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Biomedical subjects

Anthony V Benedetto

Publications and source records attributed to Anthony V Benedetto.

18 recordsLinked to original sources

Measurement of the anatomic position of the corrugator supercilii.

OBJECTIVE: To standardize the location of the corrugator supercilii by using known facial landmarks. METHODS: The corrugator supercilii points of origin, insertion, and maximal muscle thickness were measured relative to the nasion and supraorbital notch in 21 cadavers. Comparisons of measurements between male and female cadavers were performed using a two-tailed t-test. RESULTS: The location of the corrugator supercilii was variable but was not significantly different between males and females. From the nasion, the mean point of origin was 4 mm lateral and 6 mm superior, the mean point of insertion was 33 mm lateral and 16 mm superior, and the mean maximal muscle thickness was 16 mm lateral and 10 mm superior. At their point of greatest thickness, most corrugators were found to lie below the upper border of the superciliary arch. CONCLUSIONS: There is variability in the location of the corrugator supercilii that is not gender dependent. When injecting botulinum toxin into the corrugator supercilii, it might be advantageous if the lower forehead skin of the brow is elevated, thus allowing for more precise injection. This may achieve weakness of the targeted muscle with lower doses of botulinum toxin, thus lessening the risk of eyelid and brow ptosis.

Cadaver↗

Botulinum toxin - an update on its use in facial rejuvenation.

The role of botulinum toxin in facial rejuvenation has been greatly expanded in the last several years. In this article, we first review the traditional approach to botulinum toxin therapy in the forehead and glabella. For the advanced reader, we then discuss both the literature and our personal approaches to treatments of the periocular region, mid face, lower face, and neck. Throughout the discussion, attempts are made to include a description of relevant anatomy, the physiologic result of specific muscle activity and denervation, and perhaps most importantly, precise directions for patient treatment.

Journal Article↗

Pilonidal sinus disease treated by depilation using an 800 nm diode laser and review of the literature.

BACKGROUND: Pilonidal sinus disease is a debilitating, disfiguring chronic ailment that is often resistant to therapy. Its etiology and treatment remain in question. OBJECTIVE: To assess the efficacy of an 800 nm diode laser in the treatment of recalcitrant pilonidal sinus disease. METHODS: Two patients with recalcitrant pilonidal sinus disease were treated in the lower back, buttocks, and perigluteal cleft area with an 800 nm diode laser with a spot size of 9 x 9 mm, fluences of 30 to 48 J/cm2, and pulse widths of 15 to 24 milliseconds. RESULTS: Long-term relief of pilonidal sinus disease was produced with as few as two treatments 2 months apart to as many as six treatments over a 2-year period. With each successive treatment, fewer pulses were needed and the interval between treatments increased. CONCLUSION: The 800 nm diode laser may be an effective tool in the treatment of pilonidal sinus disease. By eliminating the source of hair and hair fragments that course along the surface of the lower back and buttocks, interruption of the etiologic source for pilonidal sinus disease can be accomplished.

Buttocks↗

Angiolymphoid hyperplasia successfully treated with an ultralong pulsed dye laser.

BACKGROUND: Angiolymphoid hyperplasia with eosinophilia (ALHE) is a benign vascular proliferation characterized by dermal or subcutaneous nodules or both, primarily in the head and neck. We report the successful treatment of ALHE without scarring using a 595 nm ultralong pulsed dye laser, which applies a unique combination of longer wavelengths, a longer pulse duration, and a higher fluence. OBJECTIVE: To report the use of the 595 nm pulsed dye laser in the treatment of ALHE and to detail the particular aspects of this laser that make it uniquely qualified to treat this entity. METHODS: Case report and review of the literature. RESULTS AND CONCLUSION: This laser may be used as an effective treatment for ALHE and has advantages over alternative treatments and older lasers. Specifically, the longer wavelength (595 nm) penetrates more deeply into dermal tissue, which produces more uniform coagulation across the entire vessel.

Aged↗

Injecting 1000 centistoke liquid silicone with ease and precision.

