PubMed Health⌕ Search

Biomedical subjects

Aydin Ciftçi

Publications and source records attributed to Aydin Ciftçi.

5 recordsLinked to original sources

[A case of acute pancreatitis due to Weil's disease].

Leptospirosis, the most common vasculitic zoonosis in the world, is characterized with jaundice and acute renal failure. However, pancreatitis is an uncommon complication of leptospirosis. In this report, an acute pancreatitis case due to Weil's disease has been presented. A 31-year-old female patient with high levels of glucose, blood urea nitrogen, creatinine, creatine kinase, bilirubin, amylase and lipase, has been diagnosed to have leptospirosis by the high positive result (1/800) of microscopic agglutination test against Leptospira interrogans serogroup icterohemorrhagiae. The patient has been treated with supportive and symptomatic therapy, and with penicillin G for leptospirosis. Following triple hemodialysis, all the blood biochemistry tests returned to normal on the tenth day of therapy. This case was reported to draw attention to Leptospira infections which should be considered in the differential diagnosis of patients with jaundice and pancreatitis.

Acute Disease↗

[Antibody levels to diphtheria in various community segments].

The aim of this study was to detect the immune status of our population against diphtheria. For this purpose, the levels of diphtheria IgG antibodies in various age groups were investigated in 150 subjects aged over 20 years old, by using ELISA method. The positive immunity rate against diphtheria was found 62%, while there was no statistically significant difference between the rates of males (66.7%) and females (57.7%) (p > 0.05). Eighty percent of subjects aged between 20-29 years, 71.4% of 30-39 years, 50% of 40-49 years, 55.6% of 50-59 years, 47.6% of 60-69 years and 60% of 70-79 years old groups were found to have protective levels (over 0.01 IU/ml) of antibodies to diphtheria. There was no significant difference in immunity against diphtheria between these age groups (p > 0.05). However, 76% of subjects aged below 40 years old were immune to diphtheria, while 54% of subjects aged above 40 years old were so, with a statistically significant difference (p < 0.05). There was no significant difference in the rate of immunity between subjects in terms of occupation, levels of education, geographic location and vaccination status (p > 0.05).

Adult↗

[Case report: brucellosis complicated by epididymo-orchitis and paravertebral abscess].

Brucellosis which is a zoonotic infection involving many systems, is widespread in Turkey. Although muscular and skeletal system involvements are common, genitourinary system complications (epididymo-orchitis) are observed rarely. Brucellosis accompanied by abscess formation in the vertebra is generally seen in the elderly and patients with chronic diseases, while epididymo-orchitis in young patients. However, it is very unusual to detect these two complications together. In this report, a case of 42 years old male patient with epididymo-orchitis and paravertebral abscess due to brucellosis, has been presented.

Abscess↗

[Case report: a brain hydatid cyst].

Hydatid cyst is a zoonotic infection caused by larval stage of Echinococcosis granulosus. Although any organ may be involved, bone, brain and heart involvements are uncommon. The brain involvement rate varies from 1% to 3% in hydatid disease. In this report, a 42 years old female patient has been presented in whom brain hydatic cyst was diagnosed by radiological and histopathological findings.

Adult↗

The effect of ursodeoxycholic acid treatment on epidermal growth factor in patients with bile reflux gastritis.

BACKGROUND/AIMS: Study was performed to evaluate the effect of ursodeoxychlic acid treatment on epidermal growth factor, which is secreted in response to mucosal injury and is also a factor in the protection and healing of gastric mucosal injury in patients with bile reflux gastritis following cholecystectomy. METHODS: Thirty-one dyspeptic patients who had previously undergone cholecystectomy were included in the study. Upper gastrointestinal endoscopy was performed before and after a six week ursodeoxychlic acid treatment period and a biopsy was taken. Endoscopic biopsy materials were stained with epidermal growth factor (Zymed, supersensitive) immunohistochemical monoclonal kit. RESULTS: The results of endoscopic examination prior to treatment were as follows: 24 cases (77%) had reflux gastritis, five cases (16%) antral gastritis, two cases (6.5%) diffuse gastritis and all cases had enterogastric reflux. In all but one case, epidermal growth factor was found to be positive at varning degrees. After ursodeoxychlic acid treatment, complete healing was observed at endoscopy in nine cases (29%) and partial healing at varning degrees was observed in all others. The degree of positivity of epidermal growth factor reduced significantly (p<0.001). CONCLUSIONS: A decrease in the degree of epidermal growth factor positivity was observed following ursodeoxychlic acid treatment. This can be explained by the decrease in epidermal growth factor release due to healing of mucosal injury following treatment. Further investigations are needed to clarify whether ursodeoxychlic acid has a direct effect on epidermal growth factor.

Journal Article↗