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Andrzej Zieliński

Publications and source records attributed to Andrzej Zieliński.

At least 19 recordsLinked to original sources

[Epidemiology of tick-borne diseases in Poland].

The paper summarizes state of art knowledge on tick-borne diseases epidemiology in Poland. The most prevalent diseases are Lyme borreliosis (LB) and tick-borne encephalitis (TBE). Although there is growing number of data published on anaplasmosis and babesiosis prevalence in ticks and humans, there is no national data on these diseases and their epidemiological features remain unclear. All tick-borne agents have a common vector tick--the sheep tick Ixodes ricinus. LB and TBE are mandatory reportable diseases. In 2005 case definitions were implemented in Poland to allow a better comparability of data within the country and with other European countries. LB is widespread in Poland. Studies of prevalence of infected ticks indicate that from 6 to 15% of I. ricinus ticks in different sites are infected with the spirochete. Data from seroepidemiologic studies and from routine surveillance (started in 1996) confirm that the disease is widespread in Poland, and its incidence is increasing. It has increased from 2.31 per 100,000 in 1999 to 11.55 in 2005. One reason of this increase is the improvement in diagnosis of the disease. There is a need to promote personal protection during outdoor activities and knowledge on LB symptoms, especially among populations at risk--forestry workers, farmers. TBE incidence is limited to two main foci--one in the Northeast of Poland bordering Baltic states endemic region, and the second on the South of Poland, neighbouring the Czech and Slovak republics. Seroepidemiologic data, supported by surveillance data, indicate that there are areas of particularly high TBEV activity. The mostly affected occupational groups are: unemployed, retired, students, and farmers. This is a reason to promote personal protection and prophylactic vaccination of both inhabitants of endemic regions and tourists visiting endemic regions.

Adolescent↗

[Vaccination against hepatitis B and the risk of multiple sclerosis].

A paper on sclerosis multiplex as sequellae of vaccination against hepatitis B with recombinant vaccine was published in the journal of "Neurology" in September 2004. Problem was evaluated in United Kingdom on the ground of General Practice Research Database (GPRD). In 1996 similar problem was evaluated with negative results in several studies. Just now in opinions of many institutions as well as many persons vaccination against hepatitis B with recombinant vaccine should be continued in similar way as it was performed to this time.

Health Knowledge, Attitudes, Practice↗

[Surgical management of deep chemical burns of the eyelids].

Chemical burns of the eyelids are common, and this may lead to ocular damage. A direct insult of the eyes that result in permanent damage, is rare in facial burns. The majority of the chemical burns of eyelids are partial-thickness that heal spontaneously in 1 week. Whereas, 10 percent are full-thickness burns that require release of contractures and grafts. Wound contracture can cause ectropion of the eyelid, resulting in exposure keratitis, conjunctivitis, corneal ulcers, perforation, and even blindness. At our departments, thirteen patients with 28 chemical burns of eyelids of third-degree, were reviewed. The eyelids had burns wounds with granulation and necrotic tissue. All patients had severe cicatrical ectropion. The eyelids were released with incisions running along the eyelid margin, down to the orbicularis muscle, including the distal part of the levator palpebrae superioris muscle, when necessary. To cover the resulting defects, we use generous full-thickness skin grafts, if available, for both the upper and lower eyelids. Rarely has a tarsorrhaphy been required, and properly constructed dressing provides satisfactory eyelid margin immobilization and conjunctival hygiene. Eighteen full-thickness grafts in 10 patients are reported 8 to 12 weeks after grafting. In seven eyelids, 3 patients developed ectropion and required reconstruction of the eyelids. Our series demonstrates that the early grafting of eyelid burns with full-thickness grafts, can prevent the development of recurrent cicatrical ectropion. Split-thickness grafting should be limited to cases where we can not find the hairless donor site for full-thickness skin grafts.

Adult↗

[Infectious diseases in Poland in 2003].

