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Biomedical subjects

Anbo Wang

Publications and source records attributed to Anbo Wang.

At least 19 recordsLinked to original sources

Micro-air-gap based intrinsic Fabry-Perot interferometric fiber-optic sensor.

A simple intrinsic Fabry-Perot interferometric (IFPI) sensor is developed. The sensor is fabricated by two micro air gaps as reflective mirrors in a fiber to form a Fabry-Perot cavity. Theoretical and experimental studies of the sensor are described. Experimental results show that high resolution and high sensitivity can be achieved. Two structures of micro-air-gap-based IFPI sensors offer more applications than other IFPI sensors.

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Implementation of a loss-compensated recirculating delayed self-heterodyne interferometer for ultranarrow laser linewidth measurement.

Ultranarrow laser linewidth measurement using an optimized loss- compensated recirculating delayed self-heterodyne interferometer is described. An experimental setup is constructed to measure subkilohertz laser linewidths. The system parameters are optimized to obtain the best beat signals. The experimental results agree well with the theoretical analysis. Two methods of linewidth interpretation are presented and analyzed based on the experimental results. It is proved that a loss-compensated recirculating delayed self-heterodyne interferometer is an effective tool for measuring an ultranarrow laser linewidth.

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Surface-mount sapphire interferometric temperature sensor.

A fiber-optic high-temperature sensor is demonstrated by bonding a 45 degrees -polished single-crystal sapphire fiber on the surface of a sapphire wafer, whose optical thickness is temperature dependent and measured by white-light interferometry. A novel adhesive-free coupling between the silica and sapphire fibers is achieved by fusion splicing, and its performance is characterized. The sensor's interference signal is investigated for its dependence on angular alignment between the fiber and the wafer. A prototype sensor is tested to 1,170 degrees C with a resolution of 0.4 degrees C, demonstrating excellent potential for high-temperature measurement.

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High-speed fiber-optic spectrometer for signal demodulation of inteferometric fiber-optic sensors.

We demonstrated a spectrometer that is capable of acquiring the spectra from interferometric fiber-optic sensors at high speed. The high spectrum acquisition rate is enabled by transforming the spectral information from frequency domain to time domain using a dispersive element and high-speed data acquisition devices. Preliminary results show that the prototype system can record 10,000 frames of spectra per second and achieve a spectrum measurement resolution of 15 nm. Better performance could be realized by using a Raman amplifier and by optimizing the parameters of the system and data processing methods.

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Mode power distribution effect in white-light multimode fiber extrinsic Fabry-Perot interferometric sensor systems.

Theoretical and experimental results have shown that mode power distribution (MPD) variations could significantly vary the phase of spectral fringes from multimode fiber extrinsic Fabry-Perot interferometric (MMF-EFPI) sensor systems, owing to the fact that different modes introduce different extra phase shifts resulting from the coupling of modes reflected at the second surface to the lead-in fiber end. This dependence of fringe pattern on MPD could cause measurement errors in signal demodulation methods of white-light MMF-EFPI sensors that implement the phase information of the fringes.

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All-fused-silica miniature optical fiber tip pressure sensor.

An all-fused-silica pressure sensor fabricated directly onto a fiber tip of 125 microm diameter is described. Simple fabrication steps include only cleaving and fusion splicing. Because no chemical processes are involved, the fabrication is easy, safe, and cost effective. Issues in sensor design and loss analysis are discussed. The sensor has been tested for static pressure response, showing a sensitivity of 2.2 nm/psi, a resolution of 0.01 psi (68.9 Pa), a hysteresis of 0.025%, and capability of operation at temperatures up to 600 deegrees C. This miniature sensor may be suitable for medical diagnostics, environmental monitoring, and other industrial applications.

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Fast-Fourier-transform based numerical integration method for the Rayleigh-Sommerfeld diffraction formula.

The numerical calculation of the Rayleigh-Sommerfeld diffraction integral is investigated. The implementation of a fast-Fourier-transform (FFT) based direct integration (FFT-DI) method is presented, and Simpson's rule is used to improve the calculation accuracy. The sampling interval, the size of the computation window, and their influence on numerical accuracy and on computational complexity are discussed for the FFT-DI and the FFT-based angular spectrum (FFT-AS) methods. The performance of the FFT-DI method is verified by numerical simulation and compared with that of the FFT-AS method.

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Miniature all-silica fiber optic pressure and acoustic sensors.

We present a miniature diaphragm-based Fabry-Perot (F-P) interferometric fiber optic sensor fabricated by novel techniques for pressure or acoustic wave measurement that is only approximately 0.32 mm in diameter. By choosing different diaphragm thicknesses and effective diameters, we obtain a sensor measurement range from 5 to 10,000 psi (1 psi = 51.72 Torr) and a frequency response up to 2 MHz. In addition, the sensor's F-P cavity can be set from micrometers to millimeters with a precision of several nanometers. With the all-silica structure, the sensor is reliable, biocompatible, and immune to electromagnetic interference and has high-temperature sensing capability.

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Simultaneous measurement of refractive index and temperature based on a reflection-mode long-period grating and an intrinsic Fabry-Perot interferometer sensor.

