Biomedical subjects

Amy Wenzel

Publications and source records attributed to Amy Wenzel.

17 recordsLinked to original sources

PubMed2006

Hypothesized mechanisms of change in cognitive therapy for borderline personality disorder.

Preliminary evidence suggests that cognitive therapy (CT) is effective in treating borderline personality disorder (BPD). According to cognitive theory, BPD patients are characterized by dysfunctional beliefs that are relatively enduring and inflexible and that lead to cognitive distortions such as dichotomous thinking. When these beliefs are activated, they lead to extreme emotional and behavioral reactions, which provide additional confirmation for the beliefs. It is hypothesized that a change in dysfunctional beliefs is the primary mechanism of change associated with CT. However, additional mechanisms of change are likely also at work in CT, including enhancement of skills, reduction in hopelessness, and improvement in attitude toward treatment. Each of these mechanisms is discussed in light of cognitive theory, data from an open clinical CT trial, relevant literature, and therapeutic interventions. Findings from the CT trial support the role of cognitive change during therapy and its continuation after termination.

Attitude to Health↗

PubMed2006

Autobiographical memories prompted by automatic thoughts in panic disorder and social phobia.

This study examined the retrieval of autobiographical memories when prompted by automatic thoughts that were representative of maladaptive schema content specific to 2 anxiety disorders. Participants with panic disorder (n = 20), those with social phobia (n = 22) and non-anxious participants (n = 20) indicated the first specific memory that came to mind when cued with panic-related, social phobia-related and control automatic thoughts. Panic participants retrieved memories cued with panic disorder-related automatic thoughts more quickly than social phobic and non-anxious participants, and social phobic participants retrieved memories cued with social phobia-related automatic thoughts more quickly than non-anxious participants. Relative to non-anxious participants, participants in both patient groups retrieved more anxious/worried memories when cued with automatic thoughts related to their diagnosis and more fearful memories when cued with either type of diagnosis-related automatic thought. Results indicate that panic and social phobic participants were characterized by general threat-relevant autobiographical memory biases.

Adult↗

PubMed2006

Attentional fixation in panic disorder.

According to Beck's (1988) clinical observations, patients with panic disorder describe a fixation on their distressing physical and psychological symptoms and an inability to access corrective information during panic attacks. The present study sought to evaluate empirically the notion that attentional fixation is characteristic of these patients. A subset of panic patients participating in 3 cognitive therapy clinical trials completed the Attentional Fixation Questionnaire (AFQ) at intake, during treatment and at termination. The AFQ had adequate internal consistency at all time intervals, and it correlated positively with measures of depression, anxiety and distorted cognitive content. At termination, the AFQ total score and nearly all single items decreased significantly, and patients who continued to meet diagnostic criteria for panic disorder scored higher on most items than patients who no longer met diagnostic criteria for panic disorder. These preliminary data suggest that attentional fixation is an important dimension of cognition relevant to panic disorder.

Adult↗

PubMed2005

Are there any gender differences in frequency of self-reported somatic symptoms of depression?

BACKGROUND: The purpose of this study was to evaluate whether self-reported somatic symptoms of depression, as measured by the Beck Depression Inventory-II (BDI-II), are more frequent in women than in men with major depressive disorder. METHODS: A sample of 105 male and 105 female adult psychiatric outpatients diagnosed with major depressive disorder was classified according to endorsed changes in appetite, changes in sleeping pattern, and fatigue (i.e., "somatic depression") symptoms on the BDI-II. RESULTS: The female to male ratio of somatic symptoms was approximately 2:1. Subsequent analyses found that change in appetite robustly distinguished between women and men and that fatigue partially distinguished between women and men. LIMITATIONS: The sample was largely Caucasian and composed of patients with high rates of comorbidity who presented to a service known for specializing in cognitive therapy. CONCLUSIONS: In outpatients with major depressive disorder, the higher prevalence of "somatic depression" in women is largely attributable to changes in appetite.