BACKGROUND: Since the Food and Drug Administration approved the use of the 1000 centistoke liquid silicone, Silikon 1000, for intraocular injection, the off-label use of this injectable silicone oil as a permanent soft-tissue filler for facial rejuvenation has increased in the United States. Injecting liquid silicone by the microdroplet technique is the most important preventive measure that one can use to avoid the adverse sequelae of silicone migration and granuloma formation, especially when injecting silicone to improve small facial defects resulting from acne scars, surgical procedures, or photoaging. OBJECTIVE: To introduce an easy method for injecting a viscous silicone oil by the microdroplet technique, using an inexpensive syringe and needle that currently is available from distributors of medical supplies in the United States. METHOD: We suggest the use of a Becton Dickinson 3/10 cc insulin U-100 syringe to inject Silikon 1000. This syringe contains up to 0.3 mL of fluid, and its barrel is clearly marked with an easy-to-read scale of large cross-hatches. Each cross-hatch marking represents either a unit value of 0.01 mL or a half-unit value of 0.005 mL of fluid, which is the approximate volume preferred when injecting liquid silicone into facial defects. Because not enough negative pressure can be generated in this needle and syringe to draw up the viscous silicone oil, we describe a convenient and easy method for filling this 3/10 cc diabetic syringe with Silikon 1000. RESULTS: We have found that by using the Becton Dickinson 3/10 cc insulin U-100 syringe, our technique of injecting minute amounts of Silikon 1000 is facilitated because each widely spaced cross-hatch on the side of the syringe barrel is easy to read and measures exact amounts of the silicone oil. These lines of the scale on the syringe barrel are so large and clearly marked that it is virtually impossible to overinject the most minute amount of silicone. CONCLUSION: Sequential microdroplets of 0.01 cc or less of Silikon 1000 can be measured and injected with the greatest ease and precision so that inadvertent overdosing and complications can be avoided.

Dimethylpolysiloxanes↗

The use of the spanning suspension suture in facial reconstruction.

BACKGROUND: The closure of large cutaneous defects of the upper face can be challenging, often requiring the use of large rotation, advancement, or transposition flaps or skin grafts. OBJECTIVE: To describe the use of the spanning suspension suture, a technique we have adapted to facilitate closure of large cutaneous defects of the upper face. METHODS: Report of an illustrated case. RESULTS: A large full-thickness defect of the temple was successfully reconstructed using the spanning suspension suture. CONCLUSION: Use of the spanning suspension suture permits recruitment of skin from the lower cheek and neck in the closure of large wounds of the upper face, avoiding the need for transposition or rotation flaps and grafts.

Aged↗

Basal cell carcinoma presenting as a large pore.

BACKGROUND: Certain facial lesions clinically appear as large pores, and when examined microscopically, they are found to be basal cell carcinomas (BCCs). OBJECTIVES: The purposes of this study were to determine the clinical and histologic characteristics of certain large-pore facial lesions, which, on microscopic examination, are found to be BCCs and to identify, if any, a clinical profile of the patients who might be prone to development of such large-pore BCCs. METHODS: Microscopic examination of biopsy tissue, obtained from patients who presented clinically with characteristic large-pore lesions of the face during the years 1988 to 2000, was performed. RESULTS: Eleven biopsy specimens from 10 patients who presented with long-standing, gaping pores in the center of the face were shown to be BCCs with features of follicular differentiation and focal keratinization. These patients also had thick, sebaceous skin, and most were users of tobacco. CONCLUSION: Enlarged pores or pits in the center of the face, present for a long period in patients with thick sebaceous skin, should be examined for evidence of BCC. These large-pore lesions may be BCCs with histologic features of follicular differentiation.

Adult↗

Commentary: botulinum toxin in clinical medicine.

The recent introduction of botulinum toxin (BTX) into clinical medicine has revolutionized the practice of medicine and surgery forever. Who would have ever thought that the world's most deadly of all toxins would be used for therapeutic purposes? The discovery of the beneficial effects of BTX has transformed the lives of many unfortunate individuals who have suffered from a variety of unrelated disorders, which have been virtually impossible to treat. With the help of BTX, these and hopefully many other ailments will be easily managed with a few simple injections.

Botulinum Toxins↗

Cosmetic aspects of pregnancy.

There are a vast number of changes to the female body that occur during pregnancy, to which any pregnant woman will attest. The changes, although considered, for the most part, physiological and not pathological, are quite distressing to many women. This chapter serves to review those changes and comment on their physiological origins. Most of these changes can be definitively or inferentially linked to the dramatic hormonal changes that take place to support a pregnancy. Comments are also made about treatment as they pertain to pregnant women. In addition, a brief discussion about performing cosmetic procedures during pregnancy is included.

Acne Vulgaris↗