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Biomedical subjects

B A Porter

Publications and source records attributed to B A Porter.

34 records · Page 2Linked to original sources
PubMed1986

Magnetic resonance imaging of bone marrow disorders.

The sensitivity of MRI to marrow infiltration together with the ability to perform multiplanar imaging allows evaluation of the bone marrow in a manner that has never been feasible before. The clinical impact of this has yet to be fully realized. However, detection of focal marrow infiltration by MRI with concurrently normal conventional imaging studies has important clinical implications for staging and therapy. Proper staging of marrow-based neoplasms such as leukemia and lymphoma is fundamental to the determination of treatment and prognosis. MRI can be used to increase diagnostic certainty when a question exists concerning primary or metastatic marrow disease when other imaging studies are inconclusive. Chemical shift imaging may further improve the sensitivity and clinical utility of magnetic resonance imaging in patients with hematologic disorders involving the bone marrow.

Adult↗
PubMed1985

Hepatic perfusion abnormalities after liver transplantation.

The angiographic and CT findings in a liver transplant patient with perioperative hepatic ischemia are reported. Extensive arterial collaterals and unusual portal-to-hepatic venous shunting in the transplanted liver were observed. Post-transplant clinical, laboratory, and CT findings were compatible with partial right lobe hepatic infarction that was confirmed at autopsy. The possible relationship between the ischemic damage and intrahepatic shunting is discussed. The need for caution during preoperative angiography in potential liver transplant recipients is emphasized.

Adult↗
PubMed1985

Technetium-99m NGA functional hepatic imaging: preliminary clinical experience.

Technetium-99m galactosyl-neoglycoalbumin ( [Tc]NGA) is a radiolabeled ligand to hepatic binding protein, a receptor which resides at the plasma membrane of hepatocytes. This receptor-binding radiopharmaceutical and its kinetic model provide a noninvasive method for the assessment of liver function. Eighteen patients were studied: seven with hepatoma, eight with liver metastases, four with cirrhosis (two had concurrent hepatoma and one chronic active hepatitis), and one patient with acute fulminant non-A, non-B hepatitis. Technetium-99m NGA liver imaging provided anatomic information of diagnostic quality comparable to that obtained with other routine imaging modalities, including computed tomography, angiography, ultrasound, and [Tc]sulfur colloid scintigraphy. Kinetic modeling of dynamic [Tc]NGA data produced estimates of standardized hepatic blood flow, Q (hepatic blood flow divided by total blood volume), and hepatic binding protein concentration, [HBP]. Clinical correlation was by classical Child-Turcotte criteria (CTC). Significant rank correlation was obtained between [HBP] estimates and CTC scores (rs = -0.72, p = 0.001). This correlation supports the hypothesis that [HBP] is a measure of functional hepatocyte mass. The combination of decreased Q and markedly reduced [HBP] may have prognostic significance; all three patients with this combination died of hepatic failure within 6 wk of imaging.

Adult↗
PubMed1983

Cor triatriatum in an adult with mitral regurgitation and massive left atrial enlargement.

An unusual case of cor triatriatum in a 52-year-old woman is described in which the preoperative diagnosis was obscured by the presence of mitral valvular regurgitation and massive left atrial enlargement; such massive left atrial enlargement has not been reported before in this entity. Only the right pulmonary veins drained into the accessory chamber. The abnormal septum dividing the left atrium was demonstrated by two-dimensional but not M-mode echocardiography.

Cardiomegaly↗
PubMed1980

Three aortic arch anomalies: a review of the literature and proposal of a new classification.

Four patients with three rare aortic arch anomalies, all of which can be classified as variants of Edwards' hypothetical double aortic arch system, were studied. The diagnosis was based on angiographic findings in all cases and, in addition, on operative findings in all cases and, in addition, on operative findings in three and operative and autopsy findings in one case. All normal and anomalous variants of aortic arches may be incorporated into a new classification based upon Edwards' hypothetical double aortic arch system. In the new classification the term double aortic arch with types A, B, C, or D atresia or interruption of the left or the right arch covers all known arch anomalies. The types A, B, C, and D refer to the site of atresia or interruption of the hypothetical double aortic arch model in relationship to the ductus arteriosus and brachiocephalic vessels.

