[Treatment of irritable bowel syndrome].
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Biomedical subjects
Publications and source records attributed to Anna Mária Németh.
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In cases of patients of high operation risk the endoscopic stent implantation has the smallest morbidity and mortality as well as it ensures acceptable life quality in non-resec table neoplastic stenosis of liver portal region. In better life expectancy the more expensive metallic stents can be recommended because they are committed with less complications.
Carcinoids are characteristically indolent, but heterogeneous tumors with respect to their site of origin, endocrine features, clinical manifestations and biologic behaviour. The authors summarize the current laboratory, endoscopic and radiologic methods used for the diagnosis of carcinoid tumors. Treatment modalities should be directed against the tumor and the hormonal excess state. The authors review the outcome of most frequently used therapies, including somatostatin-analogue and interferon treatment, chemotherapy, embolization, receptor-targeted radiotherapy and surgical intervention). Patients with carcinoid tumors, with or without carcinoid syndrome, are best managed by a multidisciplinary approach.
Somatostatin and its synthetic analogues have important physiological roles in human. These compounds antagonize the endocrine and exocrine secretion of pancreas, which provide theoretical ground for their use in patients with pancreatic diseases. For a quarter of a century many researchers have investigated the effect of somatostatin and octreotide in animal models of experimental pancreatitis and in patients with acute pancreatitis, and in those with complications of pancreatic operations, fistulas and pseudocysts. In most of these studies the use of synthetic octreotide with longer duration proved to be more efficient. In experimental and acute pancreatitis somatostatin and octreotide were less effective than expected, however, they proved to be helpful in preventing complications of pancreatic operations and in the therapy of fistulas and pseudocysts.