Biomedical subjects

Ali Acar

Publications and source records attributed to Ali Acar.

4 recordsLinked to original sources

PubMed2004

Serum TNF-alpha, IL-6, lupus anticoagulant and anticardiolipin antibody in women with and without a past history of recurrent miscarriage.

OBJECTIVE: The aim of the this study was to investigate Lupus Anticoagulan (LA), Anticardiolipin Antibody (ACA), Tumor Necrosis Factor-alpha (TNF-alpha) and Interleukin-6 (IL-6) serum levels in 40 pregnant and 20 nonpregnant. MATERIALS AND METHODS: The women were divided into three groups. The first group consisted of 20 pregnant women of less than 20 gestational weeks and a past history of habitual abortion . The second group consisted of 20 non pregnant patients with a past history of habitual abortion. The third group consisted of 20 healthy non pregnant women. RESULT: LA was found in only one patient in the Group 2. ACA Ig G positivity were found 1 patient in the Group 1, 3 patients Group 2 and 1 patient in Group 3. Mean ACA IgG was highest in the Group 2. High serum TNF-alpha levels were found in the 12 (60%), 6(30%) and 2 (10%) women in the Groups 1, 2, and 3, respectively. Significant difference were found for TNF-alpha among the groups (P<0.05). The highest level of TNF-alpha was found in the Group 1 and the lowest in the Group 3. There were statistically significant differences for IL-6 among the three groups (P>0.05). CONCLUSION: We propose that cytokines especially TNF-alpha was found to be related to the pregnancy loss.

Abortion, Habitual↗

PubMed2003

Methotrexate for cervical pregnancy. A case report.

BACKGROUND: The incidence of cervical pregnancy is 1:1,000-95,000 pregnancies and represents < 1% of all ectopic pregnancies. Evacuation of the pregnancy by curettage does not always stop the bleeding because there is little contractile muscle in the cervix. If there is uncontrollable bleeding, hysterectomy is necessary. In selected cases, nonsurgical management offers high success rates. Among medical treatments, the most common is systemic or local administration of methotrexate. CASE: A 36-year-old woman, gravida 2, para 2, presented with vaginal bleeding and subacute pain in the lower abdomen. The patient was 7 weeks' pregnant according to her last menstrual period. Transvaginal ultrasonography showed a gestational sac of approximately 5 weeks' gestational age implanted in the wall of the cervix. Fifty milligrams of methotrexate was injected into the gestational sac and another 50 mg administered intramuscularly. The hCG level decreased continuously and was no longer detectable after 35 days. CONCLUSION: The use of methotrexate for cervical pregnancy is safe and effective and preserves fertility.

Abortifacient Agents, Nonsteroidal↗

PubMed2002

Ovarian osteoma.

Ovarian osteoma is very rare pathology. In this case report, an ovarian osteoma is presented.

Adult↗

PubMed2002

Can myomectomy be performed during pregnancy?

OBJECTIVE: To evaluate the effectiveness, safety, complications and outcome of pregnancy after myomectomy performed during pregnancy. MATERIAL AND METHODS: Five pregnant women with myomas requiring operation because of severe abdominal pain were included in the series at the Department of Obstetrics and Gynecology, Selçuk University Faculty of Medicine between October 1, 1996 and February 24, 2001. The patients were controlled with ultrasonography and cardiotocography every month up to 32 gestational weeks and then every 2 weeks. Cesarean section was performed on all patients at 37-40 weeks. Complications and fetoneonatal outcome were recorded. RESULTS: The mean age of the patients was 31.4 +/- 3.5 years. The mean parity was 1.4 +/- 1.6. The median gestational age at the time of myomectomy was 17.8 +/- 3.4 weeks. The mean size of the myomas was 14.0 +/- 3.8 cm. The main symptom of all patients was severe abdominal pain in spite of analgesic medication. The mean duration of the operation was 40.0 +/- 7.9 min. The mean blood loss was 280.0 +/- 83.6 ml. The mean number of myomas removed was 2.8 +/- 1.3. CONCLUSION: Myomectomy during pregnancy can be performed if necessary.

Adult↗