Adult↗
PubMed1978

Problem acuteness and medical record utility.

We studied the usefulness of having the patient's medical record available to the pediatrician at the time of the patient's visit. For most acute problems, the medical record had no effect on the management of the patient, whereas the record frequently affected the handling of chronic or recurrent problems. These results suggest a means of improving the effectiveness of pediatric emergency room management and also a means for defining empirically criteria for evaluation of care by record audit.

Acute Disease↗
PubMedDate not supplied

Chondrosarcoma of the temporomandibular joint: case report.

Chondrosarcoma of the head and neck region is a rarely encountered tumor. Aggressive surgical excision offers the best chance for cure. In our case, combined diagnostic techniques consisting of fine needle aspiration (FNA), computed tomography (CT), and magnetic resonance imaging (MRI) made an accurate preoperative assessment possible and greatly influenced the treatment provided.

Adult↗
PubMedDate not supplied

The beneficial effects of short pulse width acquisition and ECG-gating in digital angiocardiography.

Experimental intravenous left ventriculography and coronary angiography after aortic root injection were performed in 13 animals. Various image acquisition and digital image processing techniques were employed. These included single mask mode subtraction, integrated mask mode subtraction, ECG-gated image acquisition, TV camera read-out in interlaced mode, and pulse progressive read-out with 1- to 5-ms pulse width. High quality images were obtained consistently only after ECG-gating and use of 1- to 5-ms pulse width with pulse progressive read-out of the TV camera. Integration of four to eight background as well as contrast images all from the same phase of the cardiac cycle further improved image quality.

Angiocardiography↗
PubMedDate not supplied

MR imaging of hemorrhagic adnexal masses.

Magnetic resonance (MR) imaging, performed on 31 women with 40 surgically proven adnexal masses, was reviewed to determine whether MR can distinguish hemorrhagic from nonhemorrhagic masses. Fourteen masses proved to be hemorrhagic at surgery including functional ovarian cysts (seven cases), cystadenoma (one case), endometriomas (three cases), hematosalpinx (one case), ectopic pregnancy (one case), and parametrial extension from cervical carcinoma (one case). A high signal intensity (compared with adjacent pelvic fat) on a T1-weighted spin echo sequence was found to be a reliable indicator of hemorrhage and was demonstrated in all 14 hemorrhagic masses. The "hematocrit" effect was seen as an area of high signal intensity layering in the dependent portion of six hemorrhagic cysts. Only four of 26 nonhemorrhagic masses demonstrated high signal intensity on T1-weighted sequences and, of these, three proved to be fat-containing dermoid cysts and one was a simple cyst with adherent mesenteric fat. We conclude that high signal intensity on a T1-weighted spin echo pulse sequence is evidence for a hemorrhagic mass and that a hematocrit effect appears to be a specific sign for a hemorrhagic cyst. The clinical significance of hemorrhagic adnexal masses is discussed.

Adnexal Diseases↗
PubMedDate not supplied

Early diagnosis of spinal metastases by CT and MR studies.

Fifteen patients with known metastatic or high-risk primary cancer, normal neurologic examinations, and new abnormalities on 99mTc bone scan were evaluated with spinal CT and magnetic resonance (MR) imaging. Four patients underwent CT metrizamide myelography. Spinal CT and MR agreed in 14 of 15 patients demonstrating spinal metastases in 12 patients and benign disease in two. In one patient spinal CT was normal, but MR showed altered marrow signal consistent with metastatic disease. Epidural tumor was demonstrated by CT metrizamide myelography in four cases, all correctly identified by MR. Further evaluation of spinal MR in this setting is warranted.

Adult↗