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Biomedical subjects

B A Korolev

Publications and source records attributed to B A Korolev.

At least 19 recordsLinked to original sources

Congenital pulmonary arteriovenous aneurysms.

The authors analyse their diagnostic and therapeutic experience with 26 patients suffering from congenital pulmonary arteriovenous aneurysms. Symptoms of the disease were found to depend directly on the presence and volume of arterial blood shunted into the venous bed. The volume of shunted nonoxygenated blood varied between 20 and 48 p.c.; the reflux caused hypoxic hypoxaemia with HbO2art. = 91.2 +/- 1.43%; pO2art. = 63.6 +/- 5.54 mmHg. Aimed tomography and pulmonary angiography proved most advantageous in terms of diagnostic; with their aid it was possible to identify three variants of congenital pulmonary arteriovenous aneurysm: isolated, multiple and "of the capillary haemangioma type".

Adolescent

[Complications and survival of patients after electric cardiac stimulation].

In patients with bradyarrhythmia 1105 operations were performed. Among them 528 primary stimulations were fulfilled with 2.4% lethality, 289 changes of the generator, 122 temporary electric cardiac stimulation. Complications were observed in 15.5% of the patients. Medico-technical complications took place in 5.5%, arrhythmias++--in 52.9%, purulent complications in 5.3%. Long-term results were followed-up in 405 patients within the terms from 6 months til 15 years after operation. Five years survival took place in 64.2%, ten years--in 43%, 15 years--in 27.8%. Complications in remote periods were noted in 27.6% of patients. Great attention is given to timely performed operations and dispensary observation of the patients for the improvement of results of electrocardiostimulation.

Arrhythmias, Cardiac

[Surgical correction of mitral valve stenosis and its recurrence].

The article analyses the results of surgical treatment of 1,394 patients with mitral stenosis who were operated on in the period between January 1, 1986 and April 1, 1989. Hospital mortality was 2.0%. Distinct indications for transventricular commissurotomy and mitral valve prosthetics were determined. The choice of the method for mitral stenosis correction was based on the character of the morphological changes in the cusps and subcuspal structures, which were determined during echocardiographic examination. With proper indications transventricular commissurotomy presents a small risk. Hospital mortality was 0.8% in mitral stenosis (among 1,039 patients who underwent operation 8 died) and 2.5% in recurrent stenosis (among 197 patients 5 died). Lethal outcomes were not encountered in stage 11, the mortality rate was 0.6% in stage III and 2.2% in stage IV. Mitral valve prosthetics was performed in 158 patients with 15 (9.5%) lethal outcomes. Hospital mortality was 4.5% in stage III and 10.3% in stage IV of the disease. In the group of patients with mitral stenosis hospital mortality was 7.5% (93 patients underwent operation). Hospital mortality after operations for recurrent mitral stenosis (65) was 12.3%. The initial severity of the patients' condition is still the main factor which influences unfavorably of the immediate results of mitral valve prosthetics.

Adolescent

[Ways of improving the diagnosis and prognosis in vasorenal hypertension].

Atherosclerosis, aorto-arteritis and fibromuscular dysplasia are the most common causes of vasorenal hypertension. Determination of plasma renin activity is a valuable diagnostic test at early stages of vasorenal hypertension. HLA studies demonstrated significantly elevated antigens B8 and B12 in patients with essential hypertension, and antigen A9 in patients with affected renal arteries. These findings may expand the possibilities of differential diagnosis for the selection of patients, eligible for angiographic investigation. A less than three-years duration of the disease in the presence of high plasma renin activity is a favorable prognostic criterion.

Adolescent

[Surgical correction of congenital arteriovenous aneurysms of the lungs].

The authors have analyzed results of the surgical treatment of 24 out of 26 patients observed at the clinic for arterio-venous aneurysms of the lungs. It was found that the reduction of efficiency of the gas exchange function of the lungs before operation manifested itself by arterial and venous hypoxemia with an increased arterio-venous oxygen difference and pronounced decrease of blood oxygen strain. Good results of the operative treatment, rapid recovery of blood oxygenation, disappearance of hypoxemia symptoms make the surgical method the only radical one in treatment of such patients. The operation of choice was lobectomy. No lethal outcomes followed.

Adolescent

[Results of 30 years' surgical treatment of acquired defects and diseases of the heart].

A total of 11085 patients have been operated on for rheumatic heart diseases over thirty years, 85.4% of those, for mitral stenosis or its relapse, using the "closed" method (total mortality was 2.7%). In recent years, the mortality rate has dropped to 1.5% in that group of patients. Prevention of heart failure and thromboembolic complications still are the principal problem of mitral commissurotomy. Traumatic regurgitation was seen in 2%. The operation was performed under extracorporeal circulation in 6.2% of patients. Mortality, associated with mitral prosthesis implantation, has decreased threefold (to 10.8%) over 15 years. A total of 131 patients have been operated on for constrictive pericarditis, the mortality rate was 10.7%. Primary implantation of electric pacemaker for complete transverse heart block has been performed in 196 patients, and the generator was replaced in 143 patients.

Extracorporeal Circulation

[Surgical procedure in the treatment of post-traumatic pleural empyema].

Questions of pathogenesis and tactics of treatment of 62 patients with empyema of the pleura after a closed trauma and penetrating wounds of the chest are discussed. The development of empyema was dependent on the character and degree of the injury as well as on surgical errors in diagnosis and treatment of the trauma. Coagulated hemothorax was the most frequent cause of empyema. Operation was the main method of treatment, the operation of choice being pleurectomy and decortication of the lung.

Adolescent

[Non-calculous cholecystitis as a surgical problem].

Experience with the surgical treatment of 263 patients with acalculous cholecystitis is presented. Planned and postponed operations were fulfilled on 188 patients. 75 operations were performed for urgent indications. Gangrenous cholecystitis was found in 25 of the patients, phlegmonous cholecystitis--in 46 patients, catarrhal acalculous cholecystitis in 4 patients. Three patients died from severe concomitant diseases. The authors point to the considerable incidence of destructive forms of acute cholecystitis (especially in elderly and senile patients) which requires active surgical measures after failure of a complex medicamental treatment of the attack.

Acute Disease

[Pleural empyema after closed mitral commissurotomy].

Risk factors, causes and results of the treatment of 63 patients with pleura empyema after closed commissurotomy were studied. The incidence of this complication was 0,77% per 8147 operations. Among the direct causes of empyemas there were infected blood (47,6%) and exudate (41,3%) in the pleural cavity of abscessing infarction-pneumonia (9,5%). Open drainage was found to be the most effective method of the treatment. 81% of the patients recovered. Lethality was 19%, mainly due to pyo-septic complications.

Adult

[Immediate results of choledochotomy in cholelithiasis, and its complications].

An analysis of immediate results of the operative treatment of 186 patients (choledochoduodenoanastomosis - in 86 patients, tight suture of the common bile duct - in 94 patients, external drainage of the hepatocholedocus - in 4 patients, papillosphincterotomy - in 2 patients) showed them to have no substantial difference in using choledochoduodenoanastomosis and tight suture of the common bile duct.

Adult