The most frequent infectious disease as in the previous years was influenza. 1,216,285 cases were reported (3,184.4/100,000). Number of foodborne infections and intoxications remains high--20,221 cases (52.9/100,000). 81.6% of them were caused by Salmonella. In 15.5% of them etiologic factor was not found. In this number Campylobacter infections, rarely tested in Poland may be hidden. Especially alarming is number of cases of diarrhea among children 0-2. Seasonality of childhood diarrhea indicates domination of viral infections, most probably rotaviral among them. There was noted decrease of incidence of newly diagnosed cases of viral hepatitis B (4.7/100,000) which dropped to the level of the incidence of viral hepatitis C (5.9/100,000). Hepatitis A remains at the low level (0.39/100,000). Level of newly diagnosed cases of AIDS (116 cases, 0.36/100,000) remains relatively stable for last few years. The major problem is decreasing reporting of possible risk factors. Infectious diseases caused 0.75% of deaths. Mortality from infectious diseases was 7.2/100,000 and was significantly higher among men (9.5) then among women (5.0). In urban settings mortality from infectious diseases was higher (7.3/100,000) then in the country (6.9). As in previous years, the highest number of deaths was caused by tuberculosis and its late sequels (34.4%). Attention should be given to the increased number of deaths due to sepsis (32.3%, without neonatal sepsis).

Adolescent↗

[Pertussis in Poland in 2003].

Since reemergence of pertussis in Poland since 1997/1998 shift of incidence toward older groups of age was observed. Possible explanations include decreased effectiveness of used whole cell pertussis vaccine and lack of booster vaccinations in the age older than two. At least this last possibility was eliminated by introduction of additional dose of DTaP at the age of 6. Though effects of this change may be observed within several oncoming years. 2034 cases were reported in 2003, a slight increase from the previous year (1788 in 2002) More cases occurred among females (1159 cases, 5.9/100,000) than among males (875 cases, 4.7/100,000) and in urban areas (6.8/100,000) than in the rural ones (2.9/100,000). Big differences in numbers of cases reported between different districts and between urban and rural areas bring strong possibility of insufficient sensitivity of the surveillance in many regions of Poland.

Adolescent↗

[Tetanus in Poland in 2003].

In last decade gradual decrease in numbers of reported cases of tetanus was observed. In 2003, 30 cases of tetanus (14 women and 16 men) were reported in Poland. All those cases were among people of age 20 or more. In 2003 relatively high number of 14 deaths were recorded. All cases were unvaccinated or vaccination status was unknown. The data show effectiveness of vaccination program in younger age groups, but they also show need for promotion of post exposure prophylaxis, especially among older people both in rural and in urban areas. No case of neonatal tetanus was noted in Poland since 1984.

Adolescent↗

[Rationale for vaccinations against chickenpox].

The article presents epidemiological situation of smallpox in them world and in Poland. On the basis of registered numbers of cases, as well as estimated numbers of complications problem of vaccination programs is analyzed. Strategy of general vaccination of children vs. Vaccination of risk groups is discussed.

Adult↗

The effectiveness of vaccination with whole-cell pertussis vaccine by age group in Poland 1996-2001.

Recurrence of pertussis in highly vaccinated populations has been observed in many countries. Two mechanisms have been proposed to explain it: a shift in incidence towards older age groups in which the protective effect of vaccination is diminished; and vaccine-induced changes in genomic and immunological characteristics of circulating strains of Bordetella pertussis, which become different from vaccine strains, thereby reducing vaccine efficacy. Marked increase in the incidence of pertussis has been observed in Poland since 1997, following a decade of stability at a low level. As previously shown, the immunization calendar in Poland does not ensure sufficient protection among children older than 9 y. The decrease in the protective effect becomes noticeable after the age of 5. In this paper we examine changes in the effectiveness of pertussis vaccination in 4 age groups during 1996-2001, using surveillance data. We find that over that period a decrease occurred in the reported effectiveness (in children aged 2 to 5 y, from 97.3% in 1996 to 73.5% in 2001 and in 6 to 9 y-olds, from 84.3%, to 68.8%). We also discuss an alternative hypothesis that the above findings are due to selection or measurement bias resulting from incomplete reporting or imperfect diagnostic procedures.

Adolescent↗

[Infectious diseases in Poland in 2002].

