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Arne Fetveit

Publications and source records attributed to Arne Fetveit.

12 recordsLinked to original sources

Severity of illness and the use of paracetamol in febrile preschool children; a case simulation study of parents' assessments.

OBJECTIVE: Misconceptions and exaggerated fear of fever may divert parents' attention from more predictive symptoms of childhood illness, such as appetite and level of activity. This study aims at exploring how specific predefined characteristics of febrile preschool children affected parents' assessment of the severity of the condition and the perceived need for treatment with paracetamol. METHODS: Parents judged 24 constructed cases of febrile children with different levels of fever, appetite and activity, occurring at different times of the day. For each case they decided whether the child was moderately or severely ill, and whether or not they would prefer to administer paracetamol. Parents' decision-making was examined by discriminant analyses. RESULTS: Of 466 invited parents, 267 supplied information about their families and 205 accepted to participate in judging constructed cases of febrile children. A total of 159 parents responded to all cases. When evaluating the severity of the illness, 119 parents (75%) responded to one or more of the four cues describing illness. Only one of four cues was used by 80 parents (67%), and 86 (72%) parents emphasized fever. When deciding to give paracetamol, one or more of four cues was used by 102 parents (64%), while 72 parents (71%) used only one cue, and 92 parents (90%) emphasized fever. CONCLUSIONS: Parents focus on fever when they evaluate febrile illness and decide whether or not to give paracetamol. Educating parents to focus on their child's level of appetite or activity may improve management, especially when judgement is based on only one or two cues.

Acetaminophen↗

Can antibiotic prescriptions in respiratory tract infections be improved? A cluster-randomized educational intervention in general practice--the Prescription Peer Academic Detailing (Rx-PAD) Study [NCT00272155].

BACKGROUND: More than half of all antibiotic prescriptions in general practice are issued for respiratory tract infections (RTIs), despite convincing evidence that many of these infections are caused by viruses. Frequent misuse of antimicrobial agents is of great global health concern, as we face an emerging worldwide threat of bacterial antibiotic resistance. There is an increasing need to identify determinants and patterns of antibiotic prescribing, in order to identify where clinical practice can be improved. METHODS/DESIGN: Approximately 80 peer continuing medical education (CME) groups in southern Norway will be recruited to a cluster randomized trial. Participating groups will be randomized either to an intervention- or a control group. A multifaceted intervention has been tailored, where key components are educational outreach visits to the CME-groups, work-shops, audit and feedback. Prescription Peer Academic Detailers (Rx-PADs), who are trained GPs, will conduct the educational outreach visits. During these visits, evidence-based recommendations of antibiotic prescriptions for RTIs will be presented and software will be handed out for installation in participants PCs, enabling collection of prescription data. These data will subsequently be linked to corresponding data from the Norwegian Prescription Database (NorPD). Individual feedback reports will be sent all participating GPs during and one year after the intervention. Main outcomes are baseline proportion of inappropriate antibiotic prescriptions for RTIs and change in prescription patterns compared to baseline one year after the initiation of the tailored pedagogic intervention. DISCUSSION: Improvement of prescription patterns in medical practice is a challenging task. A thorough evaluation of guidelines for antibiotic treatment in RTIs may impose important benefits, whereas inappropriate prescribing entails substantial costs, as well as undesirable consequences like development of antibiotic resistance. Our hypothesis is that an educational intervention program will be effective in improving prescription patterns by reducing the total number of antibiotic prescriptions, as well as reducing the amount of broad-spectrum antibiotics, with special emphasis on macrolides.

Anti-Bacterial Agents↗

A cluster-randomized educational intervention to reduce inappropriate prescription patterns for elderly patients in general practice--The Prescription Peer Academic Detailing (Rx-PAD) study [NCT00281450].

