Biomedical subjects
Antonio Maffuz-Aziz
Publications and source records attributed to Antonio Maffuz-Aziz.
[Parathyroid glands radio-guided surgery].
INTRODUCTION: Several advances have been made in the management of hyperparathyroidism. The preoperative sestamibi scan appears to have revolutionized the entire approach to parathyroid surgery including minimally invasive parathyroidectomy. Gamma probe is a useful tool that complements a well performed localization of parathyroid adenomas. METHODS: We conducted a retrospective analysis of the patients submitted to radio-guided parathyroidectomy between January and December 2003 at a Oncology tertiary hospital in Mexico City, for evaluate the results and shows the feasibility of this approach. RESULTS: Six patients was included, all of them referred to the hospital with the diagnosis of bone tumors or with bone disease suggest malignancy. Median serum level of preoperative calcium was 13.18 mg/dl. In all cases the transoperative localization of the affected gland was possible using gamma probe and according with Tc 99m sestamibi scintigraphy imaging. None perioperative deaths reported and there were no recurrent laryngeal nerve injuries neither recurrent hypercalcemia. Median serum level of postoperative calcium was 9.39 mg/dl. There were at histopathological analysis five adenomas and one hyperplasia. CONCLUSIONS: Radio-guided parathyroidectomy is a useful approach for transopertaive localization of the affected gland, we obtained a 100% success rate, according with the histopathologic analysis and the normal postoperative serum calcium level.
[Laparoscopic hysterectomy in the surgical treatment of gynecological malignant and premalignant diseases].
INTRODUCTION: Laparoscopic hysterectomy (LH) is a safe surgical approach that offers patients a faster recovery. However, its use in malignant or premalignant gynecological lesions is not well established. The objective of the present study was to show the feasibility of LH in a tertiary cancer center. MATERIAL AND METHODS: We conducted a descriptive analysis of patients with histologically proven malignant or premalignant uterine lesions who underwent to LH. Surgical time, bleeding complications, and hospital stay were evaluated. RESULTS: Twenty-five patients were included with a mean age of 45 years. Ten LH (40%) with or without salpingo-oophorectomy for premalignant or preinvasive malignant lesions were done, five surgical staging procedures for endometrial cancer (20%) and seven radical hysterectomies for cervical cancer (28%). In three patients, conversion from laparotomy (12%) was necessary for operative complications (two cases) or technical problems (one case). Mean operative time for the entire group was 207 min, mean bleeding 204 mL and mean hospital stay was 2.5 days. Postoperative complications were present in two patients, hematoma in the vaginal cupola (one case) and temporary bladder dysfunction (one case). CONCLUSIONS: In the present trial we described our initial experience in LH for the treatment of malignant and premalignant gynecologic diseases. Our results suggest that it is a safe and feasible surgical approach. Long-term surveillance studies are necessary for the evaluation of recurrence patterns and overall survival.