Biomedical subjects

Anna-Ulrika Sarikkola

Publications and source records attributed to Anna-Ulrika Sarikkola.

4 recordsLinked to original sources

PubMed2005

Traumatic cataract and other adverse events with the implantable contact lens.

PURPOSE: To evaluate the surgical outcome and adverse events associated with implantation of the implantable contact lens (ICL) for the correction of high myopia or high hyperopia. SETTING: Helsinki University Eye Hospital, Helsinki, Finland. METHODS: In this nonrandomized prospective clinical trial, the ICL V4 was implanted in 26 eyes of 13 patients with normal enrollment criteria (younger than 45 years, a clinically clear crystalline lens) (Group 1) and the V2, V3, or V4 were implanted in 38 eyes of 22 patients with heterogeneous criteria (older than 45 years or opacities in the crystalline lens) (Group 2). The main outcome measures were lens opacity classification system (LOCS II) assessment and transparency analysis of the lens. RESULTS: In Group 1, microdensitometric assessment showed no decrease in crystalline lens transparency and no statistically significant increase in crystalline lens density at any follow-up examination (P>.05). The incidence of anterior subcapsular (AS) opacities was 7.7%, and no eye developed clinically significant cataract during the mean follow-up of 13.2 months +/- 12.3 (SD). No myopic eye lost a line of best corrected visual acuity (BCVA); 50.0% of hyperopic eyes lost 1 line of BCVA. Sixty-eight percent of myopic eyes and 75.0% of hyperopic eyes were within +/-1.0 diopter of the predicted refraction. In Group 2, the incidence of AS opacities was 47.4% and 10 eyes (26.3%) developed clinically significant cataract during the mean follow-up of 30.9 +/- 18.0 months. The visual and refractive results were similar to those in Group 1 at 1 month, but due to progressive AS opacities in the crystalline lens, 23.4% of eyes lost BCVA lines during the follow-up. Intraoperative complications were few and insignificant. CONCLUSIONS: Implantation of the ICL for correction of high myopia or high hyperopia appears to be a safe procedure with good visual and refractive results immediately. There was no decrease in the transparency or increase in the density of the crystalline lens with the latest generation of the ICL device in the normal group, indicating enhanced safety. Progressive lens opacification in the heterogeneous group shows there are risk factors for cataract formation; ie, type V3 ICL, preexisting lens opacities, and older patient age. Anterior subcapsular opacities are most likely the result of trauma.

Adult↗

PubMed2005

[Adult cataract].

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Age Distribution↗

PubMed2004

Simultaneous bilateral cataract surgery: a retrospective survey.

PURPOSE: To evaluate patient satisfaction and functional visual outcome, safety, and visual and refractive outcomes of simultaneous bilateral cataract surgery (SBCS). SETTING: North Karelia Central Hospital, Joensuu, Finland. METHODS: A retrospective external review of 200 patients drawn randomly from 637 patients who underwent SBCS at the North Karelia Central Hospital in 2001 was performed. Of the 200 eligible patients, 141 who returned a completed questionnaire on patient satisfaction and functional visual outcome of SBCS were enrolled. Postoperative refraction and best corrected visual acuity (BCVA) were available in 148 eyes of 74 patients. RESULTS: The surgery was carried out under topical anesthesia, and 98% were outpatient surgeries. No serious intraoperative or postoperative complications occurred. Of the 141 patients, 96% (95% confidence interval [CI]: 91-98) experienced SBCS as positive or quite positive, 89% (95% CI: 83-94) felt safe to go home after the surgery, and 91% (95% CI: 85-95) would recommend SBCS to their relatives or friends. The mean visual functioning index (VF-7 score) was 87.3 (median 95). Postoperative BCVA was 20/40 or better in 84% (95% CI: 77-89) and 20/25 or better in 66% (95% CI: 57-73) of the 148 eyes examined. The postoperative refraction was +/-0.75 diopter (D) of the target value in 78% (95% CI: 71-85) and +/-1.5 D in 95% (95% CI: 91-98), and the mean anisometropia was 0.26 D (SD 0.6 D, range 0-1.65). CONCLUSION: This study provides evidence that SBCS by experienced surgeons is likely to be a safe and efficient procedure and is positively received by patients.

Adult↗

PubMed2004

Quality of vision after AMO Array multifocal intraocular lens implantation.

PURPOSE: To evaluate safety and efficacy of Array SA40N multifocal intraocular lens (IOL) (AMO) implantation in cataract surgery. SETTING: Helsinki University Eye Hospital, Helsinki, Finland. METHODS: In this prospective randomized comparative trial, 80 patients scheduled for cataract surgery were selected based on preoperative counseling and randomized to have multifocal or monofocal IOL implantation. Fifty-three eyes of 35 patients received a multifocal IOL and 67 eyes of 40 patients, a monofocal IOL. The incidence of complications and visual outcome in the multifocal and monofocal IOL groups were compared. Quality of vision was measured by comparing the severity of visual symptoms (glare, halos, and cataract symptoms score), changes in functional impairment measured by a 7-item visual function test (VF-7), changes in global measures of vision (trouble and satisfaction with vision), and range of accommodation and contrast sensitivity. RESULTS: Intraoperative and postoperative complications and adverse events were few and required no further surgical intervention. Both distance and near visual acuities were significantly better in the multifocal group than in the monofocal group; the difference was most prominent in distance corrected near acuity (P<.001). Thirty-five eyes (67.3%) in the multifocal group and 10 eyes (14.9%) in the monofocal group achieved a distance corrected near acuity of J6 (20/40) or better; 30 eyes (56.6%) and 19 eyes (28.4%), respectively, achieved a best corrected distance acuity of 20/20 or better. Glare symptoms decreased postoperatively in both groups but were slightly more common in the multifocal group. In contrast, halos were significantly more common at 1 month in the multifocal group (P<.001). Contrast sensitivity values were slightly lower with multifocal IOLs at almost all spatial frequencies, but the difference was not significant. The change in the quality of life postoperatively, measured with the VF-7, was significant and identical in both groups. CONCLUSIONS: Pseudophakic eyes with multifocal IOLs had better distance and near acuity and range of accommodation than eyes with a monofocal IOL. Slightly lower contrast sensitivity and increased perception of halos by subjects with the multifocal IOL appear to be an acceptable compromise to enhanced near and distance vision.

Accommodation, Ocular↗