PubMed Health⌕ Search

Biomedical subjects

Amita Aggarwal

Publications and source records attributed to Amita Aggarwal.

41 records · Page 3Linked to original sources
PubMed2002

Multifocal tubercular dactylitis in an adult.

Musculoskeletal tuberculosis (TB) is a rare manifestation of TB comprising 1%-3% of all cases. We describe a patient who had multiple manifestations of skeletal TB, including spondylitis, dactylitis, and Poncet's disease. The unusual features include multifocal dactylitis, widespread disease in the absence of any risk factor like HIV infection or immunosuppressive treatment, and absence of pulmonary lesion. Treatment with appropriate drugs, using 4 agents for the first 2 months, led to complete recovery. TB can rarely present in an unusual way but is very important to recognize, as with treatment it still carries a good prognosis.

Journal Article↗
PubMed2002

Does cyclophosphamide benefit relapsing thrombotic thrombocytopenic purpura?

Thrombotic thrombocytopenic purpura (TTP) is a rare disease. A high index of suspicion is required for early diagnosis and treatment. It can present in acute as well as chronic forms. Cyclophosphamide has been reported to be beneficial in relapsing TTP. Herein a case of acute TTP evolving into relapsing phase of the disease is presented. Cyclophosphamide in our case achieved partial remission without the need for plasma exchange therapy. The rationale of cyclophosphamide in management of relapsing TTP is discussed.

Adult↗
PubMedDate not supplied

Physical, psychosocial and economic impact of rheumatoid arthritis: a pilot study of patients seen at a tertiary care referral centre.

BACKGROUND: Rheumatoid arthritis is associated with marked physical disability. In addition, it has an impact on patients' psyche and social well-being, and entails a major financial burden. The impact of the disease in different cultural and social backgrounds is varied. Limited data are available from India on this aspect. METHODS: Patients with rheumatoid arthritis satisfying the 1987 modified American College of Rheumatology criteria were included. Besides demographic data, functional impact was assessed using the Health Assessment Questionnaire (HAQ). The psychosocial impact was measured using the medical outcomes study short form 36 (SF-36) with minor modifications. Data on direct and indirect health costs were collected by direct interview. RESULTS: The mean age of 101 patients (90 women) was 43.2 years and mean duration of disease was 8 years. Their mean (SD) HAQ score was 0.97 (0.69) with 8 patients having scores > 2. On the SF-36 scale (0-100) the mean (SD) score for various domains were: physical functioning 49.90 (28.55), social functioning 55.51 (20.59), role limitation due to physical problems 32.67 (41.34), role limitation due to emotional problems 47.54 (40.08), mental health 47.36 (7.99), general health perception 52.38 (8.30), energy and vitality 58.56 (6.09), and bodily pain 49.26 (18.87). The summary score for the physical component was 37.95 (9.03) and for the mental component it was 47.71 (4.81). While the physical component summary score had excellent negative correlation with the HAQ score (r = -0.84), correlation with the mental component summary score was poor (r = 0.32). The annual average total cost burden per patient was Rs 16 758, of which Rs 11 617 (67%) was spent on health services and the rest on non-health services (travel, home help and loss of wages). CONCLUSION: Rheumatoid arthritis causes significant physical and social disability besides being an economic burden. Indian patients had good scores for mental and social health suggesting good family support systems or reluctance to express their feelings despite physical disability.

Activities of Daily Living↗