Introduction: HIV/AIDS and Aging.
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Acquired Immunodeficiency Syndrome↗
Biomedical subjects
Andrew Monjan
Publications and source records attributed to Andrew Monjan.
Sleep, health, and aging. Bridging the gap between science and clinical practice.
Problems with sleep are common with advancing years and occur in over half of adults age 65 and older. It has been estimated that insomnia affects about a third of the older population in this country. This inability to have restful sleep at night results in excessive daytime sleepiness, attention and memory problems, depressed mood, falls, and lowered quality of life. Other factors associated with aging, such as disease, changes in environment, or concurrent age-related processes also may contribute to problems of sleep. Data indicate that age by itself does not predict incident complaints of insomnia, even in the presence of lowered sleep efficiency and decreased proportion of slow-wave sleep. Rather, the prevalence of insomnia and other sleep disorders is high in the geriatric population due to the associated comorbidities common in late life. It is now evident that disturbance in sleep can also lead to adverse changes in functioning of a number of body systems.
Accidental Falls↗
Sleep-disordered breathing and cognitive impairment in elderly Japanese-American men.
STUDY OBJECTIVE: To assess the association between sleep-disordered breathing and cognitive functioning in an elderly cohort of Japanese-American men. DESIGN: Cross-sectional study. SETTING: The Honolulu-Asia Aging Study of Sleep Apnea, Oahu, Hawaii. PARTICIPANTS: 718 men between 79 and 97 years of age examined in 1999 and 2000. MEASUREMENTS: Apnea-hypopnea index from in-home overnight polysomnography, performance on the Cognitive Abilities Screening Instrument, body mass index, neck circumference, Epworth Sleepiness Scale, snoring, Center for Epidemiologic Studies Depression 11-item depression scale, physical disability, and history of heart disease, stroke, hypertension, diabetes, and dementia. RESULTS: Less than 30% of the men had no sleep-disordered breathing (apnea-hypopnea index < 5) and nearly one-fifth (19%) had severe sleep-disordered breathing (apnea-hypopnea index > or = 30). Severe sleep-disordered breathing was associated with higher body mass index, habitual snoring, and daytime drowsiness. No association was found between sleep-disordered breathing and cognitive functioning, including measures of memory function, concentration, and attention. CONCLUSIONS: Sleep-disordered breathing was associated with more drowsiness but not with poor performance on standardized cognitive tests used to screen for Alzheimer disease and other dementias in older persons. Because a healthy-participant effect may have contributed to this finding, more extensive cognitive testing may be necessary to reveal more subtle deficits from sleep-disordered breathing.
Aged↗