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Biomedical subjects

B A Blencke

Publications and source records attributed to B A Blencke.

14 recordsLinked to original sources
PubMed2000

A modular femoral implant for uncemented stem revision in THR.

We present the early results of 142 uncemented femoral stem revisions using the modular MRP-Titan system. There were 70 cases with marked preoperative femoral bone defects (Paprosky type 2C and type 3); and bone grafts were used in 31 cases. At a mean follow-up of 2.3 years five cases were re-revised due to dislocation and two due to aseptic loosening. The mean Harris hip score improved from 37.4 preoperatively to 92.4. In 122 cases progressive bone regeneration on X-ray was seen; and no further osteolysis was observed.

Adult↗
PubMed1979

Investigations with bioactivated polymethylmethacrylates.

Compound bone cement on a PMMA base with an additive of bioactive glass ceramic particles in different portions and different particle sizes are tested in animal experiments. The tissue reactions to extracorporal polymerized specimens and to in situ polymerized specimens are observed. The experiments with an implantation period up to six months demonstrate a tight bonding between the newly formed osseous tissue and the glass ceramic particles at the interface. The inflammatory reactions in the vicinity of the implant are small. It is the objective of the investigations to improve the adherance of the bone cement at the interface to achieve a more durable anchorage of bone cement in the tissue.

Animals↗
PubMed1979

[Late results of subcapital linear osteotomy in epiphysiolysis capitis femoris juvenilis (author's transl)].

107 patients with separation of the head of the femoral epiphysis were treated surgically at the Marburg Orthopaedic University Hospital during the 1955--1975 period. Followup examinations were performed in 69 patients. 34 of these had been subjected to subcapital linear osteotomy. On the average the operation had been performed 7.64 years ago. Early results were good. In most cases it was possible to correct the malposition caused by the slipping. Necroses of the femoral head were not seen more frequently than with most other methods. Necrosis of the femoral head occurred four times after 35 linear osteotomies in 34 patients. Definite roentgenological signs of arthrosis were seen about 2--3 years after the opration. These changes increased with increasing interval between operation and examination. Subcapital linear osteotomy cannot prevent the development of early arthrosis in cases where separation of the head of the femoral epiphysis exceeds 30 degrees. Despite this limitation, the patients examined during the followup study revealed a clinically favourable picture with good functioning and very considerable freedom from symptoms; it must be borne in mind in this connection that all patients were still under 35 years of age.

Adolescent↗
PubMed1978

[Study on the use of glass ceramics in osteo-odonto-keratoplasty].

Report of preparatory investigations about the usefulness of 'glass ceramics' in keratoplasty in a modification of Strampelli's method: Under the available implantation materials, glass ceramics seem to be the best as they join strongly to the bone and to interstitial tissues. As glass ceramics are suitable to keratoplasty, the necessity of loosing a tooth in osteo-odonto-keratoprosthesis after Strampelli can be avoided. Other advantages are standardization of the whole procedure, shortening of operation time and extension of indications for the operation. Based on our results, further investigations with longer implantation times, especially in eyes, are being performed at another place.

Ceramics↗
PubMed1976

Effect of pulverized implantation materials (plastic and glass ceramic) on growth and metabolism of mammalian cell cultures.

The effect of pulverized plastic and glass-ceramic materials (methylmetacrylate, MNA), which are used as implantation materials in surgical medicine, on cell growth, DNA synthesis rate (adjudged by incorporation of 3H-thymidine into DNA), glucose consumption and lactate production (glycolytic rate) was studied in asynchronous monolayer cultures of rather fast proliferating Ehrlich ascites tumor cells and rather slowly proliferating diploid human fibroblasts. Exposure of Ehrlich ascites cells to high concentrations (2 mg/ml; 10 ml medium per culture) of ceramic or plastic material resulted in a gradual inhibition of cell growth and DNA synthesis rate. Protein synthesis, as measured by the incorporation of 3H-leucine, was somewhat less affected than DNA synthesis. Also, the glycolytic rate of Ehrlich ascites cells was slightly but significantly decreased in the presence of 2 mg/ml ceramics or MMA. Exposure of Ehrlich ascites cells to 0.2 or 0.02 mg/ml over a period of 46 h revealed none or only slight inhibitory effects on growth, DNA synthesis or glycolytic rate. On the other side, growth, DNA synthesis and glycolytic rates of human fibroblasts were nearly not affected by the presence of the same concentrations (up to 2 mg/ml, incubation period: 92 h) of pulverized ceramic or plastic material (MMA). It is suggested that this differential cellular sensitivity might be related to differences in the binding (to the cell surface) or uptake of these substances and possibly to differential intracellular lysosomal activation.

Animals↗
PubMed1976

[Restitution of lunate bone necrosis in a child (author's transl)].

We reported a case of aseptic bone-cartilage necrosis of the os lunatum in a child. All indications for constitutional disposition, anatomic variations in the wrist joint or a traumatizing of the wrist joint were absent. Etiologically, a disturbance in vascularization could be assumed. The increased repair potential in children apparently led to a restitution which has not been observed in adults.

Age Factors↗
PubMed1975

[Studies on soft tissue reactions to implantation of glass ceramics (author's transl)].

This report describes the implantation of glass and glass-ceramics into soft tissues. These experiments revealed that our new glass and glass-ceramic materials are well compatible with soft tissues. The fibrous membrane surrounding such an implantat consists of normal dense collageneous connective tissue. The cells are fibroblasts and fibrocyt-like cells without any abnormal morphology. Macrophages could not be detected. However, the degree of implants solubility must be chosen with care, because high solubility of the implant increases the reaction of the surrounding soft tissues. The described materials are also compatible with osseous tissues. In our previous experiments we have already pointed out, that bonding developed between glass material and bone. Few weeks after implatation we have seen mature lamellar homegeneously mineralized bone opposed to the implant. There was no fibrous membrane between implant and bone. Longtime studies show that hitherto the described bonding exists about 2 years.

Animals↗
PubMedDate not supplied

[Possibilities for rehabilitation in spinal injuries with or without neurological deficit].

Generally spine injured persons without neurological deficits can--as long as the principles of industrial medicine are observed--be occupationally integrated without any particular rehabilitation measures within the limits of their remaining capacity. Spine injured persons, however, with remaining instabilities, serious static deficiencies and/or neurological deficits need further rehabilitation after their in-patient and immediate posthospital treatment. Spinal cord injured patients usually have to accept serious changes and limitation in all spheres of life. Rehabilitation measure in work, school and the social field are vital. Despite all efforts at rehabilitation limitations do remain among other things in work, mobility and social contacts. The preceding paper presents the tasks and results of rehabilitation of spinal cord injured persons, special consideration being given to spinal cord injured persons with supporting facts from long term studies.

Adaptation, Psychological↗
PubMedDate not supplied

[Interchangeability of the ceramic ball heads of various endoprosthesis systems. Technical report].

Today, the type of hip joint prosthesis implanted is usually chosen on the basis of the patient's age and anatomic conditions, and in particular depending on whether it is a first or second hip replacement. Not infrequently, it is desirable or necessary to combine different prosthesis systems, especially when changing prostheses. In many cases this is possible. The ceramic ball heads of different systems are also interchangeable, provided certain criteria (e.g., manufacturer) are satisfied.

Ceramics↗