Adult↗

PubMed2005

Dysfunctional beliefs in panic disorder: The Panic Belief Inventory.

The Panic Belief Inventory (PBI) was developed to assess beliefs that increase the likelihood of catastrophic reactions to physical and emotional experiences in panic disorder. In the first stage of scale development, 197 panic disorder patients completed the PBI and standard self-report inventories of psychiatric symptomatology. An exploratory factor analysis yielded a 4-factor solution from which a 35-item instrument with 4 scales was constructed. The shortened measure and its scales had good internal consistency and convergent validity and moderate discriminant validity. Subsequently, 22 panic disorder patients who received cognitive therapy completed the PBI and other self-report inventories of dysfunctional cognitions at intake, 4 weeks, 8 weeks, termination, and several follow-up intervals. Results indicated that the PBI decreased significantly across treatment, with the largest decline occurring between intake and 4 weeks into treatment. The PBI correlated more strongly with dysfunctional cognitions associated with anxiety than dysfunctional cognitions associated with depression. These results provide preliminary evidence that the PBI has adequate psychometric characteristics, is useful to assess change in dysfunctional beliefs during treatment, and has the potential to advance cognitive theories of panic.

Adult↗

PubMed2005

Interpretation biases in angry and anxious individuals.

Although previous research has demonstrated many similarities between anxious and angry individuals, few studies have compared the degree and direction to which they exhibit cognitive biases in the presence of threat. The present study was a preliminary investigation of 28 angry participants, 30 anxious participants, and 26 non-angry/non-anxious participants who rated the likelihood of various explanations to account for ambiguous but potentially threatening events described in short prose passages. Angry participants rated the likelihood of positive explanations for ambiguous events lower than non-angry/non-anxious participants. Angry participants rated the likelihood of anger-related explanations higher than anxious and non-angry/non-anxious participants, and both angry and anxious participants rated anxiety-related explanations as being more likely than non-angry/non-anxious participants. Thus, both angry and anxious participants demonstrated a negative interpretation bias, although the bias was more pervasive in angry participants.

Adult↗

PubMed2005

Communication and social skills in socially anxious and nonanxious individuals in the context of romantic relationships.

This study examined differences between socially anxious and nonanxious individuals' ability to use effective communication skills and social skills in the context of romantic relationships. Socially anxious (n = 13) and nonanxious (n = 14) individuals and their romantic partners were videotaped while participating in 10-minute neutral, negative, and pleasant conversations. Regardless of the type of conversation in which they were involved, socially anxious individuals demonstrated impairment in 10 of the 11 social skill variables assessed. In negative conversations, socially anxious individuals displayed more "very negative" behaviors than nonanxious individuals, and across all conversations they displayed fewer "positive" behaviors than nonanxious individuals. Partners of socially anxious and nonanxious individuals did not differ in their communication quality. The results suggest that social anxiety is associated with deficits in relationship maintenance behavior and call for the completion of a larger study examining the interpersonal consequences of social anxiety.

Adult↗

PubMed2005

Autobiographical memory in angry and anxious individuals.

Recent studies have found that angry individuals are characterized by more pronounced attentional and interpretation biases toward threat than anxious individuals. The present study examined anger-related, anxiety-related, and neutral autobiographical memories in 35 angry participants, 33 anxious participants, and 29 non-angry/non-anxious, or healthy participants. Objective indices of autobiographical memories (i.e., retrieval latency, coding of specificity and affective tone) suggested that groups retrieved memories with similar properties. However, both angry and anxious participants rated their memories as less pleasant than healthy participants. These results indicate that memory biases are not part of the cognitive sequelae associated with anger and anxiety, although aspects of the appraisal of these personal memories are distorted.

Adult↗

PubMed2005

Anxiety symptoms and disorders at eight weeks postpartum.

