PubMed Health⌕ Search

Biomedical subjects

Amy Borenstein Graves

Publications and source records attributed to Amy Borenstein Graves.

11 recordsLinked to original sources

Normative data for elderly African Americans for the Stroop Color and Word Test.

The Stroop Color and Word Test is a measure of executive function that is commonly used in neuropsychological evaluations, but for which there are currently no normative date for elderly African American individuals. The present investigation examined the influence of demographic characteristics on this measure in a community-dwelling sample of 236 elderly African American adults (60-84 years of age). Age, education, gender, and the education by gender interaction were found to affect performance on the Stroop Color and Word Test tasks. Based on these results, normative tables for Stroop Color and Word Test scores, stratified by age and with score adjustments for education and gender, are provided.

Black or African American↗

Effects of the use of alcohol and cigarettes on cognition in elderly African American adults.

In this study we examined the independent and interactive effects of lifetime patterns of drinking and smoking on cognitive performance in elderly African Americans. A sample of 230 individuals with varying histories of alcohol and cigarette use was drawn from the Hillsborough Elder African American Life Study, a community-based, cross-sectional study of older adults aged 60 to 84. Dependent variables were the results of a neuropsychological battery that provided measures of general cognitive ability, executive function, and memory. Specifically, our study addressed (1) whether individuals with a lifetime history of sustained smoking and/or drinking show lower levels of cognitive performance in comparison to lifetime abstainers, (2) whether cumulative lifetime doses of alcohol or cigarettes, or of the two substances in interaction, have an effect on cognition, and (3) whether individuals who have histories of periodic, intense use of either alcohol or cigarettes show lower levels of cognitive performance in comparison to lifetime abstainers. When significant results were obtained, effect sizes were small, not exceeding 5% of the variance. A single exception occurred for the intensity analyses, in which drinking explained approximately 16% of the variance in global cognitive ability after adjusting for the contributions of control variables. In these analyses, drinking was found to have a U-shaped effect on global cognitive ability and total acquisition in the memory trials. Specifically, moderate users performed at a lower level than abstainers or heavy users, who did not differ from each other.

Black or African American↗

3MS normative data for elderly African Americans.

The Modified Mini-Mental State Examination (3MS) is an expanded and modified version of the Mini-Mental Status Exam (MMSE). Although the MMSE has achieved widespread clinical use as a brief cognitive screen, the utility of the measure to ascertain cognitive impairment is constrained by a limited set of abilities sampled, a narrow range of possible scores, floor and ceiling effects, and by a paucity of normative data for use with older adults from ethnically diverse backgrounds. Research demonstrates that the reliability, validity, and sensitivity of the 3MS are superior to that of the MMSE in detecting cognitive impairment. To date there has been minimal research investigating the usefulness of the 3MS with African American older adults. The current study examined the influence of demographic characteristics on the 3MS in a community-dwelling sample of 238 African American older adults (60-84 years). Age, gender, and education accounted for moderate amounts of variance in 3MS performance. Based on these results, normative tables for 3MS scores, stratified by age and with score adjustments for education and gender, are provided.

Black or African American↗

Alcohol, aging, and cognitive performance: a cross-cultural comparison.

This study investigated the relationship between alcohol consumption and cognitive performance in two culturally diverse community-based populations. METHODS. A cross-sectional analysis was used including Japanese Americans (n = 1,836) and Caucasians (n = 2,581) aged 65 and older. Cognitive performance was measured using the Cognitive Abilities Screening Instrument (CASI) (0 to 100 point scale) and reaction time. RESULTS. Multivariate analysis revealed significant cultural and gender differences with cognitive performance. Compared to abstainers, Caucasian drinkers scored higher than Japanese American drinkers on the CASI (adjusted means = 93.4 versus 91.6). In contrast, Japanese American drinkers scored faster than Caucasian drinkers on choice reaction time (adjusted means = 505 versus 579 milliseconds). DISCUSSION. Results showed that current drinking was associated with better cognition in both the Caucasian and Japanese American groups. Longitudinal studies are needed to support the possible protective effects of alcohol on cognition and explore whether culture may modify this apparent benefit.

Age Factors↗

Older adults and functional decline: a cross-cultural comparison.

BACKGROUND: The study was conducted to examine the relationships between functional decline, health risk factors, lifestyle practices, and demographic variables in two culturally diverse, community-based samples of White and Japanese American older adults. DESIGN: The study was an analysis of data from two ongoing studies of aging and dementia in King County, Washington. Functional status at baseline was evaluated, and factors associated with functional decline over a 4-year follow-up period were identified. The sample included 1,083 Japanese American and 1,011 White cognitively intact, community-dwelling adults aged 65 and older, who had no functional limitations at baseline and participated in at least one follow-up examination. RESULTS: In 4 years of follow-up, 70% of the subjects reported no increase in functional limitation, and fewer than 5% of subjects declined in five or more activities. Risk factors associated with functional decline included increased age, female gender, medical comorbidity (particularly cerebrovascular disease, arthritis, and hypertension), elevated body mass index, poorer self-perceived health, and smoking. Depression and diabetes were also significant for persons with the greatest functional decline over the 4-year follow-up. Japanese speakers were significantly less likely to decline over the follow-up period than White or English-speaking Japanese American subjects. However, Japanese speakers were more likely to discontinue participation during the follow-up period, and may also have been more likely to underreport symptoms of functional decline. CONCLUSIONS: The present study provides further support that healthy lifestyle practices and prevention of chronic disease are important for maintaining functional independence in older adults. Japanese-speaking subjects were less likely to decline over time, although this could be due in part to differential dropout and reporting bias. These findings have important implications for the design and interpretation of longitudinal studies of older adults. Researchers interested in the effects of ethnicity on health and aging should be cognizant of differences in recruitment and enrollment strategies among studies, and the ways in which these affect study findings. This study also demonstrates the importance of devoting adequate resources to minimize dropouts, and of including measures of health and functioning that are culturally equivalent and less reliant on self-report data.

