Trends in cocaine use in the general population.
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Biomedical subjects
Publications and source records attributed to B A Rouse.
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This manuscript presents a comprehensive assessment of the current illegal drug use problem among Hispanics by analyzing the recent findings on this subject. Information is provided on the prevalence of illegal drug use by drug type, age, and specific Hispanic group, and on the accessibility and availability of drug treatment facilities to Hispanics. The consequences of illegal drug use upon the well-being of Hispanics are discussed. Recommendations on additional research are made.
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The prevalence and patterns of smokeless tobacco use and its correlates were assessed in the National Institute on Drug Abuse National Household Survey of residents 12 years of age and older. Overall, 11% of the general population have "ever tried" chewing tobacco, snuff, or other smokeless tobacco. Of these, 5% were former users and 3% used smokeless tobacco almost daily in the past year. Rates of its use differed significantly by sex, age group, race, region, and metropolitan area size. Although females were far less likely to try it, those who did were as likely as males to be daily users. Smokeless tobacco users were also more likely to use alcohol, cigarettes, and marijuana. In general, those who used smokeless tobacco almost daily were more likely to report poor health and hospitalization for illness or injury in the past year, even when other substance use was controlled. Smokeless tobacco users also were more likely to report symptoms of depression. Finally, some substituted smokeless tobacco for cigarettes, but youths (12-17 yr old) were more likely than older tobacco users to use both forms of tobacco regularly.
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A variety of data sources and research studies are used to examine changes in the prevalence of cocaine use and assess the population at risk. The issues of progression to more intensified use of cocaine and the use of other drugs in combination with cocaine are investigated. Consequences of cocaine use are discussed, as is the potential impact of changing routes of administration on both the frequency and severity of those consequences.
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Disulfiram had more pronounced sedative effects on healthy normal subjects with low levels of plasma dopamine-beta-hydroxylase (DBH) than it did on subjects with higher levels. It is suggested that DBH levels might provide a means of predicting increased susceptibility to disulfiram side effects.
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