New regulations concerning infectious diseases effective in Poland since 2002 did not changed surveillance of infectious diseases. The most frequent infectious disease as in the previous years was influenza. 228.055 cases were reported (596.5/100,000). Number of foodborne infections and intoxications remains high--26.734 cases (69.0/100,000). 77% of them were caused by Salmonella. In this high number of foodborne infections in 4,492 (16.8%) etiologic factor was not found. In this number Campylobacter infections, rarely tested in Poland may be found. Especially alarming is number of cases of diarrhea among children 0-2. Age adjusted incidence of 2.464/100,000 is the highest occurrence among infectious diseases in Poland. There was noted decrease of incidence of newly diagnosed cases of viral hepatitis B (5.3/100,000) which dropped to the level of the incidence of viral hepatitis C (5.17/100,000). Hepatitis A remains at the low level (0.9/100,000). Level of newly diagnosed cases of AIDS (113 cases, 0.3/100,000) remains relatively stable for last few years. The major problem is decreasing reporting of possible risk factors. Infectious diseases caused 0.74% of deaths. Mortality from infectious diseases was 6.9/100,000 and was significantly higher among men (8.9) then among women. (5.1). In the age groups 35-64 it was 3-4 times higher. In urban settings mortality from infectious diseases was higher (7.2/100,000) then in the country (6.6). In particular districts (voivodeships) mortality indices remained in the range of 4.3 (opolskie) to 11.4 (ślaskie). As in previous years, the highest number of deaths was caused by tuberculosis and its late sequels (35.4%). Attention should be given to the increased number of deaths due to sepsis (33.6%, without neonatal sepsis).

Adolescent↗

[Pertussis in Poland in 2002].

Reemergence of pertussis in a form of epidemic was observed in Poland in 1997/1998. It is rather sustained trend of increased incidence and shift in the age of infected. It may be due to the level of immunity decreasing with age, since according to the vaccination calendar in Poland, last pertussis vaccination is given before the age of two. 1788 cases were reported in 2002, a slight drop from the previous year (2411 in 2001) More cases occurred among females (1043 cases, 5.3/100,000) than among males (745 cases, 4.0/100,000) and in urban areas (5.7/100,000) than in the rural ones (3.0/100,000). Big differences in numbers of cases reported between different districts and between urban and rural areas bring strong possibility of insufficient sensitivity of the surveillance in many regions of Poland. It is concluded that increase of pertussis incidence in Poland, brings urgent need of additional vaccination in the age of 6 to secure protection for the older age groups. Additional dose of pertussis vaccine was included in vaccination calendar for 2003.

Adolescent↗

[Meningitis and encephalitis in Poland in 2002].

In Poland, 861 cases of bacterial meningitis and encephalitis, 307 cases of viral encephalitis, 1022 of viral meningitis and 286 cases of meningitis and encephalitis of other or unknown etiology were reported in 2002. Incidence of the bacterial central nervous system infections has been declining over the past decade and the level of viral infections, following the outbreak in the mid-nineties, remained stable. Etiological factor was determined in 365 (42%) cases of bacterial meningitis/encephalitis. Among them Neisseria meningitidis was found in 90 cases, Haemophilus influenzae in 72 cases and Streptococcus pneumoniae in 85 cases. As in the past type B was the predominant type of N. meningitidis cultured from the patients, but type C appears to be on the rise accounting for 35% of the serotyped strains. 126 cases of tick borne encephalitis were reported in Poland in 2002, most of them from endemic areas of north-eastern part of the country.

Adolescent↗

[Tetanus in Poland in 2002].

In last decade gradual decrease in numbers of reported cases of tetanus was observed. In 2002, 20 cases of tetanus (12 women and 8 men) were reported in Poland. All those cases were among people of age 30 or more. Only one man more then 79 years old died. All cases were unvaccinated or vaccination status was unknown. The data show effectiveness of vaccination program in younger age groups, but they also show need for promotion of post exposure prophylaxis, especially among older people both in rural and in urban areas. No case of neonatal tetanus was noted in Poland since 1984.

Adolescent↗

[Malaria in Poland in 2002].

