Biomedical subjects

Aylin Ertan

Publications and source records attributed to Aylin Ertan.

6 recordsLinked to original sources

PubMed2007

Topography-guided vertical implantation of Intacs using a femtosecond laser for the treatment of keratoconus.

We report 2 cases of vertical implantation of Intacs (Addition Technology) for the correction of keratoconus with temporal cones. Case 1 was a 16-year-old boy. In the left eye, the refraction was -4.50 x 100, with an uncorrected visual acuity (UCVA) of 0.5 and a best corrected visual acuity (BCVA) of 0.7. The flattest meridian (K1) was 43.7@100 and the steepest meridian (K2), 46.9@10. Case 2 was a 20-year-old woman. In the left eye, the refraction was -6.00 -7.00 x 100, with a UCVA of 0.05 and a BCVA of 0.1; K1 was 51.3@25 and K2, 55.1@115. In each patient, 2 Intacs segments of 0.45 mm and 0.25 mm were inserted in the temporal and nasal regions, respectively. One year postoperatively, the UCVA was 0.7 and 0.3 in Case 1 and Case 2, respectively, and the BCVA was 0.8 and 0.5, respectively. The postoperative refraction was -2.50 x 110 in Case 1 and -5.25 x 95 in Case 2. Based on the localization of the cone, Intacs implantation appeared to improve visual acuity in keratoconic patients.

Adolescent↗

PubMed2006

Visual acuity comparison of vitrectomy with and without internal limiting membrane removal in the treatment of diabetic macular edema.

PURPOSE: To evaluate whether internal limiting membrane (ILM) peeling during vitrectomy affects vision outcome in patients with diabetic macular edema. MATERIAL AND METHOD: Fifty-eight eyes of 49 patients were included in the study. Patients with persistent diffuse clinically significant macular edema were divided into two groups according to the surgical method used. Group I subjects (15 patients; mean age 56.60+/-8.50 years; 17 eyes total) underwent vitrectomy with ILM peeling. Group II subjects (34 patients; mean age 57.52+/-11.54 years; 41 eyes total) underwent vitrectomy without ILM peeling. The data recorded for each case were type and duration of diabetes, insulin treatment (yes/no), presence of arterial hypertension, stage of diabetic retinopathy, lens status, history of macular laser treatment, and detection of posterior vitreous detachment during surgery. Visual acuity was measured preoperatively and 1 year postoperatively in decimal notation, and values were converted to logarithm of minimal-angle-of-resolution (logMAR) scores. Mean pre- and postoperative visual acuity were compared within each group, and the mean change in visual acuity in Group I was compared to that in Group II. RESULTS: There were no significant differences between the groups with respect to age; sex distribution; diabetes type; duration of diabetes; numbers of patients on insulin treatment; frequencies of hypertension, proliferative diabetic retinopathy, previous macular laser treatment; or frequency of intraoperatively confirmed posterior vitreous detachment (chi-square, P>0.05 for all). Comparison of pre- and post-operative visual acuity revealed significant improvement in both Group I (1.15+/-0.307 vs. 0.764+/-0.355 logMAR, respectively; Wilcoxon rank test, P<0.01) and Group II (1.22+/-0.516 vs. 0.829+/-0.436 logMAR, respectively; Wilcoxon rank test, P<0.001). The change in visual acuity for Group I was not significantly different from that observed in Group II (0.391+/-0.335 vs. 0.393+/-0.273 logMAR, respectively; Mann-Whitney U test, P>0.05). CONCLUSION: The visual acuity outcomes in the study indicate that vitrectomy without ILM peeling is just as effective as vitrectomy with ILM peeling in the treatment of diabetic macular edema. Both techniques led to significant and similar degrees of improvement in visual acuity.

Diabetic Retinopathy↗

PubMed2006

Vertical placement of aphakic Artisan intraocular lens in a patient with traumatic localized aniridia.

We report a 50-year-old patient who had secondary implantation of an aphakic Artisan (Ophtec) intraocular lens (IOL) that was placed vertically in the anterior chamber. The patient had had a perforating injury to the cornea that required corneal wound repair, lensectomy, and anterior vitrectomy. Because of the localized traumatic aniridia, the Artisan IOL could not be placed horizontally. Three months after surgery, the best corrected visual acuity was 0.9 and there were no complications.

Anterior Chamber↗

PubMed2006

Intrastromal ring segment insertion using a femtosecond laser to correct pellucid marginal corneal degeneration.

