischemia in the leg because of embolism was for 76 patients, the acute thrombosis - for 66 patients. Lower limbs embolism of arteries is more common for women, p<0.0001, acute thrombosis for men, p<0.0001. The death rate is higher in women group with acute ischemia than men, (p=0.1198) and in men group with acute ischemia in the lower limb there are made more great amputations (p=0.04250).

Acute Disease↗

PubMed2002

[Ruptured abdominal aortic aneurysm].

Rupture of the abdominal aortic aneurysm is a high lethal risk pathology, which requires precise diagnosis and urgent and efficient surgical treatment. Despite improved diagnostic capabilities (echoscopy, in specialized departments--angiography, computed tomography, magnetic nucleus resonance), mortality related to this pathology remains high in intensive care units. In the present article data concerning prevalence and clinical outcomes of the rupture of the abdominal aortic aneurysm for 1999-2001 is presented in detail. During this period 22 patients have undergone surgery due to abdominal aortic aneurysm rupture. Described are most prevalent complications, mortality rates and causes, analyzed are treatment strategy and tactics.

Aged↗