Time delays in coupled multibubble systems.
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Letter↗
Biomedical subjects
Alexander A Doinikov
Publications and source records attributed to Alexander A Doinikov.
Cavitation bubble-driven cell and particle behavior in an ultrasound standing wave.
The behavior of human erythrocytes and 1-microm-diameter fluorescent latex beads in the presence of Optison contrast agent in a single half-wavelength (lambda/2) ultrasound standing wave (USSW) resonator has been studied. The particle movements were observed with an epi-fluorescent microscope and the velocity of the particles and cells was measured by particle image velocimetry (PIV). Acoustic emissions were monitored with a microphone and a spectrum analyzer. Optison contrast agent disintegrated immediately on exposure to ultrasound of 0.98-MPa acoustic pressure amplitude or higher in a chamber driven at its resonance frequency of 1.56 MHz. A discrete cloud of active microbubbles, detected at the pressure node plane, disappeared gradually and was completely lost within 15 s. The microscopy showed three-dimensional regions of circulation of both 1-microm tracer particles and erythrocytes in planes perpendicular to the pressure node plane. A numerical simulation showed that, for parameters that conform to the experimental conditions, a bubble of a subresonance size moves towards and translates about a pressure node plane. This result is in agreement with the experimental observation that the particle and cell circulation is induced by the presence and/or translational motion of microbubbles at the pressure node plane.
Acoustics↗
Viscous effects on the interaction force between two small gas bubbles in a weak acoustic field.
The relative motion of two gas bubbles in an acoustic field is investigated by calculating the time-averaged interaction force known as the secondary Bjerknes force. The surrounding medium is assumed to be an incompressible viscous liquid and the separation distance between the bubbles much larger than their radii. A refined formula for the interaction force is derived, which allows for translational oscillations of the bubbles, the vorticity of the linear scattered field, and acoustic streaming. The boundary condition of slippage on the gas-liquid interface is assumed. It is shown that viscous effects can cause small bubbles, driven well below resonance, to repel each other within a relatively wide parameter range. This result discloses a significant boundedness of the classical Bjerknes theory according to which bubbles of this sort are capable of mutual attraction alone.
Journal Article↗