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Biomedical subjects

Arnold W Klein

Publications and source records attributed to Arnold W Klein.

11 recordsLinked to original sources

Techniques for soft tissue augmentation: an 'a to z'.

As society continues to seek the most opportune means to preserve youthful looks, an interest in filling substances has been reawakened. This is partly because the upper third of the face can now be successfully treated as a result of the development and recent US FDA approval of botulinum toxin (Botox). Patients seeking cosmetic improvement need no longer resort to invasive procedures that require down-time for the upper third of the face, and they are consequently seeking similar results for the lower two-thirds of the face. Filling agents have filled this void. This article discusses current techniques for soft tissue augmentation, including fat transfer and bovine collagen injections, which enable doctors to provide their patients with highly satisfactory results using minimally invasive procedures. Included in this review are an overview of the history of soft tissue augmentation and a brief prospectus of where this field of dermatology is headed in the future. Many of the currently available fillers are listed with a description of their most popular uses, possible adverse effects, manufacturers, and countries of use. Information regarding injection techniques and results from the most recent studies help to make this paper a useful source of information for experienced and novice injectors alike.

Adipose Tissue↗

Safety and efficacy of nonanimal stabilized hyaluronic acid for improvement of mouth corners.

BACKGROUND: Esthetic concern with downturned mouth corners ("mouth frown") is increasing in the aging baby-boomer generation. A new technique to offer structural support using the recently approved filler nonanimal stabilized hyaluronic acid (NASHA; Restylane, Q-med Inc., Uppsala, Sweden) is described. METHOD: Fifteen women with prominent downturned mouth corners met the inclusion criteria for the study. All were photographed before and at 1 week, 3 months, 4.5 months, and 6 months after treatment using a standardized clinical photographic system. NASHA was injected using a standardized technique with nerve block anesthesia to ensure patient comfort. RESULTS: All 15 women noted swelling, redness, and some local discomfort for several days after the injection. All noted an improvement in the downward angulation of their mouth corners at the first post-treatment visit, with at least partial improvement maintained through the 6-month post-treatment follow-up visit. CONCLUSIONS: NASHA injection to support the age-related downturn of lateral lip corners was effective, safe, and well tolerated in a small prospective study of middle-aged female subjects. Esthetic satisfaction was greatest in the first 3 months post-treatment, but 40% of subjects still noted improvement at the 6-month follow-up visit.

Adult↗

Botox for the eyes and eyebrows.

The forehead and crow's-feet (periorbital wrinkles) are among areas where Botox has been quite helpful. This cosmetic use is not approved by the Food and Drug Administration and is considered off-label. The effect, although temporary, is extremely popular with patients, has a very low incidence of side effects, and is a relatively easy technique to acquire.

Botulinum Toxins, Type A↗

Complications with the use of botulinum toxin.

This article discusses complications with the use of botulinum toxin. The following topics are explored: conditions caused by muscle spasms, resistance to botulinum toxin, cosmetic use of botulinum toxin, complications in treating hyperhidrosis, treatment of migraine headaches, and informed consent.

Botulinum Toxins, Type A↗