Biomedical subjects

B A Casazza

Publications and source records attributed to B A Casazza.

6 recordsLinked to original sources

PubMed1999

Baseball/lacrosse injuries.

With the expansion of baseball into all age groups, the game is becoming as much a recreational sport as a youth sport. Throwing arm injuries eventually limit the participation of most players. Analysis is made of these injuries with the goal of complete rehabilitation for the baseball player. Lacrosse has also seen an increase in popularity as a recreational sport. Analysis of lacrosse injuries and rehabilitation of the most common injuries is reviewed.

Athletic Injuries↗

PubMed1980

Lymphocyte transformation induced by autologous cells. X. Soluble factors that generate cytotoxic T lymphocytes.

Cytotoxic T lymphocytes (CTL) were not generated in an autologous mixed lymphocyte reaction (MLR) in the presence of human AB serum. No CTL were generated in cultures that contained T cells and irradiated autologous, allogenetic, or hapten-modified autologous T lymphocytes. However, when allogeneic T lymphocytes or hapten-modified autologous T lymphocytes were added to an autologous MLR, specific CTL were generated. Furthermore, supernatant medium from an autologous MLR allowed the generation of specific CTL in T cell cultures to which allogeneic T cells or hapten-modified autologous T cells were added.

Cytotoxicity, Immunologic↗

PubMed1980

Immunologic studies of aging. V. Impaired proliferation of PHA responsive human lymphocytes in culture.

The impaired response to mitogens of lymphocytes from old persons has been shown to result from the presence of fewer responsive cells and the failure of these cells to divide normally after stimulation. We present additional evidence that the successive divisions of mitogen-responsive lymphocytes from old people are impaired. We labeled sister chromatids with BrdU and identified cells that were dividing for the first, second, or third time in culture. This analysis showed that lymphocyte cultures from old people contained only one-half the number of lymphocytes dividing for a second time and less than one-quarter the number of cells dividing for a third time compared with lymphocyte cultures from young people. It was shown that these changes reflected an absolute decrease in the number of second and third generation cells in cultures from old persons. No alterations in the cytokinetics of proliferation by lymphocytes from old people were found. These results provide additional evidence that mitogen-responsive lymphocytes from healthy elderly people do not undergo as many divisions in cultures with PHA as do lymphocytes from young persons.

Aging↗

PubMed1979

Lymphocyte transformation induced by autologous cells. VIII. Impaired autologous mixed lymphocyte reactivity in patients with acute infectious mononucleosis.

The autologous mixed lymphocyte reaction (MLR) is severely impaired in patients with acute infectious mononucleosis. Reactivity returned during the course of convalescence. The allogeneic MLR was not impaired in these patients. B cells from patients with infectious mononucleosis do not stimulate autologous T-cell proliferation, and this observation appears to explain the cellular basis of the impaired autologous MLR in infection. Two explanations for the B-cell defect were considered: (a) the influence of serum factors on B-cell function and (b) the effect of Epstein-Barr virus infection.

Adolescent↗

PubMedDate not supplied

The role of exercise in the prevention and management of acute low back pain.

This chapter describes the treatment guidelines for acute low back pain that were established by the Agency for Health Care Policy Research and analyzes some of the current literature on the topic. The conclusion is drawn that rehabilitation and conditioning exercises in patients with low back pain can be beneficial.

Acute Disease↗

PubMedDate not supplied

Suprascapular nerve conduction: a comparative analysis in normal subjects.

An electromyographic examination is often utilized to confirm the diagnosis of suprascapular neuropathy in patients with shoulder pain and dysfunction. The purpose of this study was to compare three compound motor action potential (CMAP) recording methods (surface electrode, monopolar needle, concentric needle) for evaluating suprascapular nerve conduction. Twenty-two normal, healthy subjects were tested with each method. Differences between the recording methods were noted for CMAP latencies and amplitudes with the monopolar needle recordings having the shortest mean latency and greatest mean amplitude. The monopolar needle recordings also appeared to give a more reproducible measurement of CMAP latency and evoked amplitude to the supraspinatus and infraspinatus. Therefore, it may be more accurate to use a monopolar needle to record suprascapular nerve conduction and determine abnormalities with a side-to-side latency difference of 0.4 ms being acceptable. Considering the diverse branching of the suprascapular nerve, and the monopolar needle's relatively small sampling area of motor fibers, it may be prudent to test conduction to multiple sites within these muscles for the most accurate assessment.

Adult↗