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Biomedical subjects

B A Edelman

Publications and source records attributed to B A Edelman.

6 recordsLinked to original sources
PubMed1992

The impact of antipsychotic drug regulations on psychotropic prescribing practices in nursing homes.

The authors prospectively studied psychotropic prescribing practices and quality assurance data in 17 nursing homes in the Baltimore area to assess the impact of federal antipsychotic drug regulations. There was a 36% reduction in prescriptions for neuroleptics over 6 months, no increase in prescriptions for sedative/hypnotics, and a small increase in prescriptions for antidepressants. The authors conclude that psychotropic drug prescribing practices and patient outcomes remain important areas of study in nursing homes.

Drug Prescriptions↗
PubMed1989

Epiglottitis in AIDS patients.

Adult epiglottitis in patients with acquired immunodeficiency syndrome has not been previously reported. A pale, floppy epiglottis with supraglottic edema, cervical lymphadenopathy, a normal to low white blood count without a shift to the left, and rapidly progressive airway obstruction characterize this entity. In this small series of patients, conservative medical management was not successful, and aggressive airway intervention with appropriate intravenous antibiotic therapy was necessary.

Acquired Immunodeficiency Syndrome↗
PubMed1984

A multiple factor study of body weight control.

A multiple factor approach toward body weight regulation was proposed which uses elements of self-perception theory to integrate seemingly unrelated or conflicting findings on the etiology of human obesity. Four factors--cue responsiveness, incidence of eating related to emotional distress, dietary restraint, and activity level--were hypothesized to influence the likelihood of obesity, with eating style being the most important variable. The existence of subgroups--normal weight and overweight individuals differing with respect to eating style, emotional-distress-related eating, dieting, and activity level--were proposed. In experimental tests on 90 Ss, predictions about the relationship of independent variables to obesity and the existence of subgroups of obese and normal weight individuals received support.

Adult↗
PubMed1981

Two chick embryonic adhesion systems: molecular vs tissue specificity.

We have investigated the adhesive properties of cells from several neural and nonneural chick embryonic tissues dissociated using modifications of the standard dissociation procedures employed routinely in this laboratory to obtain retinal cells. Each of these tissues (7-day optic tectum, retina, and heart, and 3.75-day limb bud) displayed both Ca++-dependent (CD) and Ca++-independent (CI) aggregation, the relative rates of which differed from tissue to tissue. In every case, cells prepared so as to display one mode of aggregation or the other cross-adhered readily to cells--regardless of tissue origin--displaying the same mode of aggregation. Cross adhesion was negligible between cells--even from the same tissue--prepared so as to display different modes of aggregation. Anti-retinal Fab molecules which inhibit selectively either the CI or CD aggregation of retina cells strongly inhibited the corresponding aggregation of optic tectum cells, but had no effect upon the aggregation (CI or CD) of heart cells. These results demonstrate the existence in the tissues examined of dual adhesion mechanisms similar in Ca++ dependence and recognition properties to those of the retina, but showing certain immunological distinctions from the latter. The immunological relationship among the adhesion mechanisms from the various tissues is under continuing investigation.

Animals↗