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Biomedical subjects

Andreas Filippi

Publications and source records attributed to Andreas Filippi.

6 recordsLinked to original sources

Extraoral endodontic treatment by retrograde insertion of posts: a long-term study on replanted and transplanted teeth.

OBJECTIVE: The aim of the study was to investigate the healing results of teeth replanted or transplanted in different indications and treated by extraoral root canal therapy. STUDY DESIGN: Extraoral root canal treatment was performed from a retrograde direction with posts made of ceramics or titanium. Preoperatively, the pulp status was classified as definitely infected (n = 47) or not infected/symptomless (n = 78), and the condition of the periodontal ligament (PDL) was classified as damaged (n = 50) or not damaged (n = 75) according to trauma type and extraoral storage. The healing after replantation or transplantation was diagnosed as functional, ankylosis, or infection depending on clinical and radiographic findings. RESULTS: In total, 125 teeth in 99 patients were replanted or transplanted. Mean observation period was 44.4 months. Teeth with a less damaged PDL in no case exhibited ankylosis/replacement resorption after a mean observation period of 53 months. Teeth without preoperative infection of the pulp in no case showed infection-related complications after a mean observation period of 30 months. Teeth classified as definitely infected before treatment had a high frequency of continuous periradicular bone and root resorption. CONCLUSIONS: The extraoral insertion of posts appeared to inflict no additional damage to the PDL that was clinically relevant. Infection-related complications were prevented. Teeth that were classified as definitely infected at the time of treatment had a low rate of healing and should undergo conventional root canal disinfection before this surgical procedure is applied.

Adolescent↗

Treatment of replacement resorption with Emdogain--a prospective clinical study.

The present clinical study investigated the outcome of intentional replantation using Emdogain for periodontal healing following trauma-related ankylosis. Sixteen ankylosed teeth affected by replacement resorption were treated as follows: After tooth extraction, the root canal was obturated with a retrograde titanium post. Emdogain was applied to the root surface and into the extraction socket with subsequent replantation of the tooth. Evaluation parameters included horizontal and vertical Periotest scores, percussion sound and periapical radiographs. All findings were compared to those of the adjacent teeth. The mean follow-up period was 15 months (range 4-24 months). Eleven teeth showed no signs of recurrence of ankylosis: they were in full function and exhibited no pathological clinical findings. Four severely traumatized teeth demonstrated a recurrence of ankylosis after a mean period of 6 months, one tooth was lost in a second accident after 7 months. The estimated probability of 1 year without recurrence of ankylosis was P=0.66 (95% confidence interval [0.40; 0.94]). The mean survival time was 10.2 months (SD 1.1). The results indicate that treatment of replacement resorption following light to moderate trauma with replantation and Emdogain appears to prevent or delay recurrence of ankylosis in many cases.

Adolescent↗

PCNA-expression of cementoblasts and fibroblasts on the root surface after extraoral rinsing for decontamination.

Periodontal cells capable of proliferation were studied immunohistochemically on extracted human teeth after 2-min irrigation with saline or ozonized water and marking of Proliferating Cell Nuclear Antigen (PCNA). All specimens expressed PCNA. The labelling index (LI), i.e. the number of positive cells compared to the total number of cells, was 6.6% after irrigation with saline and 7.8% after irrigation with ozone. There was no difference in number and distribution of PCNA-positive cells from the coronal to the apical thirds of the roots. Irrigation with ozonized water showed higher labelling indices in comparison with saline, but this could not be statistically substantiated (P = 0.24). Ozonized water, not being isotonic, had no negative effect on periodontal cells remaining on the tooth surface after irrigation for 2 min.

Cell Division↗

Comfort and discomfort of dental trauma splints - a comparison of a new device (TTS) with three commonly used splinting techniques.

The present experimental study compared four dental trauma splints in 10 volunteers. The evaluated splints included a wire-composite splint (WCS), a button-bracket splint (BS), a resin splint (RS), and the newly developed titanium trauma splint (TTS). All splints were bonded to the labial surfaces of the maxillary lateral and central incisors and left in place for 1 week. After splint removal, the next splint was placed after a 1-week rest period. The sequence of splint application was randomized for each individual. The following subjective parameters were assessed using a visual analogue scale: sensitiveness of splinted teeth, irritation of the gingival margin, irritation of the lips, impairment of speech, eating and oral hygiene. The results show that the application of BS leads to a significantly higher irritation of the lips and greater impairment of speech compared to other splints (P < 0.05). The RS leads to an increased and significantly higher irritation of the gingiva (P < 0.05) owing to a significant increase in cleaning difficulties (P < 0.05). In conclusion, WCS and TTS appear to be more accepted splints according to a subjective assessment by 10 volunteers.

Acrylic Resins↗

Knowledge and prevention of dental trauma in team handball in Switzerland and Germany.

The aim of this work was to conduct a comparative study between Switzerland and Germany about the frequency of dental injuries in handball, athletes' habits of wearing mouthguard, as well as the general level of information about first emergency measures after a dental trauma and the resulting consequences for athletes and their coaches alike. For this, using interviews, seven handball teams each in two countries (Switzerland/Germany) belonging to the amateur and semiprofessional leagues were surveyed. A total of 112 individuals, 28 females and 84 males, were interviewed. Thirty-two of the 112 interviewees have once observed a dental injury; 12 have experienced a dental injury themselves. Only 10 individuals wore a mouthguard. The results show that the area of handball still requires more information and education.

Adult↗