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Biomedical subjects

B A Rodan

Publications and source records attributed to B A Rodan.

At least 37 records · Page 2Linked to original sources

Fibrous mass complicating epidural morphine infusion.

The benefits of continuous epidural morphine infusion using an implanted pump delivery system to control intractable cancer pain have recently been described. Most articles on this subject relate to dosage, technique, degree of pain relief, and tolerance. There are some anticipated complications of the treatment related to the surgical implantation of the system and drug toxicity. We present a complication presumably related to the epidural catheter. A fibrous reaction that developed around the catheter tip progressed into a mass. This caused a significant displacement of the spinal cord with the development of long tract symptoms. Identification of this abnormality using myelography and computed tomography led to prompt surgical decompression resulting in improvement of the patient's condition.

Aged↗

Incidental sonographic detection of renal cell carcinoma.

Renal cell carcinoma is not an uncommon finding in our population. Since the symptoms of renal cell carcinoma may mimic those of other abdominal disease, we strongly advocate ultrasonic evaluation of the entire abdomen when screening patients with pain. Whether our three patients' symptoms were due to gallbladder disease or the incidentally detected renal cell carcinoma is relatively inconsequential, as long as detection of the potentially life-threatening lesion is achieved.

Adenocarcinoma↗

Subclavian steal: treatment with percutaneous transluminal angioplasty.

Three cases of subclavian steal were treated with percutaneous transluminal angioplasty of the subclavian stenosis. One patient had dilatation of the lesion three separate times, without CNS complications. Initial screening with continuous wave Doppler ultrasound proved successful in identifying patients with the subclavian steal phenomenon and any associated carotid disease.

Angioplasty, Balloon↗

Tracheobronchial mucoid pseudotumors.

A collection of mucus, indistinguishable from tumor, can be shown in the tracheobronchial tree, particularly during tomography. These "mucoid pseudotumors" may be distinguished from true tumors by documenting their disappearance after having the patient cough.

Aged↗

Solitary pulmonary metastases in high-risk melanoma patients: a prospective comparison of conventional and computed tomography.

A prospective comparison of chest radiography, conventional tomography, and computed tomography (CT) in the detection or confirmation of solitary pulmonary nodules was made in 42 patients with high propensity for pulmonary metastases due to advanced local (Clark level IV or V) or regional malignant melanoma. Unequivocal nodules were revealed by chest radiography in 11 patients, conventional tomography in 16, and computed tomography in 20 patients. Both plain films and tomography in three of these 20 were normal, but follow-up verified pulmonary metastases. Computed tomography detected more pulmonary nodules than conventional tomography in 11 patients in addition to identifying lesions in extrapulmonary sites. Therefore, chest CT is recommended before institution of immunotherapy or surgical removal of a solitary pulmonary melanoma metastasis. Once chemotherapy had been instituted for bulky regional or cutaneous involvement, however, the findings of either conventional or computed tomography were comparable in this study.

Adult↗

Mediastinal pancreatic pseudocyst.

We have described a case of extension into the mediastinum by a pancreatic pseudocyst. This rare phenomenon should be included in the differential diagnosis of mediastinal mass lesions. We advocate the use of CT in evaluating a mediastinal mass to determine its solid or cystic nature, size, extent, and relationship to adjacent structures.

Adult↗

Calcification in pulmonary metastases.

A large variety of neoplasms can produce calcified lung metastases. Three unusual examples are presented and the relevant literature is reviewed. Each case involves a neoplasm not previously reported to produce calcified lung metastases: malignant mesenchymoma, fibrosarcoma of the breast, and medullary carcinoma of the thyroid. The sarcomas are reported in the literature to develop calcified lung metastases are osteogenic sarcoma, chondrosarcoma, synovial sarcoma, and giant cell tumour. Among carcinomas, the papillary and mucinous adenocarcinomas are the histological types most likely to develop calcified lung metastases. The metastases of a number of other tumours have calcified after antineoplastic therapy. Calcification in metastases arises through a variety of mechanisms: bone formation in tumour osteoid, calcification and ossification of tumour cartilage, dystrophic calcification and ossification of tumour cartilage, dystrophic calcification and mucoid calcification. Since calcified lung metastases can strongly resemble granulomas or hamartomas, a reasonable suspicion of malignancy is necessary when evaluating calcified pulmonary nodules.

Adult↗

Postpericardiotomy syndrome.

Postpericardiotomy syndrome is an immune phenomenon that occurs from several days to months after surgical incision of the pericardium. Prominent clinical features include fever, pericarditis, and pleuritis. Of 161 patients with Wolff-Parkinson-White syndrome who underwent surgical treatment, 50 (31%) developed postpericardiotomy syndrome 4-12 days later. Of these 50 patients, 38 had sufficiently complete records for analysis. Significant radiographic abnormalities were present in 30 (79%) of these 38 patients, pericardial effusions in 19 (50%), pleural effusions in 26 (68%), and pulmonary infiltrates in four (10%). These radiographic signs almost always developed within 2 days of the onset of symptoms, either before or after, and were essentially absent in the 76 patients who did not clinically develop the syndrome. Postoperative radiographs can be extremely valuable in first suggesting or confirming the suspicion of postpericardiotomy syndrome.

Adolescent↗

Massive calcification of the mitral annulus in a 17-year-old patient with juvenile rheumatoid arthritis and systemic lupus erythematosis.

Mitral annulus calcification (MAC), while a relatively frequent autopsy finding in older patients, is rare in childhood. Such calcification has generally been regarded as a degenerative change and of no clinical significance. Recent studies have shown that MAC may be associated with hemodynamically significant lesions including mitral insufficiency, arrhythmias, heart block, and, rarely, mitral stenosis. We have studied a case of massive calcification in the mitral annulus in a 17-year-old girl with juvenile rheumatoid arthritis and systemic lupus erythematosis. In this case, the MAC was considered secondary to the rheumatoid disease. MAC in younger patients with no history of rheumatic fever or bacterial endocarditis suggests an associated connective tissue disorder.

Adolescent↗

Splenic abscess due to Salmonella typhimurium bacteremia.

We have described a case of splenic abscess due to Salmonella typhimurium bacteremia. We believe abdominal roentgenograms and computed tomography are most effective in the preoperative evaluation of splenic abscess. Salmonella infections should be considered in the differential diagnosis of splenic abscess.

Abscess↗