Biomedical subjects

Andrea L Stone

Publications and source records attributed to Andrea L Stone.

3 recordsLinked to original sources

PubMed2006

Who is becoming hallucinogen dependent soon after hallucinogen use starts?

This study, based upon epidemiological survey data from the United States (U.S.) National Household Surveys on Drug Abuse (NHSDA) from 2000 to 2001, presents new estimates for the risk of developing a hallucinogen dependence syndrome within 24 months after first use of any hallucinogen (median elapsed time approximately 12 months). Subgroup variations in risk of becoming hallucinogen dependent also are explored. Estimates are derived from the NHSDA representative samples of non-institutionalized U.S. residents ages 12 and older (n=114,241). A total of 2035 respondents had used hallucinogens for the first time within 24 months prior to assessment. An estimated 2-3% of these recent-onset hallucinogen users had become dependent on hallucinogens, according to the NHSDA DSM-IV computerized diagnostic algorithm. Controlling for sociodemographic and other drug use covariates, very early first use of hallucinogens (age 10-11 years) is associated with increased risk of hallucinogen dependence (p<0.01). Excess risk of developing hallucinogen dependence was found in association with recent-onset use of mescaline; excess risk also was found for recent-onset users of ecstasy and of PCP. This study's evidence is consistent with prior evidence on a tangible but quite infrequent dependence syndrome soon after the start of hallucinogen use; it offers leads that can be confirmed or disconfirmed in future investigations.

Adolescent↗

PubMed2005

Adolescent substance use assessment: concordance between tools using self-administered and interview formats.

The present study evaluates the agreement between adolescent self-report of substance use frequencies obtained from a self-administered questionnaire vs. face-to-face interview formats. Participants were 108 adolescents (82 males, 26 females), aged 11 to 19 (M = 15.74, SD = 1.17), who were referred for a chemical dependence assessment between June of 1999 and June of 2000 in Minnesota. The adolescent battery included the self-administered Personal Experience Inventory and the face-to-face interviewer-administered Drug Use History Interview to assess substance use frequency. A urine sample was also collected to validate self-report of recent substance use. Bivariate correlations between adolescent self-report on the self-administered and interviewer-administered formats were strong for alcohol (average r = 0.72) and marijuana (average r = 0.81) use frequencies during the 3 months and 12 months preceding the baseline assessment. However, adolescents were generally more likely to report greater frequencies of alcohol and marijuana use during the interview-administered protocol when compared to the self-administered format. Study implications and limitations are discussed.

Adolescent↗

PubMed2002

Gender differences in psychiatric comorbidity among adolescents with substance use disorders.

The authors examined gender differences in rates of comorbid psychiatric disorders among adolescents with I or more psychoactive substance use disorders. Baseline diagnostic data were obtained from 135 adolescents, ages 12 to 19, and their parents-guardians, who participated in a study to develop and efficacy test Integrated Family and Cognitive-Behavioral Therapy. Rates of attention-deficit/hyperactivity disorder and conduct disorder were higher among drug-abusing male adolescents compared with drug-abusing female adolescents. However, high rates of disruptive behavior disorders also characterized drug-abusing female adolescents. Similarly, drug-abusing female adolescents exhibited a higher rate of major depression compared with drug-abusing male adolescents. However, rates of dysthymia, double depression (i.e., major depression and dysthymia), and bipolar disorder were equivalent between genders.

Adolescent↗