Images in clinical medicine. Oculo-orogenital syndrome--a deficiency of vitamins B2 and B6.
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Alcoholism↗
Biomedical subjects
André Friedli
Publications and source records attributed to André Friedli.
Unsuccessful treatment of alopecia areata universalis with extracorporeal photopheresis.
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Adult↗
Drug-induced epidermolysis bullosa acquisita with antibodies to type VII collagen.
We describe a 73-year-old patient who had a subepidermal bullous eruption develop after a course of antibiotics, including vancomycin. The patient had deposits of IgA and IgG in the cutaneous basement membrane zone that were located on the dermal side of 1 M NaCl-treated autologous skin. By an enzyme-linked immunosorbent assay, the patient was found to have circulating IgG antibodies directed against type VII collagen, the target antigen of epidermolysis bullosa acquisita. Our observation expands the spectrum of immune-mediated subepidermal bullous skin eruptions precipitated by drugs and lends support to the idea that a subset of these cases represents an unusual variant of drug-triggered epidermolysis bullosa acquisita.
Adenocarcinoma↗
Serpiginous ganglion cyst of the foot mimicking cutaneous larva migrans.
A patient had a serpiginous lesion on the foot that turned out to be a ganglion cyst. This lesion is more common on the hands. On the lower extremity, ganglion cysts tend to have a misleading clinical appearance. Histologic examination shows pseudocysts formed by mucoid degeneration of collagen structures. The pathogenesis is unclear. Many ganglions are asymptomatic, but pain occurs in 50% of cases. Management of symptomatic lesions is surgical excision. Recurrence is possible.
Female↗