BACKGROUND: Age-related alterations in metabolism and excretion of medications increase the risk of adverse drug events in the elderly. Inappropriate polypharmacy and prescription practice entails increased burdens of impaired quality of life and drug related morbidity and mortality. The main objective of this trial is to evaluate effects of a tailored educational intervention towards general practitioners (GPs) aimed at supporting the implementation of a safer drug prescribing practice for elderly patients > or = 70 years. METHODS/DESIGN: Approximately 80 peer continuing medical education (CME) groups (about 600 GPs) in southern Norway will be recruited to a cluster randomized trial. Participating groups will be randomized either to an intervention- or a control group. The control group will not receive any intervention towards prescription patterns in elderly, but will be the target of an educational intervention for prescription of antibiotics for respiratory tract infections. A multifaceted intervention has been tailored, where key components are educational outreach visits to the CME-groups, work-shops, audit and feedback. Prescription Peer Academic Detailers (Rx-PADs), who are trained GPs, will conduct the educational outreach visits. During these visits, a set of quality indicators (QIs), i.e. explicit recommendations for safer prescribing for elderly patients, will be presented and discussed. Software will be handed out for installation in participants' practice computers to enable extraction of pre-defined prescription data. These data will subsequently be linked to corresponding data from the Norwegian Prescription Database (NorPD). Individual feedback reports will be sent all participating GPs during and one year after the intervention. Feedback reports will include QI-scores on individual- and group levels, before and after the intervention. The main outcome of this trial is the change in proportions of inappropriate prescriptions (QIs) for elderly patients > or = 70 years following intervention, compared to baseline levels. DISCUSSION: Improvement of prescription patterns in medical practice is a challenging task. Evidence suggests that a thorough evaluation of diagnostic indications for drug treatment in the elderly and/or a reduction of potentially inappropriate drugs may impose significant clinical benefits. Our hypothesis is that an educational intervention program will be effective in improving prescribing patterns for elderly patients in GP settings.

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Sleep duration during the 24-hour day is associated with the severity of dementia in nursing home patients.

STUDY OBJECTIVES: To describe the characteristics of 24-h sleep patterns in nursing home patients with dementia, and to determine whether various degrees of dementia have any influence on total sleep duration. DESIGN AND SETTING: Cross-sectional study in a nursing home population (n = 23) consisting of patients with varying degree of dementia. Sleep was measured with actigraphy for a consecutive period of 14 days, based on individual bed and rising time, which was registered by nursing home staff. MEASUREMENTS AND RESULTS: Mean age +/- standard deviation was 86.1 +/- 7.0 (range 72-96) and mean Mini-Mental Status Examination Score (MMSE) was 13.4 +/- 5.3 (range 1-21). Ten patients had MMSE < or = 12. Sleep was extremely fragmented, with frequent wake bouts during nighttime and frequent naps during daytime. During the 24-h period, patients spent nearly 13 h asleep, distributed as more than 9 h of nighttime sleep and more than 3 h of daytime sleep. Patients with severe degree of dementia (MMSE < or = 12) slept significantly longer during the 24-h day than patients with lesser degree of dementia (MMSE > 12). There was no significant difference in age between the dementia sub-groups. CONCLUSION: Sleep duration during the 24-h day was positively correlated with the severity of dementia in nursing home patients. This is in contrast with total sleep time seen in healthy elderly, which shows a gradually decline with age. Changes in sleep patterns in dementia could be explained by co-morbid and environmental factors, as well as unknown pathological changes related to dementing illnesses.

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[Treatment of asthma--an analysis of clinical judgment among general practitioners].

BACKGROUND: The asthma patient's symptoms, use of drugs, and peak expiratory flow rates dictate treatment of asthma according to the guidelines. Our aim was to examine which information influenced the decisions of general practitioners. MATERIAL AND METHODS: Out of 100 general practitioners attending a course on asthma management, 75 responded to several constructed patient cases on asthma treatment. They decided whether or not to give oral steroids in case of an acute exacerbation and judged the quality of pharmacological treatment. Age, symptoms, body temperature, peak expiratory flow measurement and the dose of beta-2 agonists and inhaled steroids varied from patient to patient. Their attitudes to the use of oral steroids and to the usefulness of measuring peak expiratory flow were evaluated. RESULTS: Among the doctors, 52% evaluated only one characteristic of the patients when deciding upon treatment with oral steroids. The use of drugs was evaluated by one quarter of the doctors when they judged the quality of treatment. Respectively, 81% and 73% were influenced by objective measurements in these decisions. The majority of doctors applied oral steroids and measured peak expiratory flow in asthmatics. INTERPRETATION: This study indicates that general practitioners focus mainly on measured peak expiratory flow rate. The patient's symptoms ought to be given more consideration in the treatment of asthma. The patient's use of anti-asthmatics is emphasised in guidelines, but was of only limited importance to the doctors in this study.

Administration, Inhalation↗

[Sleep disturbances among nursing home patients--practical advice on treatment].

BACKGROUND: Sleep disturbances are common among nursing home patients and get worse with age and their degree of dementia. MATERIAL AND METHODS: The article is based on our own research as well as on studies and reviews in the field. RESULTS AND INTERPRETATION: Sleep disturbances among patients with dementia may have a range of internal or external causes. A thorough assessment of the patient's sleep pattern is crucial before treatment is instigated. Pharmacological interventions may have serious side effects in this population; non-pharmacological interventions have, on the other hand, shown promise.

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[Bright light treatment against sleep disturbances in nursing homes--a non-pharmacological alternative].