26 cases of malaria were reported in Poland in 2002. All cases were imported: 20 from Africa and 6 from Asia. Most of the cases (15) were caused by Plasmodium falciparum. 17 cases were men, 9 were women. Mean age was 40. The youngest patient was 11, the oldest 71. Table I presents complete [table see: text] list of cases by gender (M-male, K-female), age, etiologic factor and presumed country of infection. In only 4 cases some kind of chemoprophylaxis was documented. In other prophylaxis was not used or not documented. One death resulted from falciparum malaria in Poland in 2002.

Adolescent↗

[Smallpox--historical or real threat].

Presently, there is no real possibility of natural re-emergence of smallpox virus, which was eradicated globally more then 25 years ago. During the last decade the possibility of use of smallpox virus as a biological weapon by a criminal organisation was emphasised. The re-emergence of smallpox virus would lead to unprecedented disaster. Theoretical models indicated that only extremely strict and enforced interventions could stop the spread of epidemic, but the assumptions of these models were unrealistic. Presently, there are limited stocks of the first generation smallpox vaccine left in the world. This vaccine, as well as the second-generation vaccine are associated with multiple adverse events, including fatalities and may not be accepted by society. Much safer vaccines are now being developed. Strategic plan of prophylactic vaccinations requires defining the groups to be immunised in the first place and whether immunisation should start before or after a first smallpox case would occur.

Bioterrorism↗

[Infectious diseases in Poland in 2001].

In 2001 surveillance system of infectious diseases in Poland remained unchanged. New cases of infectious diseases were recorded in 103 positions including intoxications. Tuberculosis and sexually transmitted infections were registered in separate systems. Influenza was the most frequently reported infectious disease with 576,449 cases, 63.9% less then in the previous year. The next most numerous were foodborne infections, which were reported in 24,393 cases, including 19,788 cases of infections caused by Salmonella sp. An increase in incidence was observed in the following diseases: viral hepatitis type A, rubella, measles and pertussis. Also the number of recorded cases of Lyme boreliosis and tickborne encephalitis were higher then in 2000. Incidence of AIDS remained within the range recorded during the last few years. In 2001 further drop in incidence of viral hepatitis type B was observed reaching the level of 6.2 per 100,000. It was the result of implemented comprehensive program of prophylactic measures, which brought incidence of this disease from the highest in Europe down to the level close to European average. Infectious diseases contributed to 0.75% of deaths. The most frequent cause of death among infectious diseases was tuberculosis and its sequels (1,061 cases). 13 cases of death due to tuberculosis occurred in people below 30 years of age.

Adolescent↗

[Pertussis in Poland in 2001].

In 2001 global increase in reported cases of pertussis in Poland was observed. The total number of reported cases was 2411, 142 more than in 2000. A general trend of increase in the fraction of older cases continues since 1992. More cases occurred among females (7.0/100,000) than among males (5.4/100,000) and in urban areas (7.8/100,000) than in rural areas (3.7/100,000). The vaccination coverage for the children below 2 was 98.2%. The quality of the reporting and laboratory confirmation of pertussis has improved. 58.6% of cases were confirmed by ELISA test, 0.1% by culture.

Adolescent↗

[Meningitis and encephalitis in Poland in 2001].

2367 cases of meningitis and 571 of encephalitis were reported in Poland in 2001. Among meningitis 1324 cases were classified as viral and 838 as bacterial. Among encephalitis cases, 117 were classified as bacterial and 383 as viral. Etiological factor was determined in 419 (44%) cases of bacterial meningitis/encephalitis. Among them Neisseria meningitidis was found in 106 cases, Haemophilus influenzae in 75 cases and Streptococcus pneumoniae in 99 cases. As in the past type B was the predominant type of N. meningitidis cultured from patients. 210 cases of tick borne encephalitis were reported in Poland in 2001, most of them from endemic areas of north-eastern part of the country.

Adolescent↗

[Tetanus in 2001].

In 2001, 21 cases of tetanus were registered in Poland. The incidence rate of tetanus was 0.04/100,000 population. No neonatal tetanus cases were recorded. All cases except one occurred among peple of age 50 or more. Case fatality rate associated with tetanus was 33.3% and increased with age. All cases were unvaccinated or vaccination status was unknown. The data show effectiveness of vaccination program, but also show need for promotion of post exposure prophylaxis, especially among older people.

Adolescent↗