Biomedical subjects

Arnold J Boersma

Publications and source records attributed to Arnold J Boersma.

3 recordsLinked to original sources

PubMed2006

Metal-catalyzed cotrimerization of arynes and alkenes.

[Structure: see text] Cotrimerization of arynes and electron-deficient alkenes selectively affords dihydrophenanthrenes or ortho-olefinated biaryls, depending on the catalytic system employed. Our findings support a mechanism involving benzyne and a metallacycloheptadiene as key intermediates.

Journal Article↗

PubMed2006

Highly enantioselective DNA-based catalysis.

A new approach to DNA-based asymmetric catalysis is presented, which gives rise to very high enantioselectivities (up to 99% ee) in the copper catalyzed Diels-Alder reaction in water.

Catalysis↗

PubMed2005

Catalytic enantioselective conjugate addition of dialkylzinc reagents to N-substituted-2,3-dehydro-4-piperidones.

The first, highly enantioselective, copper/phosphoramidite-catalyzed conjugate addition of dialkylzinc reagents to N-substituted 2,3-dehydro-4-piperidones is described.

Journal Article↗