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Biomedical subjects

Andrew G Cobb

Publications and source records attributed to Andrew G Cobb.

3 recordsLinked to original sources

Bandaging technique after knee replacement.

BACKGROUND: Firm bandaging of the knee following knee replacement may prevent bleeding into the joint by a tamponade effect. We studied the pressure required to achieve tamponade, and then clinically compared the use of a compression bandage with the use of a standard crêpe bandage, with or without a drain. METHOD: Transducers were used to measure the pressure achieved on the surface of the knee under different bandages, and within the knee following release of the tourniquet. We prospectively compared 3 series of 50 patients each: (1) with compression bandaging from toes to mid-thigh, (2) with crêpe bandage from mid-calf to mid-thigh alone, or (3) with crêpe bandage and suction drain. RESULTS: The pressure within the joint at which tamponade occurs is 52-62 mm Hg. The pressure on the skin under a properly applied compression bandage is between 28 and 32 mm Hg, and this controls bleeding within the joint. Patients treated with compression bandaging recovered more quickly from the operation, had a shorter hospital stay, and a greater range of flexion on discharge. They had no swelling of the limb, rarely suffered a tense hemarthrosis, and had fewer complications. INTERPRETATION: The use of a compression bandage incorporating the foot and calf following knee replacement surgery, without the use of drains, confers specific advantages over the use of a crêpe bandage alone.

Aged↗

Poor results after augmenting autograft with xenograft (Surgibone) in hip revision surgery: a report of 27 cases.

BACKGROUND: Surgibone Unilab is prepared from bovine bone and contains hydroxyapatite and protein. It is supposed to be immunogenically inert but the protein could be antigenic in man. PATIENTS AND METHODS: We followed 27 patients for an average of 2.5 (1-5) years, all of whom had received Surgibone mixed with autograft to fill in defects in the acetabulum and the proximal femur in revision hip surgery. RESULTS: In 17 patients, there was apparently complete incorporation of the bone graft within 6 months. In 3 of these patients, the graft was incorporated after 3 months. In 3 patients, however, there was no incorporation of the graft as late as 3 years after the operation. 3 other patients appeared to have a type of graft rejection (pseudoinfection). 1 other patient suffered MRSA deep infection of the prosthesis which resulted in removal of the implants 1 month postoperatively. INTERPRETATION: Use of Surgibone xenograft in revision hip surgery, even in combination with autograft, resulted in failure and the need for rerevision in at least one quarter of the cases studied.

Acetabulum↗

Lateral release for patellofemoral arthritis.

PURPOSE: To determine the outcome of treatment of patients with symptomatic patellofemoral osteoarthritis by closed lateral patellar retinacular release. TYPE OF STUDY: Retrospective study. METHODS: Fifty patients who underwent 53 lateral retinacular release procedures between 1995 and 1999 for the treatment of symptomatic patellofemoral arthritis were assessed by questionnaire comprising the Oxford knee score, a visual analogue scale (VAS, 0-10) for pain, and questions relating to level of patient satisfaction. Patients were included in this study whether or not tibiofemoral arthritis was present, but lateral release was performed only in those for whom the anterior knee pain of patellofemoral arthritis appeared to predominate. RESULTS: The average patient age was 53 years (range, 27 to 79 years). There were 14 men (28%) and 36 women (72%). Follow-up was a mean of 31 months (range, 12 to 65 months). Four patients underwent total knee replacement at 7, 14, 16, and 18 months after lateral release for recurrence of symptoms. In the remaining 49 knees, mean pain VAS was 3.8 +/- 2.8. In 39 knees (80%), patients judged that they had experienced a reduction in pain compared with their preoperative state (2 were pain free), 8 (16%) were unchanged, and 2 (4%) were worse. The average Oxford knee score was 27 (range, 12-48). At follow-up, 33% of patients were very satisfied, 26% satisfied, and 41% dissatisfied with their knee. The presence of tibiofemoral disease did not affect any of the outcome measures. Two patients developed superficial infections of the arthroscopic port sites. There were no cases of hemarthrosis. CONCLUSIONS: Arthroscopic lateral release is effective in reducing the pain of symptomatic patellofemoral osteoarthritis and gives reasonable rates of patient satisfaction irrespective of the presence of tibiofemoral arthritis.

Adult↗