Biomedical subjects

Anwarul Islam

Publications and source records attributed to Anwarul Islam.

5 recordsLinked to original sources

PubMed2006

Bone marrow aspiration before bone marrow core biopsy using the same bone marrow biopsy needle: a good or bad practice?

A single-needle single-site technique for bone marrow aspiration and core biopsy has been compared with a two-needle technique, using 30 randomly selected patients who required these two investigations. In addition, two single-needle techniques were compared, aspirating immediately after penetrating the cortex or, alternatively, aspirating after the needle (without the stilette) had been advanced 20-25 mm. The two-needle technique was found to be superior to either of the single-needle techniques, which often resulted in a biopsy specimen that was denuded of bone marrow cells.

Aged↗

PubMed2006

Treatment of viral and neoplastic diseases with double-stranded RNA derivatives and other new agents.

Many attempts have been made to inhibit viral and neoplastic diseases by targeting the RNA system. The pathophysiologic significance of the microRNA system and the therapeutic potential of its manipulation are discussed. Studies of double-stranded RNA derivatives are reviewed. The therapeutic potential of one of these compounds, polyI:MPC, is emphasized. Studies of other related antiviral and antineoplastic agents are discussed, including 2'-deoxyoligocytidilates and telomerase inhibitors.

Animals↗

PubMed2005

Cytotoxic activities of ethyl acetate extract and a metabolite from a Monocillium species.

The ethyl acetate soluble fraction of a cultural broth of a Monocillium species afforded the isolation of 5-hydroxymethylfurfural. Both the extract and 5-hydroxymethylfurfural showed significant cytotoxic activities in a brine shrimp bioassay and the LC(50) values were found to be 14.96 microg/mL and 23.71 microg/mL, respectively.

Animals↗

PubMed2002

Antimicrobial activity and cytotoxicity of Aerva lanata.

Aerva lanata whole plant showed interesting antimicrobial activities (ethyl acetate and methanol extracts) and significant cytotoxic properties (petroleum ether, ethyl acetate and methanol extracts).

Amaranthaceae↗

PubMedDate not supplied

A new single-use bone marrow biopsy needle.

A new needle for taking a bone marrow biopsy sample from the posterior iliac crest is described. The needle comprises a hollow tube having a front-end portion formed to a reduced diameter. The front end is tapered by means of circumferentially spaced facets, forming a cutting edge. A series of flutes/serrations are introduced at the tapering transitional portion, between the main wider portion of the hollow tube and its reduced-diameter front-end portion. This design is new and is not available in any other conventional biopsy needle. These serrations help in its penetration through the hard cortical bone. A spacer guide, which is placed between the plastic dome of the needle and the stilette cap to enhance the ergonomics, is also new. The inside of the spacer guide is funnel shaped, through which the stilette is passed, thereby ensuring an easy and accurate alignment of the distal ends of the hollow needle and the stilette. This technique facilitates removal of the biopsy sample rearwardly out of the hollow needle particularly when the mouth (distal-end opening) of the needle is covered by extraneous bony soft tissue. In this technique, the same stilette that occupies the needle during its entry into the marrow cavity is used in sample removal. Thus, the need for an additional pusher to remove the biopsy sample from within the lumen of the needle has been eliminated.

Biopsy, Needle↗