Aged↗

Effects of the use of alcohol and cigarettes on cognition in elderly adults.

The objective of this study was to examine the independent and interactive effects of lifetime patterns of drinking and smoking on cognitive performance in the elderly. A sample of 395 individuals with varying histories of alcohol and cigarette use was drawn from the Charlotte County Healthy Aging Study, a community-based, cross-sectional study of randomly selected older adults of age 60 to 84. Dependent variables were the results of a neuropsychological battery that provided measures of general cognitive ability, executive function, and memory. Specifically, we examined (1) differences in performance among groups of abstainers, drinkers, and smokers, (2) the effects of lifetime drinking and smoking dose on cognition within the group of users, and (3) the effects of intensity of drinking and smoking on cognition. Potential methodological confounds, such as age, education, and medical history, were controlled by means of sampling and covariance procedures. Analyses failed to provide evidence for a beneficial J-curve or threshold effect for drinking, but did not reveal any detrimental effect. No detrimental effect of smoking was found in any analysis; nor was there any evidence of an interaction between alcohol and cigarette use on any cognitive measure.

Aged↗

Hopkins Verbal Learning Test-Revised: norms for elderly African Americans.

The Hopkins Verbal Learning Test-Revised (HVLT-R) is a memory test commonly used in neuropsychological evaluations, but for which there are currently no normative data for elderly African Americans. The current study examined the influence of demographic characteristics on HVLT-R performance measures in a community-dwelling sample of 237 African American older adults (60-84 years). Age, gender, and education accounted for moderate amounts of variance in HVLT-R performance. Based on these results, normative tables for HVLT-R scores, stratified by age and with score adjustments for education and gender, are provided.

Black or African American↗

Nonauditory determinants of self-perceived hearing problems among older adults: the role of stressful life conditions, neuroticism, and social resources.

BACKGROUND: The present study explored factors that influenced older individuals' subjective perception of hearing problems. In addition to objectively screened hearing ability, nonauditory factors such as stressful life conditions (visual impairment, chronic disease, disability, and recent stressful life events), neuroticism, and social resources were hypothesized to be predictors of self-perceived hearing problems. METHODS: These hypotheses were tested with a hierarchical regression model using a stratified sample of 425 community-dwelling older individuals (mean age = 72.2). RESULTS: Individuals with more recent stressful life events, higher levels of neuroticism, and less emotional support reported greater hearing problems after controlling for objectively screened hearing. In addition to the main effects, a significant interaction was observed between neuroticism and screened hearing, indicating that the combination of poor hearing and high neuroticism increased the level of self-perceived hearing problems. CONCLUSIONS: The findings suggest that the effects of nonauditory factors should be taken into account in the application of self-assessed measures of hearing problems.

Aged↗

The role of neuroticism in the association between performance-based and self-reported measures of mobility.

OBJECTIVE: The present study examined the role of neuroticism in older individuals' self-reports of mobility. The authors hypothesized that neuroticism would modify the association between performance-based and self-reported measures of mobility. METHOD: Using a stratified sample of 459 community-dwelling elders, a hierarchical regression analysis was conducted to assess the effects of physical performance and neuroticism in predicting self-reported mobility. RESULTS: Composite measures of lower body performance and self-reported mobility had a moderate correlation. In the regression model of self-reported mobility, neuroticism had both a direct effect and an interaction effect with physical performance. DISCUSSION: Given a certain level of physical performance, individuals who scored high on neuroticism were more likely to report disability. Also, the combination of poor performance and high neuroticism increased self-reported disability. The findings suggest that neuroticism may play an important role in subjective perception and should be considered in the interpretation of data based on self-reports.

Age Factors↗

Elderly norms for the Spot-the-Word test.

This study provides population-based normative data for healthy, community-dwelling American elderly on the Spot-the-Word test (STW). The effects of age, education, and gender on STW performance are also investigated. Given previously limited normative data for the elderly, the current norms expand the clinical utility of STW as an estimate of premorbid intelligence. Significant but small effects were found for age on STW performance. Significant and moderate effects were found for education. Therefore, normative adjustments are provided for education. Consistent with previous research, no effect was found for gender.

Journal Article↗

3MS normative data for the elderly.

The Modified Mini-Mental State Examination (3MS) was developed to overcome shortcomings of the Mini-Mental Status Exam (MMSE), specifically its narrow range of possible scores and ceiling effects. Several studies have examined the psychometric characteristics of the 3MS, showing an improvement in reliability and increased sensitivity in detecting dementia in comparison to the MMSE. Despite research supporting the favorable psychometric features of the 3MS, the clinical value of the instrument is restricted by limited normative data, especially for the elderly population. In this study, we examine the influence of demographic characteristics on 3MS scores and present descriptive data for a sample of 393 community-dwelling older adults. Normative data, based on age and with adjustments for education, are provided for clinical use.

Journal Article↗