Although the prevalence, risk factors for, and consequences of postpartum depression have been studied extensively, little work has examined the nature of postpartum anxiety disorders in community samples. In the present study, 147 community women completed a diagnostic interview and a battery of self-report inventories approximately eight weeks after childbirth. The rate of generalized anxiety disorder was elevated as compared to the rate in women representative of the general population. Depending on the particular domain of anxiety being considered, 10-50% of women reporting anxiety symptoms endorsed comorbid depressive symptoms. In hierarchical multiple regression analyses, different combinations of demographic and vulnerability variables predicted symptoms of somatic anxiety, social anxiety, and depression, although there were no significant predictors of worry symptoms. In addition, number of children, depression, and social anxiety predicted postpartum relationship distress. These results suggest that postpartum anxiety disorders are more common than postpartum depression and worthy of systematic study.

Adult↗

PubMed2005

Suicide attempters' reaction to survival as a risk factor for eventual suicide.

OBJECTIVE: The authors' goal was to evaluate whether suicide attempters' reaction to surviving their attempt predicted eventual suicide. METHOD: Three hundred ninety-three suicide attempters were categorized on the basis of their reaction to having survived their attempt (i.e., glad to be alive, ambivalent, wished they were dead) and were followed for 5 to 10 years to determine whether they completed suicide. RESULTS: A survival analysis found that subjects who said that they wished they had died after a suicide attempt were 2.5 times more likely to commit suicide eventually than those who were glad they survived and those who were ambivalent about the attempt. CONCLUSIONS: Suicide attempters' reaction to surviving is an important clinical variable that is easily assessed in evaluations that occur following a suicide attempt.

Adult↗

PubMed2004

Memory and interpretation of visual representations of threat in socially anxious and nonanxious individuals.

The present study was designed to replicate and extend results reported by Brendle and Wenzel (Behav. Res. Ther. 42 (2004) 155), who found that socially anxious individuals accurately recalled threat-relevant information but subsequently imposed a biased interpretation upon that same material, using more ecologically valid stimuli. Socially anxious (n=37) and nonanxious (n=47) individuals viewed two positive, two negative, and two neutral video vignettes and completed two cognitive tasks assessing memory and interpretation of factual details immediately and after 48 h. Similar to the results reported by Brendle and Wenzel (2004), socially anxious and nonanxious individuals did not differ in their memory for details that had been presented in the vignettes. However, socially anxious individuals made more negative interpretations of details included in the vignettes than nonanxious individuals, although unlike Brendle and Wenzel (2004), they did not demonstrate the tendency to make less positive interpretations. It is concluded that socially anxious individuals are characterized by interpretation biases when presented with threat-relevant information, and there is no evidence to suggest that they are characterized by memory biases for threat-relevant information.

Adult↗

PubMed2004

Differentiating between memory and interpretation biases in socially anxious and nonanxious individuals.

Although individual cognitive biases toward threat in social anxiety are well established, few studies have examined the manner in which cognitive biases work in conjunction. In the present study, socially anxious ( n = 54 ) and nonanxious ( n = 58 ) individuals read 10 passages consisting of positive social or evaluative, negative social or evaluative, and neutral content and completed two cognitive tasks assessing memory of factual details and interpretation immediately and after 48 h. Socially anxious and nonanxious individuals did not differ in their memory for details presented in the passages. However, they made less positive and more negative interpretations of details included in the passages, particularly in positive passages that were self-relevant and particularly in positive passages after the delay. After including depression, state anxiety, and trait anxiety as covariates, biased interpretation of positive passages after the time delay remained significant, but biased interpretation of the self-relevant, positive passages did not. It is concluded that socially anxious individuals are characterized by accurate memory of threatening, factual material, but that they impose a biased interpretation upon that material, especially after some time has passed.

Adult↗

PubMed2004

Autobiographical memories of anxiety-related experiences.

