Identification of the Novel MICA*002:01:30 Allele in a Haematopoietic Stem Cell Donor From India.
MICA*002:01:30 differs from MICA*002:01:03 by a transition of C > T at position 3678 in intron 1.
Humans↗
Biomedical subjects
Alka Khadwal
Publications and source records attributed to Alka Khadwal.
Identification of KIR3DL1*0080105, KIR3DL1*0150224 and KIR2DL4*060 by Next Generation Sequencing.
The novel KIR3DL1*0080105, KIR3DL1*0150224, and KIR2DL4*060 is identified in healthy individuals from the Indian population.
Humans↗
Persistent coagulopathy in snake bite.
Bleeding diathesis is a cardinal feature of viperine bite, which has been thought to last not more than 24 hours. There is scarcity of literature about prolonged bleeding disorder in snake envenomation. Various explanations suggested in the literature include-temporary decrease in antivenin levels, rapid elimination of antivenin from circulation or continuous release of unneutralised venom from the envenomated site. Two children with prolonged coagulopathy lasting for more than a week, correction of which required more than 300 ml of antisnake venom are reported here.
Antivenins↗
Neonatal transfusion malaria requiring exchange transfusion.
Transfusion-acquired malaria in a neonate is uncommon and factors such as drug resistance and concomitant G6PD deficiency can cause treatment difficulties. We report a 26-day-old premature infant with chloroquine-resistant malaria who underwent exchange transfusion. The aim was to correct anaemia, decrease parasitaemia and remove G6PD-deficient cells to allow successful use of quinine.
Anemia↗
Acute lymphoblastic leukemia presenting as cyclic neutropenia.
Clinical and laboratory parameters usually allow an easy diagnosis of acute lymphoblastic leukemia in most cases. Difficult arises, however, when presentation is atypical. A young child with membranous tonsillo-pharyngitis secondary to an isolated neutropenia is reported. The neutrophilic count later showed fluctuations reminiscent of cylic neutropenia. Bone marrow examination revealed the true nature of underlying disorder.
Bone Marrow↗