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Biomedical subjects

Anne Mellon Mogensen

Publications and source records attributed to Anne Mellon Mogensen.

4 recordsLinked to original sources
PubMed2006

[Primary eosinophilic esophagitis].

Primary eosinophilic esophagitis (EE) is a rare disease with symptoms similar to those of gastroesophageal reflux disease (GERD). However, EE is caused by severe eosinophilic invasion of the esophageal epithelium, typically followed by dysphagia. A man 28 years of age presented persistent symptoms of GERD despite traditional antireflux therapy. Histologic evaluation showed eosinophilia (85 eosinophils/high-power field (x 400)). Treatment by bouginage resulted in mucosal lacerations and transitory clinical improvement. Local steroid therapy for four weeks eliminated the symptoms.

Adult↗
PubMed2004

Idiopathic extensive peliosis hepatis treated with liver transplantation.

A 50-year-old Danish man, who neither had wasting disease nor was taking steroid-containing drugs, complained of abdominal distension, due to a markedly enlarged liver. Percutaneous needle biopsies were taken from the liver, and the findings gave suspicion of a neoplastic tumor. Because of reduced liver function and treatment-resistant ascites, he underwent liver transplantation without a definite preoperative diagnosis. The resected liver weighed 2900 g, and almost all of the parenchyma was destroyed and replaced by multicystic blood-filled spaces, diagnosed as extensive peliosis hepatis complicating liver cirrhosis. Extensive peliosis with liver cirrhosis is a rare condition. Only two cases, caused by contraceptives and treated by liver transplantation, are reported in the English-language literature. We could find no cause other than alcohol abuse lasting several years in this patient, and classified the present case as idiopathic extensive peliosis hepatis. Although scarce subjective findings and misleading liver biopsies made an exact diagnosis difficult, an orthotopic liver transplantation was the only treatment for such complicated peliosis hepatis.

Humans↗
PubMedDate not supplied

Endoscopic ultrasonography-guided fine needle aspiration biopsy for staging malignant melanoma of the esophagus. A case report.

BACKGROUND: Malignant melanoma (MM) rarely involves the esophagus. The outlook is dismal unless lesional tissue is limited to the esophageal wall. Hence, staging prior to extensive surgical intervention is desirable. CASE: A 54-year-old male presented with fatigue and melena. A diagnosis of MM primary in the esophagus was rendered on a biopsy of an esophageal polyp. The stage, determined by endoscopic ultrasonography-guided fine needle aspiration biopsy, was advanced. On the basis of this information, it was decided to spare the patient mutilating surgery. CONCLUSION: This report confirms the utility of endoscopic ultrasonography-guided fine needle aspiration biopsy in documenting the extent of lesions at sites difficult to access. Thus, management can be improved.

Biopsy, Needle↗