Ninety-nine undergraduate students retrieved three memories associated with each of the five emotional experiences: panic, trauma, worry, social anxiety, and feeling content. Subsequently, they answered 24 questions assessing properties of each memory, including the vividness and perceived accuracy of the memories and sensory, emotional, and anxiety-related experiences during retrieval. Memories were coded for affective tone and specificity. Results indicated that panic-related and trauma-related memories were rated similarly as content memories, but that they generally were associated with more imagery and emotional experiencing than worry-related or social anxiety-related memories. Participants experienced panic and worry symptoms to the greatest degree when they retrieved panic-related and trauma-related memories. All anxiety-related memories were characterized by more negative tone than content memories. Panic-related and trauma-related memories were more specific than worry-related, social anxiety-related, and content memories. These findings can explain partially why individuals with some, but not all, anxiety disorders experience enhanced memory for threatening material.

Adult↗

PubMed2003

Psychotherapy for postpartum depression: a preliminary report.

A postpartum depression treatment efficacy study showed both a mother-infant psychotherapy group and interpersonal psychotherapy to be superior to a waiting-list comparison group in reducing maternal depressive symptoms, improving mothers' perceptions of their infants' adaptability and reinforcement value, and increasing mothers' positive affect and verbalization with their infants. Clinical implications regarding the importance of early intervention for women experiencing major depression in the postpartum period and their families are discussed.

Adult↗

PubMed2003

Thought suppression in spider-fearful and nonfearful individuals.

The authors examined the suppression of spider-related thoughts in spider-fearful (n = 23) and nonfearful (n = 22) individuals. Participants were primed with vivid pictures of spiders and a story about spiders. Next, they were randomly assigned to 1 of 2 conditions: (a) suppression of thoughts associated with the previously presented spider-related stimuli or (b) free expression of any thoughts, including those related to the spider-related stimuli. All participants completed a subsequent free-expression exercise. Results indicated that spider-fearful individuals expressed thoughts about the spider-related stimuli for a longer length of time than did nonfearful individuals, particularly in the suppression condition. Participants in both groups demonstrated a rebound of thoughts associated with the spider-related stimuli following suppression. The authors propose that the priming of feared stimuli makes suppression of fear-related thoughts particularly difficult for fearful individuals, perhaps by activating a state of heightened arousal.

Adolescent↗

PubMed2002

Social phobia and the recall of autobiographical memories.

Although cognitive theories of anxiety suggest that anxious individuals are characterized by the biased tendency to recall negative experiences with perceived threat, few empirical studies have confirmed this notion. To investigate personal memories associated with threatening experiences, individuals with socio phobia (n=16) and nonanxious individuals (n=17) completed an autobiographical memory-cueing procedure. Participants were presented with 15 social threat words and 15 neutral words, and they recorded the first specific memory that came to mind. Autobiographical memories were coded for specificity and affective tone. There were no group differences in the extent to which participants retrieved specific memories. A greater number of memories cued by social threat words were characterized by negative affect in the social phobia group than in the nonanxious group. However, examination of the means suggests that this effect was small and most likely not of practical significance. It is suggested that memory biases toward threat are not a prominent part of cognitive symptoms that characterize individuals with social phobia.

Affect↗

PubMed2002

Memory bias against threat in social phobia.

OBJECTIVES: The present study examined whether social phobia is an anxiety disorder associated with a memory bias toward threat. DESIGN: Social phobic (N = 16) and non-anxious (N = 17) individuals were compared on their recall of evaluative threat and neutral prose passage content. METHOD: Participants were presented with two evaluative threat and two neutral prose passages and completed an immediate free recall task after each trial. RESULTS: Contrary to expectation, individuals with social phobia recalled a smaller percentage of units from the evaluative threat passages than non-anxious individuals. CONCLUSION: Consistent with the vigilance-avoidance theory, it is suggested that social phobia is an anxiety disorder characterized by the avoidance of elaborate processing of threatening material.

Adult↗