BACKGROUND: Age-related sleep disturbances may be caused by changes in the circadian rhythm, either by phase shifting and/or by a reduction of its amplitude. This may result in less nocturnal sleep and less wakefulness during the day. MATERIAL AND METHODS: The article is based on our own research and on relevant studies and reviews in this field. RESULTS AND INTERPRETATION: Bright light treatment may alter the phase and strengthen the existing circadian rhythm in patients with insomnia, thus creating a clearer distinction between night and day. It is reported that bright light treatment in the morning for patients with dementia may improve sleep maintenance.

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Bright-light treatment reduces actigraphic-measured daytime sleep in nursing home patients with dementia: a pilot study.

OBJECTIVE: The authors evaluated the effects of bright-light therapy on daytime sleep among nursing home patients with dementia. METHODS: Eleven patients with sleep/wake disturbances received 2 hours/day of morning bright-light exposure for 2 weeks. Sleep was measured with actigraphy and nursing staff diaries. RESULTS: Daytime sleep decreased significantly in the period from rising time to 3:00 P.M. with bright-light treatment. Treatment effects did not last into the 16-week post-treatment period. CONCLUSIONS: Bright light exposure was effective in reducing daytime sleep in nursing home patients with dementia; this finding is possibly related to bright light's acute alerting effects.

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The effects of bright-light therapy on actigraphical measured sleep last for several weeks post-treatment. A study in a nursing home population.

We investigated the time-course of nocturnal actigraphic measures, following the termination of bright-light therapy for sleep disturbances in demented nursing home patients. From an earlier study, 11 nursing home patients (86 +/- 9 years, Mini-Mental Status Examination score 12 +/- 4) with actigraphically measured sleep efficiency < 85%, were recruited to morning bright-light treatment (6000-8000 lux) 2 h per day for 14 days. Actigraphic measures were registered at pretreatment, treatment and at four monthly post-treatment periods. Each actigraphic recording period consisted of seven consecutive days. Sleep improved substantially with treatment; sleep efficiency increased from 73% to 86% and total nocturnal wake time was reduced by nearly 2 h. During the 16 weeks post-treatment period, actigraphic measures gradually returned to pretreatment levels. Sleep efficiency remained significantly higher than the pretreatment level 4 weeks after treatment termination. Sleep onset latency remained significantly reduced up until 12 weeks post-treatment. This study supports previous findings of beneficial effects of bright-light therapy for sleep disturbances in demented nursing home patients. Furthermore, these results are the first to suggest that post-treatment effects of short-term bright-light therapy may last longer than previously assumed.

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Bright light treatment improves sleep in institutionalised elderly--an open trial.

STUDY OBJECTIVES: This study evaluates the effects of bright light therapy among demented nursing home patients with sleep disturbances. DESIGN AND SETTING: 11 nursing home patients with actigraphically measured sleep efficiency below 85% took part in an open, non-randomised study where the subjects served as their own control. INTERVENTION: After two weeks of baseline measurements and two weeks of pretreatment measurements, patients received bright light exposure 2 h/day within the period 08:00-11:00 for two weeks. MEASUREMENTS AND RESULTS: Sleep-wake patterns during the 24-h day were evaluated by nursing staff ratings and wrist-worn motor activity devices (actigraphs). Sleep improved substantially with bright light exposure. Waking time within nocturnal sleep was reduced by nearly two h, and sleep efficiency improved from 73% to 86%. Corresponding improvements were found in nursing staff ratings. Effects were consistent across subjects. CONCLUSIONS: The findings add further evidence of the effectiveness of morning bright light exposure in the treatment of disturbed sleep among demented nursing home patients.

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Sleep disturbances among nursing home residents.

STUDY OBJECTIVES: This study assesses the prevalence and characteristics of sleep disturbances among an entire nursing home population, consisting of 29, mainly demented, long-term patients. DESIGN AND SETTING: Sleep was evaluated for 14 consecutive days using actigraphic measurements and nursing staff observations. No alterations were made in every-day routines or medications during the observation period. MEASUREMENTS AND RESULTS: Actigraphy showed a mean sleep onset latency of one hour and a mean wake after sleep onset of more than two hours, while there was no findings of early morning awakening. Mean sleep efficiency was 75%, and more than 13 hours were spent in bed. 72% of the subjects had sleep efficiency below 85%. Nursing staff reported sleep onset latency of more than 30 minutes in 158 of the 203 analysed days, while early morning awakening was reported in only 12 of 203 days. Actigraphical measurements and nursing staff observations gave similar results. The validity of actigraphy in this population is discussed. CONCLUSION: Sleep disturbances were common among the residents in this nursing home. Sleep onset latency was prolonged, and the patients experienced frequent wake bouts after sleep onset. The diminished ability of sustained sleep may have been influenced by the prolonged time in bed.

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