We have demonstrated a single fiber probe for simultaneous measurement of external refractive index and temperature based on two interferometers: a reflection-mode long-period grating (LPG) for refractometry and an intrinsic Fabry-Perot interferometer (IFPI) for temperature measurement. Since the output signal of the combined structure is a superposition of signals produced by both sensors, which have different spatial frequencies, the original signals needed for the index and temperature measurements can be separated and recovered through digital filters.

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In-fiber reflection mode interferometer based on a long-period grating for external refractive-index measurement.

We present two novel schemes for refractometry based on a long-period fiber grating- (LPG-) based Michelson interferometer. These schemes are designed to overcome the measurement dependence of previously demonstrated LPG-based refractometry on the immersion depth. The first utilizes an unshielded LPG and the second, a shielded one. Both schemes were tested over a certain refractive-index range, and the measurement of glucose concentration in water was experimentally demonstrated. In addition, the temperature sensitivity of the two schemes is discussed.

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Frequency-estimation-based signal-processing algorithm for white-light optical fiber Fabry-Perot interferometers.

A novel signal-processing algorithm based on frequency estimation of the spectrogram of single-mode optical fiber Fabry-Perot interferometric sensors under white-light illumination is described. The frequency-estimation approach is based on linear regression of the instantaneous phase of an analytical signal, which can be obtained by preprocessing the original spectrogram with a bandpass filter. This method can be used for a relatively large cavity length without the need for spectrogram normalization to the spectrum of the light source and can be extended directly to a multiplexed sensor system. Experimental results show that the method can yield both absolute measurement with high resolution and a large dynamic range. Performance analysis shows that the method is tolerant of background noise and variations of the source spectrum.

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Measurement of the frequency response of a diaphragm-based pressure sensor by use of a pulsed excimer laser.

We present a novel method for measuring the frequency response of a diaphragm-based optical fiber Fabry-Perot interferometric pressure sensor. The impulse response of the sensor to the radiation pressure generated by an excimer laser pulse is measured. The Fourier transform of the impulse response yields the frequency response of the pressure sensor. Experimental results show that it is a convenient and efficient method for measurement of the frequency response of diaphragm-based pressure sensors.

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Principles and design of multibeam interference devices: a microelectromechanical-systems segment-deformable-mirror-based adaptive spectrum attenuator.

Fourier analysis of multibeam interference shows that the total electric field and relative time delay of the beams form a Fourier-transform pair. Fourier-analysis-based multibeam interference analysis and device design is discussed in detail. The principle of the proposed segment-deformable-mirror-based adaptive spectrum attenuator is illustrated.

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Tunable-optical-filter-based white-light interferometry for sensing.

We describe tunable-optical-filter-based white-light interferometry for sensor interrogation. By introducing a tunable optical filter into a white-light interferometry system, one can interrogate an interferometer with either quadrature demodulation or spectral-domain detection at low cost. To demonstrate the feasibility of effectively demodulating various types of interferometric sensor, experiments have been performed using an extrinsic Fabry-Perot tunable filter to interrogate two extrinsic Fabry-Perot interferometric temperature sensors and a diaphragm-based pressure sensor.

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Miniature fiber-optic multicavity Fabry-Perot interferometric biosensor.

A fiber-optic sensor is designed based on multicavity Fabry-Perot interferometry for the study of optical thickness in self-assembled thin-film layers. This miniature sensor is applicable not only to the measurement of self-assembled polyelectrolyte layers but also to the immobilization of proteins such as immunoglobulin G (IgG). The binding of IgG and the corresponding antigen is observed, and the nonspecific binding characteristics are investigated. The optical thickness changes are used to evaluate the immobilization of the IgG and the immunological activities of the immobilized layers.

Biosensing Techniques↗

Sapphire-fiber-based white-light interferometric sensor for high-temperature measurements.

We present a fiber-optic temperature sensor with a single-crystal sapphire fiber as the light guide and a sapphire wafer as the sensing element. Temperature is determined by measurement of the thermal dependence of the wafer's optical thickness by use of white-light interferometry. We applied digital signal processing techniques to analyze the sensor's spectrum. A prototype sensor was tested to 1600 degrees C and demonstrated excellent reproducibility. An accuracy of +/- 0.2% full scale was obtained. The sensor is simple, small, and flexible, with potential advantages of batch fabrication and easy calibration.

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Fiber-optic extrinsic Fabry-Perot dc magnetic field sensor.

We demonstrate a compact extrinsic Fabry-Perot interferometer-based fiber-optic sensor that uses magnetostrictive amorphous metallic wire Unitika AF-10 (Fe77.5B15Si7.5) as a sensor gauge for measuring dc magnetic fields. We present a theoretical model based on a Gaussian electric field distribution to analyze the sensor operation as a function of longitudinal air-gap separation. The model shows good agreement with the experimental results. A resolution of 50 nT over a range of 50-40,000 nT with a simple passive temperature-compensation method is obtained.

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Exact analysis of low-finesse multimode fiber extrinsic Fabry-Perot interferometers.

A straightforward theory is presented to accurately model the light inferences in a low-finesse multimode fiber extrinsic Fabry-Perot (FP) interferometer. The effect on the fringe visibility of the gap length, sensor structure imperfections, and modal power distributions is explored. The analysis is particularly useful in the design and optimization of sensors that use an extrinsic FP cavity as the sensing element.

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