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Biomedical subjects

B A Reid

Publications and source records attributed to B A Reid.

10 recordsLinked to original sources

Twenty-five sacrospinous ligament fixation procedures in a district general hospital: our experience.

The aim of this study was to assess the safety and medium term efficacy of sacrospinous ligament fixation procedure for grade 2 and grade 3-uterovaginal prolapse. This retrospective case study was performed between 1 July 2000 - 4 July 2003 at a District General Hospital in Scotland. For data collection, patient files, theatre records and the computer database were reviewed. The procedure was performed on 25 women. The subjective cure rate in our department was 23/25 (92%) and the recurrence rate was 2/25 (8%). These two patients underwent repeat surgery successfully. The mean follow-up time was 2 years (range 6 months to 3 years). The immediate postoperative complication rate was 2/25 (8%). The late postoperative complications rate was 7/25(28%). We concluded that the sacrospinous ligament fixation is safe and effective with good medium-term results and few postoperative complications. It should be regarded as a good primary procedure in a District General Hospital.

Aged↗

Choledochoscopy of the cystic duct as a new approach to the biliary tree.

Operative biliary endoscopy is traditionally performed through a common duct incision, through a very dilated cystic duct lumen. The development of the new ultra thin biliary scopes makes visual examination of the biliary tree possible through a normal cystic duct lumen. The operative approach to the gallbladder is unchanged. The indications for choledochoscopy of the cystic duct are the same as for operative cholangiogram. This examination can be of better quality and is less expensive than an operative roentgenogram. Unlike an operative cholangiogram, which at best visualized the bile ducts, the ultra thin scope gives the surgeon additional information concerning the ampulla of Vater, differentiating ductal spasm from stricture by its tactile feedback through the Bakes-like probe. When disease is present, it is possible for the scope to become a therapeutic instrument without the need for choledochotomy and its associated morbidity and cost. The high incidence of choledocholithiasis in this small series may be attributed to the sample size. It is also possible that more occult stones were found. If this is the case, most of these stones are being passed spontaneously and are never clinically apparent. It is those few patients who have small, occult stones that do not pass who benefit most from this new technology. This study was undertaken to develop and investigate the potential uses of a new biliary scope. These scopes require a learning period before the entire biliary tract can be visualized, but have the potential to be of significant value in the diagnosis and treatment of biliary tract disease.

Biliary Tract Diseases↗

Case-mix grouping and DRGs: making the principal diagnosis.

Labelling a hospital admission with a single disease code based on the selection of the patient's principal diagnosis poses problems for clinicians, administrators and epidemiologists. The use of a case-mix grouping classification, Diagnosis Related Groups (DRGs), allows the modification of the principal diagnosis by other factors affecting the length of stay of the patient in hospital. This system requires as its entry point a decision on which diagnosis is the principal one. The definition of principal diagnosis in Australia differs from that used in the United States where DRGs were developed. We describe a study to determine how often the use of the Australian definition leads to the allocation of a different DRG.

Abstracting and Indexing↗

Pulmonary microvascular clearance of radiotracers in human cardiac and noncardiac pulmonary edema.

We examined the integrity of the alveolocapillary membrane in human cardiac (hydrostatic) (group 1) and noncardiac (permeability) (group 2) edema by measuring the clearance of two intravenously administered radiotracers from the blood to suctioned bronchoalveolar secretions (BAS), representing pulmonary edema fluid, and compared the clearances to simultaneously measured pulmonary capillary wedge pressure (PCWP) and colloid osmotic pressure (COP), representing the intravascular Starling forces, Pmv and pimv. 111In-labeled diethylenetriamine pentaacetic acid (DTPA), mol wt 504, a hydrophilic radiotracer that equilibrates with extracellular water, and 125I-labeled human serum albumin (HSA), mol we 69,000, were injected intravenously. Samples of blood and BAS were then collected hourly for 405 h, and clearances were calculated. We found the clearance of both radiotracers to be greater in group 2 than in group 1 patients, despite a low mean PCWP-COP gradient, indicating greater alveolocapillary membrane permeability membrane in noncardiac, than in cardiac edema. Furthermore, 111In-DTPA clearance was linearly correlated with the PCWP-COP gradient in both groups (group 1, R2 = 0.726, P less than 0.001; group 2, R2 = 0.879, p less than 0.001 as was the clearance of 125I-HSA in group 2 (R2 = 0.35, P less than 0.027). Clinically, the data suggest that in cardiac and noncardiac pulmonary edema the transmicrovascular flux of small and large solutes may be favorably influenced by therapeutic alterations aimed at widening the intravascular PCWP-COP gradient. However, the greater permeability of the alveolocapillary membrane in noncardiac edema would prohibit any major resolution of edema by simple therapeutic alterations of this gradient.

Capillary Permeability↗