[When to discharge a patient after acute coronary syndrome?].
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Angina, Unstable↗
Biomedical subjects
Anna Konopka
Publications and source records attributed to Anna Konopka.
Factors affecting the potentiometric response of all-solid-state solvent polymeric membrane calcium-selective electrode for low-level measurements.
An all-solid-state calcium-selective electrode was constructed with poly(pyrrole) solid-contact doped with calcium complexing ligand Tiron. The potentiometric response of this sensor can have a linear range down to 10(-)(9) M with a slope close to Nernstian and detection limit equal to 10(-)(9.6). The effects of pH and the activity of the interfering ion in the conditioning solution on the potentiometric behavior of the constructed sensors were examined. Potential stability, reproducibility, and impedance studies were performed. The selectivity of the constructed electrode is better than that of the conventional calcium-selective electrode with internal filling solution of 10(-)(2) M CaCl(2) and comparable to that of the best liquid-contact electrodes.
Calcium↗
[Plethysmographic assessment of pulse wave may be helpful in the detection of prosthetic valve dysfunction--a case report].
A case of a 63-year-old female with prosthetic mitral and aortic valves is described. The long-term post-operative period was complicated by infective endocarditis, persistent atrial fibrillation requiring pacemaker implantation and total a-v node ablation as well as ischaemic stroke which occurred one year before present hospitalisation. This time the patient was admitted to the hospital due to progressive heart failure. Transesophageal echocardiography showed a cyclic intermittent opening of both prosthetic valves full opening was present during every second cardiac cycle. The same phenomenon was documented using plethysmographic recording of a pulse wave from a finger. The patient underwent prosthetic valve replacement. Intraoperatively, a fibrous tissue ingrowth was detected.
Aortic Valve↗
Is the assessment of lipid profile performed up to seventy two hours from hospital admission due to acute coronary syndrome still valid?
BACKGROUND: Serum concentration of lipids and lipoproteins changes during the course of acute coronary syndrome (ACS). Total cholesterol and LDL-cholesterol levels decrease. Also HDL-cholesterol and triglyceride levels are not stable. Therefore, it has been suggested that reliable assessment of lipid profile can be performed either during the first 24 hours or after 6 weeks or even 3 months from the onset of ACS. AIM: To examine whether lipid parameters remain stable during the first 72 hours of hospitalisation due to ACS. METHODS: The study group consisted of 84 patients, aged 30-88 years, hospitalised due to ACS, of whom 90% underwent primary percutaneous coronary intervention (PCI). In all patients lipid profile was assessed twice. The first measurement was performed as soon as possible, within 24 hours from hospital admission. The second measurement was obtained within 24 hours from the first sample (group I, n=42), between 24 and 48 hours (group II, n=28), or between 48 and 72 hours (group III, n=15) from the first measurement. Lipid parameters obtained from the first measurement were compared with those obtained during the second assessment. RESULTS: There were no significant differences between lipid parameters measured during the first and second measurement within all three investigated groups nor were there any significant inter-group differences. CONCLUSIONS: Lipid profile assessed within 72 hours from the hospital admission due to ACS is as valid as the measurement performed within the first 24 hours.
Acute Disease↗
All-solid-state calcium solvent polymeric membrane electrode for low-level concentration measurements.
An all-solid-state calcium-selective electrode with a plastic membrane phase containing a calcium ionophore ETH-1001 placed on poly(3-methylthiophene) ion-to-electron transducting layer functionalized to bind calcium cations has been constructed. The obtained potentiometric sensors were characterized with a calibration line of slope close to Nernstian within the activity from 10(-5) to 0.1 M. For Ca2+ activity lower than 10(-5) M, super-Nernstian behavior was observed. The super-Nernstian response that is observed for electrodes with an internal solution strongly binding primary ions was in this case attributed to incorporation of calcium ions in the modified solid-contact phase. With this arrangement, the evaluation of selectivity coefficients much closer to those that depend on the properties of the ion-selective membrane itself was possible.
Journal Article↗
Acute myocardial infarction complicated by cardiogenic shock. In-hospital and mid-term results of invasive treatment in the National Institute of Cardiology, Warsaw-Anin.
BACKGROUND: Mortality in acute myocardial infarction (MI) complicated by cardiogenic shock approaches 90%, regardless of the type of pharmacological treatment. AIM: To assess in-hospital and mid-term results of invasive treatment of patients with acute MI with ST segment elevation (STEMI) complicated by cardiogenic shock. METHODS: From a prospective registry of all patients admitted to our institution for urgent coronary angiography due to acute coronary syndrome between February 2001 and June 2002, patients with STEMI, symptom duration up to 12 hours and cardiogenic shock diagnosed on admission were identified. The in-hospital and mid-term outcome of 37 patients (mean age 65 years, range 54-77, 68% of males) treated with primary percutaneous coronary intervention (PCI) was analysed. RESULTS: Of the 41 patients with STEMI and cardiogenic shock, total occlusion or critical stenosis of a coronary artery were found in 38 patients. One patient with the occlusion of three main coronary arteries underwent urgent surgical revascularisation and remains alive after an 18-month follow-up. In the remaining 37 patients primary PCI of an infarct-related artery was performed (stent implantation in 70%, abciximab administration in 54%) which restored normal blood flow (TIMI grade 3 flow) in 54% of subjects. In patients with TIMI grade 3 flow the in-hospital mortality was 25%. Of the whole PCI-treated group, 18 (48.6%) patients died during stay in our institution, an additional two - after transfer to another hospital, and one - during a 19-month follow-up period. The remaining 16 patients remain alive (median follow-up of 8 months). CONCLUSIONS: Invasive treatment of patients with STEMI complicated by cardiogenic shock significantly reduces mortality in this high-risk population. The mid-term results in patients discharged from hospital are good. Invasive treatment of acute MI should be accessible for all patients with extensive acute MI.
Age Distribution↗
Activated recombinant factor VII (rFVIIa) in bleeding management after therapy with IIb/IIIa-inhibitor tirofiban.
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Anticoagulants↗
[Benign tumour of aortic valve in a patient with tight aortic stenosis - a case report].
A case of 58-year-old male with aortic stenosis who was admitted due to chest pain suggesting acute myocardial infarction, is presented. Transthoracic and transesophageal echocardiography revealed the presence of aortic valve tumour and the patient underwent successful surgery. Symptomatology and treatment of cardiac tumours are discussed.
English Abstract↗