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Biomedical subjects

Allen M Seiden

Publications and source records attributed to Allen M Seiden.

3 recordsLinked to original sources
PubMed2004

Postviral olfactory loss.

A viral upper respiratory infection is one of the most commonly identified causes of olfactory loss, accounting for 20% to 30% of patients in most series. Given the ubiquitous nature of upper respiratory infections, it is not clear what predisposes some patients to develop this complication. Studies have demonstrated degenerative changes within the olfactory epithelium, the severity of which seems to correlate with the severity of olfactory loss. Although no available therapy has proved effective, long-term follow-up data have found that approximately two thirds of these patients eventually experience a significant improvement in their olfactory function.

Acute Disease↗
PubMed2003

The clinical effects of hyaluronic acid ester nasal dressing (Merogel) on intranasal wound healing after functional endoscopic sinus surgery.

OBJECTIVES: We sought to determine the efficacy of MeroGel, an absorbable hyaluronic acid nasal dressing (HA) in reducing synechia after functional endoscopic sinus surgery (FESS) compared with Merocel, a nonabsorbable packing (NAP) requiring removal. METHODS: We conducted a blinded, randomized, controlled trial of 37 patients requiring bilateral FESS for chronic sinusitis. Patients were randomized to placement of HA within the right or left middle meatus and NAP on the other side. Patients were evaluated at 2, 4, 6, and 8 weeks postoperatively. RESULTS: Blinded evaluation revealed 5 patients (14%) with synechia at last follow-up: 3 sides (8%) with HA and 3 (8%) with NAP. Thirteen patients (35%) had synechia at any visit, 10 sides (27%) with HA and 9 (24%) with NAP. Seven patients (19%) required lysis of synechia, 5 sides (14%) with HA and 3 (8%) with NAP. CONCLUSION: We found no statistically significant difference between HA and NAP dressings.

Bandages↗