Biomedical subjects
Antonio Moral
Publications and source records attributed to Antonio Moral.
[Solid-pseudopapillary tumor of pancreas].
Solid-pseudopapillary tumor of pancreas is a very rare neoplasm of low malignant potential and unknown origin. It generally occurs in young women and the prognosis is usually good after complete surgical removal. Two cases of solid pseudopapillary tumor with distinct disease duration are reported.
[Intraductal papillary mucinous neoplasms of the pancreas].
INTRODUCTION: Mucin-producing pancreatic tumors account for 1% of all malignant tumors of the pancreas. Notable among these are intraductal papillary mucinous neoplasms of the pancreas, due to their variable clinical behavior, increased frequency, and the controversy surrounding the most suitable treatment and diagnostic methods. The aim of this study was to analyze the clinical presentation, epidemiological and pathological features, diagnostic methods, treatment and survival rates of these tumors. PATIENTS AND METHOD: We performed a prospective review of patients with a diagnosis of intraductal papillary mucinous neoplasm of the pancreas between 1996 and 2001. Demographic and clinical characteristics, diagnostic tests, surgical treatment, tumor characteristics and survival rates were studied. RESULTS: There were 8 patients. The mean age was 65 years. The most common clinical presentation was abdominal pain. The most frequent localization was the pancreatic head. The most common diagnostic methods used were abdominal computed tomography, endoscopic retrograde pancreatography, and serum CA 19.9 levels. Seven patients underwent pancreatic resection and only one patient was not surgically treated. The mean follow-up period was 38 months with a survival rate of 75% and a recurrence rate of 25%. CONCLUSION: Intraductal papillary mucinous neoplasms of the pancreas generally appear in the sixth decade of life. The most common presenting symptom is abdominal pain. These neoplasms typically occur in the head of the pancreas. The most commonly used diagnostic test is computed tomography and the main treatment is early surgical resection. The prognosis is good after complete resection, with a 5-year survival rate of 60-70%.
Sensory, chemical and bacteriological changes in vacuum-packed pressurised squid mantle (Todaropsis eblanae) stored at 4 degrees C.
Sensory, chemical and bacteriological changes were studied in vacuum-packed squid mantles (Todaropsis eblanae) that were pressurised at 150, 200, 300 and 400 megapascal (MPa) for 15 min at ambient temperature and stored at 4 degrees C. Sensory analysis showed that the higher the pressurisation the longer the shelf-life. Thus, the lot pressurised at 400 MPa was rejected after 28 days' storage compared with 7 days for the untreated lot. The chemical results generally corresponded with the sensory ones. Furthermore, ammonia (NH3) and trimethylamine (TMA) were produced in the pressurised lots after a pressure dependent delay. Urea decreased to low levels in all lots with the exception of the 400 MPa lot. Onset of production of agmatine, the dominant amine in this species, and other biogenic amines was delayed by increasing pressure, but still, high concentrations of these amines were detected in pressurised lots of acceptable sensory quality. Microbial counts conducted after 1 day of storage showed that the bacterial load was reduced by all pressures, reaching levels below the detection limit in the lots treated with 200-400 MPa. However, growth was resumed in all lots after a pressure dependent delay. Luminous bacteria predominated initially in the lots pressurised at 300 and 400 MPa, but were outnumbered by Enterobacteriaceae and lactic acid bacteria at the time of sensory rejection of these lots. All colonies isolated prior to pressurisation were identified as Photobacterium phosphoreum. This bacterium also resumed growth faster than other members of the endogenous microflora after pressurisation. All luminous colonies were identified as P. phosphoreum. Lactic acid bacteria isolated at the final sampling point of the lot pressurised at 400 MPa were identified as Carnobacterium piscicola and Carnobacterium divergens, while Serratia liquefaciens and Proteus vulgaris make up Enterobacteriaceae.