Biomedical subjects

Alicia Fernández-Sein

Publications and source records attributed to Alicia Fernández-Sein.

3 recordsLinked to original sources

PubMed2006

Infection-associated hemophagocytic syndrome: a rare potentially fatal complication of systemic infection. Report of three cases.

Infection-associated hemophagocytic syndrome is a rare, potentially fatal complication of systemic infection. It occurs most often in immunocompromised patients associated with a viral infection but the spectrum of conditions have been broadened to include virtually every type of infectious pathogen, malignancy and immunosuppressive therapy. We present three pediatric patients with a similar clinical history of pancytopenia, hepatosplenomegaly, and acute liver failure, and discuss the autopsy findings.

Autopsy↗

PubMed2005

Renohepaticopancreatic dysplasia: diagnostic dilemma.

We present the case of an eighteen day old baby boy hospitalized with an abdominal mass, renal insufficiency and jaundice. Multiple radiographic, radionuclear and surgical interventions were required to diagnose renohepaticopancreatic dysplasia, also known as Ivemark II syndrome. In spite of aggressive intensive care support, the patient developed multisystemic organ failure and died. Clinical presentation and autopsy findings are presented.

Acute Kidney Injury↗

PubMed2002

Pediatric experience with brain death determination.

A retrospective study of the experience at the University Pediatric Hospital during a six-year period when 2529 patients were admitted to the Pediatric Intensive Care Unit (PICU) and 80 were diagnosed with brain death. Etiologic causes, age and sex distribution and use of confirmatory studies were evaluated. The specific criterias for brain death determination in children are discussed and it was found that 3.1% of all the admissions to PICU were diagnosed with brain death. This diagnosis was most common in the 6 to 12 year old children (35%) and in infants younger than 2 years of age (30%). Trauma accounted for 41.0% of the cases. In babies less than 6 months of age, 71.4% were battered. Only 11% accepted organ donation.

Brain Death↗