PURPOSE: To assess the outcomes of intrastromal ring segment (Intacs, Addition Technology) implantation using a femtosecond laser in patients with pellucid marginal corneal degeneration. SETTING: Kudret Eye Hospital, Ankara, Turkey. METHODS: In this retrospective noncomparative case series, 9 eyes of 6 patients with pellucid marginal corneal degeneration had implantation of Intacs segments by a femtosecond laser technique. Preoperative and postoperative evaluations included slitlamp examination, uncorrected (UCVA) and best corrected (BCVA) visual acuities, and keratometry by a Pentacam Scheimpflug camera (Oculus Opticgerate GmbH). All parameters were reviewed within 6 months. RESULTS: Intacs were successfully implanted in all eyes. The UCVA significantly improved from preoperatively to 6 months after Intacs implantation (mean 0.18 +/- 0.24 [SD] and 0.53 +/- 0.23, respectively). The mean difference between the preoperative and postoperative UCVA was 3.5 +/- 1.6 lines (P = .008). The BCVA also significantly improved from preoperatively to 6 months after implantation (mean 0.63 +/- 0.26 and 0.85 +/- 0.18 at 6 months, respectively). The Snellen BCVA was 1.0 in 5 eyes postoperatively. The mean difference between preoperative and postoperative BCVA was 2.3 +/- 51 lines (P = .011). The mean preoperative spherical refraction decreased from -3.86 +/- 2.91 diopters (D) to -2.77 +/- 1.43D (P = .091) and the mean cylindrical refraction, from -2.41 +/- 2.27 D to -0.94 +/- 1.07 D (P = .046). The mean central corneal curvature decreased from 48.20 +/- 4.19 D preoperatively to 46.90 +/- 5.00 D (P = .008) at 6 months and the mean posterior elevation, from 53.88 +/- 21.72 microm to 32.55 +/- 11.23 microm (P = .008). CONCLUSION: Intacs insertion using a femtosecond laser was safe and efficient in the correction of pellucid marginal corneal degeneration.

Adolescent↗

PubMed2006

Intacs insertion with the femtosecond laser for the management of keratoconus: one-year results.

PURPOSE: To assess the outcomes of intrastromal ring segment (Intacs, Addition Technology) implantation for keratoconus using the femtosecond laser. SETTING: Kudret Eye Hospital, Ankara, Turkey. METHODS: In a retrospective noncomparative case series, 118 eyes of 69 patients with keratoconus who had Intacs segments implanted with the femtosecond laser were evaluated. Preoperative and postoperative evaluations included slitlamp examination, uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), and mean keratometry values measured with the Pentacam Scheimpflug camera (Oculus Opticgerate GmbH). All parameters were assessed preoperatively and 1 year after Intacs implantation. RESULTS: Intacs were successfully implanted in all eyes. At the end of the first postoperative year, 81.3% of eyes had improved UCVA and 73.7% had improved BCVA. The mean keratometry decreased from 51.56 diopters (D) to 47.66 D, and the mean refractive spherical equivalent decreased from -7.57 D to -3.72 D. CONCLUSIONS: Intacs implantation with the femtosecond laser was safe and effective for the treatment of keratoconus. All parameters had improved by the 1-year follow-up.

Corneal Stroma↗

PubMed2003

Ocular surface changes in keratoconjunctivitis sicca with silicone punctum plug occlusion.

PURPOSE: To evaluate histopathologic and clinical response to silicone plug insertion in dry eye patients. METHODS: Punctal plugs were placed in 32 eyes of 18 dry eye patients with aqueous deficiency who were on maximum medical therapy and who had Schirmer testing with topical anesthetic measuring less than 5 mm. Pre-treatment and post-treatment (6 weeks and 1 year) evaluations included temporal and inferior quadrant impression cytology examinations, Schirmer-1, BUT, corneal fluorescein and rose-bengal staining patterns and questionnaire scores. The cytology samples were graded according to the method described by Nelson. RESULTS: There was an improvement in subjective symptoms of patients 6 weeks after punctal occlusion. Corneal fluorescein and rose-bengal staining scores decreased from a mean of 5.33 +/- 1.74 to 1.37 +/- 1.48 and from 5.90 +/- 1.2 to 2.45 +/- 1.89 (p < 0.05) respectively. BUT values increased from 2.98 +/- 1.1 to 11.3 +/- 3.1 seconds (p < 0.05) at 6 weeks post-treatment. Increase in goblet cell density was observed after punctal occlusion at 6 weeks (p < 0.05) and at 1 year (p < 0.05) compared to the pre-treatment values. After occlusion, 3% of temporal specimens had Grade 0 squamous metaplasia, 63% had Grade 1, 34% had Grade 2; while 25% of inferior specimens had Grade 0, 56% had Grade 1, 19% had Grade 2 squamous metaplasia. CONCLUSIONS: Punctum plug occlusion in keratoconjunctivitis sicca provides improvement of tear film stability, ocular surface staining scores, conjunctival squamous metaplasia grades and goblet cell density. Increased ocular surface exposure to essential tear components with punctal occlusion may be important for the genesis of these changes.

Adult↗