Biomedical subjects

Apichart Singalavanija

Publications and source records attributed to Apichart Singalavanija.

3 recordsLinked to original sources

PubMed2005

Pseudophakic retinal detachment with ruptured posterior lens capsule.

The relationship between retinal detachment and posterior lens capsule rupture in pseudophakic patients was studied. Records of patients with pseudophakic retinal detachment who were admitted to Siriraj Hospital from 1992 to 2004 were reviewed. The patients were divided into 2 main groups: 1) The study group (pseudophakic retinal detachment) 79 eyes (78 cases) which was subdivided into group 1a) pseudophakic retinal detachment with intact posterior lens capsule (50 eyes), and group 1b) pseudophakic retinal detachment with ruptured posterior lens capsule (29 eyes); 2) The control group 99 eyes (90 cases) which was subdivided into group 2a) pseudophakic patients with intact posterior lens capsule (83 eyes), and group 2b) pseudophakic patients with ruptured posterior lens capsule (16 eyes). The relationship between pseudophakic retinal detachment and posterior lens capsule rupture was analyzed by Chi-square test, and risk factors were analyzed by multiple logistic regression. Retinal detachment in pseudophakic patients was found more often in males more than in females, and the average age was 57.9 +/- 11.8 years, the retinal detachment was related to posterior lens capsule rupture (p = 0.003). Patients with pseudophakic retinal detachment with a ruptured posterior lens capsule had a risk 5.7 times greater than pseudophakic patients with an intact posterior lens capsule (adjusted Odds ratio = 5.716, 95% CI = 2.118-15.427). The present study showed that posterior lens capsule rupture increased the risk of retinal detachment. Ophthalmologists should be aware of retinal detachment development after YAG capsulotomy, especially in patients who have other risk factors such as myopia, lattice degeneration, retinal break, or previous retinal detachment surgery.

Adult↗

PubMed2002

Evaluation of screening tests and prevalence of glaucoma: integrated health research program for the Thai elderly.

The purposes of this study were to evaluate the accuracy of glaucoma screening tests and to assess the prevalence of glaucoma in an elderly Thai population over 60 years of age. This was a cross-sectional study. 3706 subjects were recruited from 33 communities in the vicinity of Siriraj Hospital. All received an eye examination from ophthalmologists and general practitioners including visual acuity, Schiotz tonometry and optic disc evaluation in their residential communities. Subjects who were suspected of having glaucoma were re-examined at the Glaucoma Clinic, Siriraj Hospital. They were then classified as having definite glaucoma of a specific type or as not having glaucoma. The overall prevalence of glaucoma was 6.1 per cent (128/2092). The percentages of primary open angle glaucoma, primary angle closure glaucoma, normotension glaucoma and secondary glaucoma were 47.7 per cent, 41.4 per cent, 9.4 per cent, and 1.6 per cent respectively. The sensitivity and specificity of the screening tests performed by ophthalmologists were 100 per cent and 97.2 per cent and those performed by general practitioners were 21.7 per cent and 96.5 per cent.

Aged↗

PubMedDate not supplied

Feasibility study on computer-aided screening for diabetic retinopathy.

PURPOSE: To conduct a feasibility study of computer-aided screening for diabetic retinopathy by developing a computerized program to automatically detect retinal changes from digital retinal images. METHODS: The study was carried out in three steps. Step 1 was to collect baseline retinal image data of 600 eyes of normal subjects with normal fundi and data of 300 eyes of diabetic patients with diabetic retinopathy. All data were recorded by digital fundus camera. Step 2 was to analyse all retinal images for normal and abnormal features. By this method, the automated computerized screening program was developed. The program preprocesses colour retinal images and recognizes the main retinal components (optic disc, fovea, and blood vessels) and diabetic features such as exudates, haemorrhages, and microaneurysms. All of the accumulated information is interpreted as normal, abnormal, or unknown. Step 3 was to evaluate the sensitivity and specificity of the computerized screening program by testing the program on diabetic patients and comparing the program's results with the results of screening by retinal specialists. RESULTS: Diabetic patients (182 patients, 336 eyes) were examined by retinal specialists; 221 eyes had a normal fundus and 115 eyes had nonproliferative diabetic retinopathy. Digital retinal images were taken of these 336 eyes and interpreted by the automated screening program. The program had a sensitivity and specificity of 74.8% and 82.7%, respectively. CONCLUSIONS: The automated screening program was able to differentiate between the normal fundus and the diabetic retinopathy fundus. The program may be beneficial for use in screening for diabetic retinopathy. Further development of the program may provide higher sensitivity.

Adolescent↗