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Biomedical subjects

Augustus D Mazzocca

Publications and source records attributed to Augustus D Mazzocca.

22 records · Page 2Linked to original sources

Autologous chondrocyte repair of an articular defect in the humeral head.

Articular cartilage lesions remain a difficult problem for the patient and physician. A variety of procedures and treatments have been proposed to lessen symptoms and restore the articular surface. The knee joint has been the focus of the vast majority of these cartilage restoration procedures. Articular cartilage lesions of the humerus are significantly less common, and their management remains poorly defined. This paper presents a case report of a young athlete with a large full-thickness articular cartilage defect of the proximal humerus and subsequent treatment using autologous chondrocyte implantation.

Adolescent↗

Comparison of ultrasonic suture welding and traditional knot tying in a rabbit rotator cuff repair model.

The purpose of this study is to evaluate ultrasonic suture welding of monofilament suture in an animal model of rotator cuff repair with biomechanical and histologic analyses. We randomly assigned 46 shoulders in 23 rabbits to 1 of 3 treatment groups: sham-operated (n = 15), knotted (n = 15), and welded (n = 16). Supraspinatus defects were surgically created and acutely repaired with suture anchors loaded with either No. 2-0 Ethibond for knotted group or No. 2-0 nylon for welded shoulders. Eighteen weeks postoperatively, all animals were killed, and the shoulders underwent either biomechanical testing or histologic analysis. The maximum stress of the sham-operated group (20.6 N/mm2) was significantly greater than that of both the knotted (10.2 N/mm2) and welded (8.3 N/mm2) groups (P < .05), but no differences were observed between the knotted and welded groups. Although some histologic changes were noted, none was considered to be significant to distinguish either group.

Animals↗

Indirect arthroscopic rotator interval repair.

Repair of the capsular rotator interval has become a successful adjunct to arthroscopic procedures that address glenohumeral instability. This technical note presents a procedure that allows imbrication of the rotator interval in an indirect fashion regardless of pre-existing arthroscopic portals. A monofilament suture is passed percutaneously using a No.18-gauge spinal needle through the inferior portion of the rotator interval capsule. A soft tissue penetrator is passed through the anterior superior portal to retrieve the suture through the superior portion of the rotator interval capsule. A braided suture is then shuttled in the standard fashion. An arthroscopic knot pusher is placed on the inferior limb of the suture and drives this limb below the deltoid and anterior to the capsule to join the second limb for extracapsular fixation. The technique also provides for direct arthroscopic visualization of the repair and does not necessitate entry into the subacromial space. This is a reproducible procedure that allows efficient repair of the rotator interval.

Arthroscopy↗

Biomechanical comparison of patellar tendon repairs in a cadaver model: an evaluation of gap formation at the repair site with cyclic loading.

BACKGROUND: Ruptures of the patellar tendon are rare injuries. Surgical treatment for this injury is mandatory. HYPOTHESIS: Gap formation does not differ between the three patellar tendon repair techniques. STUDY DESIGN: Controlled laboratory study. METHODS: Twelve fresh-frozen cadaveric knees were used to compare three techniques of patellar tendon repairs. The standard suture repair used two Krackow sutures placed in the avulsed patellar tendon, passed through transpatellar drill holes, and secured with the knee in 30 degrees of flexion. In the second group, suture repair was augmented with a No. 5 Ethibond suture. In the third group, suture repair was augmented with a 2.0 Dall-Miles cable. Testing was performed with the specimens mounted to a custom knee jig with the tibia free, simulating the knee moment of a 70-kg person. Each knee was then cycled 250 times at 0.25 Hz. RESULTS: Gap formation across the standard suture repair averaged 7.3 mm; across the suture augmentation and cable augmentation groups it averaged 4.9 mm and 3.5 mm, respectively. CONCLUSIONS: Augmentation of patellar tendon avulsions can decrease gap formation at the repair site, allowing early mobilization. CLINICAL RELEVANCE: Gap formation seen in repair without augmentation could lead to clinical failure with resultant patella alta and extensor mechanism lag.

Aged↗