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Biomedical subjects

Amulya K Saxena

Publications and source records attributed to Amulya K Saxena.

10 recordsLinked to original sources

Experience with management of anterior abdominal wall defects using bovine pericard.

During 5 years from 1999 until 2003, our experience with 29 (100%) neonates managed for anterior abdominal wall defects is presented. Twenty-one (72%) neonates presented with gastroschisis and 8 (28%) neonates with giant omphaloceles. The male:female ratio was almost equal in gastroschisis (1:1) while a male predominance was observed in omphaloceles (6:1). A primary closure of the defect was possible in 5 (17%) cases and a single patch along with skin closure was achieved in a further 9 (31%) cases. In 15 (52%) neonates the defect was large and two patches were employed to sufficiently cover the defect. All patients (97%), except one (mortality due to extreme prematurity), were managed successfully. Depending upon the size of the defect and the metabolic condition of the neonate, the defect closure was completed after a mean of 85.7 days. Special protocols were created to manage the bovine pericard patches, which behaved differently to lyophilized dura patches previously used at our center. Integration of the patches was successful in 28 (97%) neonates; however, one neonate with gastroschisis presented significant challenges in the management. Bovine pericard patches are optimal biomaterials for the closure of anterior abdominal wall defects in gastroschisis and omphaloceles.

Abdominal Wall↗

Laparoscopic resection of solitary congenital liver cyst in a neonate.

Solitary congenital liver cysts are a rare finding and present a challenge in the diagnosis. Routine prenatal ultrasounds confirmed the presence of an isolated cystic mass in the upper abdominal cavity of a fetus during the third trimester of gestation. Ultrasound examination performed after birth confirmed the presence of a floating cyst in the upper abdomen. Laparoscopy was performed on the 12th day to confirm the diagnosis using a 2.7 mm scope and instruments. Using a monopolar hooked cautery, the cyst was resected free from the liver surface without any complication. The postoperative course was uneventful. Histopathologic analysis demonstrated a true liver cyst with a mesothelial lining and hepatic residues. To our knowledge, this is the first case reported in literature where a solitary liver cyst was resected using minimal invasive techniques in a newborn.

Cysts↗

Look twice before you clamp: decapitation of an omphaloenteric duct. A case report.

OBJECTIVE: To report a case of accidental decapitation of a persistent omphaloenteric duct (POD) in congenital hernia of the umbilical cord in a newborn male. CASE PRESENTATION AND INTERVENTION: The newborn was transferred to an intensive care unit, where under closer inspection the diagnosis of an omphalocele was presumed. Surgical exploration at our Pediatric Surgical University Clinic revealed a clamped and decapitated POD in the umbilical cord. The decapitation had gone unnoticed due to severe asphyxia resulting from meconium aspiration encountered at the time of delivery. Using general anesthesia, the clamp was removed under sterile conditions. The decapitation of the POD in the herniated umbilical cord was confirmed at this time. The severed intestine was sutured and closed using 5-0 Vicryl sutures. The further course was uneventful. CONCLUSION: Herniation of the umbilical cord at the time of birth by intestinal loops or POD is rare, but caution should be taken by midwives before clamping in order to avoid the type of injury seen in this case.

Hernia, Umbilical↗

Giant pedunculated lipofibroma of the elbow.

Lipofibromas are rare hamartomatous lesions almost exclusively involving the medial nerve and have been reported to date only in the adult population. The case of a giant pedunculated lipofibroma involving the radial nerve in the elbow of a 1-year-old child is presented.

Female↗

Laparoscopic suture rectopexy for rectal prolapse in a 22-month-old child.

We present the case of a 22-month-old female child who presented with severe recurrent rectum prolapse. The patient was successfully managed using the laparoscopic simple suture rectopexy approach with 5-mm instruments employing two 3-0 nonabsorbable sutures on either side of the rectum to secure it to the presacral fascia. There was no blood loss, and the procedure was completed without complication. The child was followed up for a period of 24 months with good results.

Digestive System Surgical Procedures↗

Unusual case of needle embodiment in talar neck.

An unusual case of a needle head injury, with deep embodiment of the needle head in the neck of the left talus bone is presented. The needle head was removed at our centre after two previous unsuccessful surgical attempts at other hospitals. The mechanism of trauma and the surgical procedure has been described.

Child↗

Gastroschisis: a 15-year, single-center experience.

70 cases of gastroschisis (GS) were surgically treated at the Pediatric Surgical University Clinic, Münster, from 1984 through 1998. The defect occurred more frequently in males (44) than females (26). The average birth weight was 2,383 g and mean gestational age 36.8 weeks. 9 infants (12.9%) were delivered vaginally and the rest (87.1%) by cesarean section; 34 of the 61 (55.7%) cesarean sections were done solely for prenatal ultrasonic identification of the abdominal-wall defect. 10 infants (14.3%) underwent primary closure; in 19 (27.1%) primary closure of the skin was possible, however, a single solvent-dried dura (SDD) graft was required for fascial enlargement. The remaining 41 infants (58.6%) had extensive defects and required two grafts for optimal closure. 22 patients (31.4%) had associated anomalies, the most common being bowel atresias and undescended testis. 14 (20%) required secondary laparotomies because of bowel-associated complications and 1 (1.4%) for a urinary-bladder perforation. 11 patients (15.7%) had non-bowel-associated complications. The average postoperative tracheal intubation time was 3.9 days and the average hospital stay was 75.6 days. The overall mortality was 2.8%. No major complications associated with SDD implants were encountered; only 4 patients (5.7%) had minor complications such as local inflamation and infection and were managed conservatively. The present data support the employment of SDD implants as acceptable biomaterial for the repair of large GS defects.

Abnormalities, Multiple↗